Saturday February 16, 2019

Sex Hormone Levels Linked to Heart Disease in Post-Menopausal Women

Postmenopausal women with high testosterone at heart disease risk

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Sex Hormone Levels Linked to Heart Disease in Post-Menopausal Women
Sex Hormone Levels Linked to Heart Disease in Post-Menopausal Women. Pixabay

Postmenopausal women with a higher blood level of the testosterone male hormone and a higher ratio of the oestrogen hormone could be at a higher risk of developing heart disease later in life, finds a study.

Among post-menopausal women, a higher ratio of testosterone/oestradiol — a major oestrogen produced in the ovaries — was associated with an elevated risk for incident cardiovascular disease (CVD), coronary heart disease and heart failure events, while higher levels of testosterone were associated with increased CVD and coronary heart disease.

On the other hand, higher oestradiol levels were associated with a lower coronary heart disease risk.

“Although sex hormone levels may be linked to future cardiovascular events, it is unclear what the best intervention is to modify sex hormone levels for risk reduction,” said Erin D. Michos, Associate Professor at the Johns Hopkins University in Maryland, US.

Representational image.
Representational image. Pixabay

“However, a sex hormone profile higher in male hormones may identify a woman at higher risk for cardiovascular disease who may benefit from other risk reduction strategies,” Michos added.

The risk for cardiovascular disease is much lower in women than men until women reach the age of 50 years of age, then risk rises dramatically after menopause.

Previous studies have demonstrated that higher androgen and lower oestrogen levels are associated with risk factors for heart disease in post-menopausal women; however, other studies show conflicting results, so the relationship between sex hormones and cardiovascular events in post-menopausal women remains unclear.

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The new research, published in the Journal of the American College of Cardiology, evaluated the association of sex hormone levels with incident cardiovascular disease, over a 12-year follow-up in 2,834 post-menopausal women free of cardiovascular disease at baseline.

Sex hormone concentrations were measured using fasting serum samples. Sex hormone levels after menopause were associated with women’s increased risk of CVD in later life. (IANS)

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Diet Drinks Increase Stroke Chances in Postmenopausal Women

The results in post-menopausal women may not be generalisable to men or younger women. 

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The results in post-menopausal women may not be generalisable to men or younger women. Pixabay

Are diet drinks your choice? Beware, your heart could be at risk. A new study suggests that drinking diet drinks was associated with an increased risk of having a stroke among post-menopausal women, researchers say.

The stroke is was caused by a blocked artery, especially small arteries.

The study, published in the journal Stroke, showed that compared with women who consumed diet drinks less than once a week or not at all, women who consumed two or more artificially sweetened beverages per day were 23 per cent more likely to have a stroke, 31 per cent more likely to have ischemic stroke, and 29 per cent were at risk of developing heart disease (fatal or non-fatal heart attack).

In addition, there was a 16 per cent risk of deaths from any cause.

 

 

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A new study suggests that drinking diet drinks was associated with an increased risk of having a stroke among post-menopausal women, researchers say. Pixabay

Furthermore, stroke risks more than doubled in women without previous heart disease or diabetes and obese women without previous heart disease or diabetes, findings revealed.

“Many well-meaning people, especially those who are overweight or obese, drink low-calorie sweetened drinks to cut calories in their diet. Our research and other observational studies have shown that artificially-sweetened beverages may not be harmless and high consumption is associated with a higher risk of stroke and heart disease,” said lead author Yasmin Mossavar-Rahmani, Associate Professor at the Albert Einstein College of Medicine in the US.

For the study, researchers included 81,714 post-menopausal women aged 50-79 years.

The results in post-menopausal women may not be generalisable to men or younger women.

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Furthermore, stroke risks more than doubled in women without previous heart disease or diabetes and obese women without previous heart disease or diabetes. Pixabay

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“The American Heart Association suggests water as the best choice for a no-calorie beverage,” suggested Rachel K. Johnson, Professor at the University of Vermont in the US.

“Since long-term clinical trial data are not available on the effects of low-calorie sweetened drinks and cardiovascular health, given their lack of nutritional value, it may be prudent to limit their prolonged use,” Johnson added. (IANS)