Saturday February 24, 2018

3-D miniature Female Reproductive System may Boost Safety and Effectiveness in testing New Drugs

The device has a series of cables and pumps that cause media (simulated blood) to flow between wells and will open doors into the causes of endometriosis, fibroids and some cancers

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New York, March 29, 2017: Scientists have, in a breakthrough, developed a 3-D based miniature female reproductive tract that will boost safety and effectiveness in testing new drugs for diseases such as fibroids, endometriosis, cancer and infertility in women’s reproductive organs.

The new 3-D device — called EVATAR — is made with human tissue, can fit in the palm of your hand, and could help use stem cells of an individual patient and create a personalised model of their reproductive system.

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“This is nothing short of a revolutionary technology. It’s the ultimate personalised medicine, a model of your body for testing drugs,” said lead investigator Teresa Woodruff, a reproductive scientist and Director at Northwestern University in the US.

“This will help us develop individualised treatments and see how females may metabolise drugs differently from males,” Woodruff added.

The organ models are able to communicate with each other via secreted substances, including hormones, to closely resemble how they all work together in the body, mimicking what is actually happening in the body, the researchers said in the paper published in the journal Nature Communications.

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The device has a series of cables and pumps that cause media (simulated blood) to flow between wells and will open doors into the causes of endometriosis, fibroids and some cancers.

The system also will allow scientists to test millions of compounds in the environment and new pharmaceuticals to understand how they affect the reproductive system and many other organs in the body.

“This technology will help us look at drug testing and drug discovery in a brand new way,” Woodruff said. (IANS)

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National Investigation Agency Arrests one in Kerala Terror Camp Case

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Kerala Terror camp
The person arrested was identified as Azharudeen aka Azhar, 24, a resident of Narath in Kerala. ians

New Delhi, Oct 10: The National Investigation Agency (NIA) on Tuesday said it has arrested one accused of organising Kerala Terror Camp Case in Kannur district in 2013.

The person arrested was identified as Azharudeen aka Azhar, 24, a resident of Narath in Kerala.

An NIA official told IANS that Azhar was arrested on Monday night. He would be produced before the trial court in Ernakulam later on Tuesday.

The counter-terror agency said the arrest involved April 23, 2013, case when the secret training camp was organised by Thanal Foundation Trust inside one of its building to impart training in using of swords and explosives.

On January 20, 2016, the National Investigation Agency Special court had found 21 persons of the Popular Front of India (PFI) guilty of the charges including criminal conspiracy, membership of unlawful assembly, possession of arms and explosive substances, inciting communal disharmony, assertions prejudicial to national integration besides organising the terrorist camp.

The case was first registered by the state police, before it was taken over by the NIA in August 2013.(IANS)

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