Wednesday March 20, 2019

Nearly 40 Individual HPV Types Linked to HIV Infection

Regarding prevention and treatment, Brown recommends the HPV vaccine, widely provided to everyone regardless of sex, gender, or sexual orientation before sexual debut, and for genital wart treatment

0
//
HIV
Nearly 40 individual HPV types linked to HIV infection. Pixabay

Scientists have for the first time identified 37 individual types of the human papillomavirus, or HPV, that are specifically linked to human immunodeficiency virus (HIV) infection.

The findings showed that a person with any HPV type, more than one HPV type, or high-risk HPV are more likely to test positive for HIV.

“Although most studies have shown a general link between HPV and HIV co-infection, our findings illustrate the strong relationship between individual HPV types and HIV infection,” said lead author Brandon Brown, Associate Professor at the University of California, Riverside.

“Some HPV types are more linked to cancer and others to warts. This further illustrates the potential utility of HPV vaccine for men who have sex with men and trans women, not only for HPV prevention but also possibly for HIV prevention,” Brown added.

Brown explained that previous research has shown that HPV, in general, was linked to HIV infection, but his research team looked at infection with 37 HPV types and found that individual types are linked, “which is more specific than saying HPV is linked”.

The study, published in the journal PLOS ONE, identified HPV types such as HPV16, 18, 31, 33, 35, 52, 58, linked to HIV.

HIV Aids
Computer simulations can also predict the spread of HIV: Study. Flickr

For the study, the team investigated nearly 600 men who have sex with men, or MSM, and transgender women in Lima, Peru.

Brown and his colleagues started with two groups, one with genital warts and one without, and followed participants over two years to see who contracted HIV.

Of the 571 participants who completed at least two study visits, 73 acquired HIV in two years — a 6 per cent HIV incidence rate.

Previous study with female sex workers showed that the HPV vaccine still provided protection to high-risk groups.

Also Read- Anupam Kher Wants History Not to Misjudge Manmohan Singh

Regarding prevention and treatment, Brown recommends the HPV vaccine, widely provided to everyone regardless of sex, gender, or sexual orientation before sexual debut, and for genital wart treatment.

“Even if the vaccine is not provided before sexual debut, there can be strong benefit if given at any time to prevent HPV-associated disease and also HIV,” he said.

“We know that HPV is the most common STI, and we know that HPV vaccine works to prevent chronic HPV infection. What we need now is to implement the vaccine in a better way. The availability in many other developing countries is low at best and absent at worst.” (Bollywood Country)

Next Story

Good News! HIV Now Has A Cure Possible

The London man is HIV-free after receiving a stem cell transplant from a donor with a rare genetic mutation that made him resistant to HIV. His cancer has also gone into remission.

0
doctors
Scientists have been searching for a cure for HIV/AIDS for close to 40 years. The director of UNAIDS called news that a man in London has been functionally cured of HIV a "breakthrough." VOA

An HIV-positive man in Britain has become the second known adult worldwide to be cleared of the AIDS virus. At a conference in Seattle, the U.N. agency leading the global effort to end AIDS said the agency is greatly encouraged by the possibility of an HIV-positive man being cured, but there is still a long way to go.

Scientists have been searching for a cure for HIV/AIDS for close to 40 years. The director of UNAIDS called news that a man in London has been functionally cured of HIV a “breakthrough.” Stephane Dujarric, a spokesman for the U.N. secretary-general, made the announcement.

“The breakthrough gives us great hope for the future, but also shows how far we are from the point of ending AIDS with science, as well as the absolute importance to continue to focus on HIV prevention and treatment efforts,” he said.

The London man is HIV-free after receiving a stem cell transplant from a donor with a rare genetic mutation that made him resistant to HIV. His cancer has also gone into remission.

Professor Ravindra Gupta at University College London said the man is now off anti-AIDS medication.

“We waited 16 months before stopping in the post-transplant period just to make sure that the cancer was in remission, the patient was well and that the measures we had of the HIV reservoir in the body showed that there was very, very little virus there, if any at all,” he said.

HIV
“We now have reason to believe that the Berlin patient was not a one-off case… meaning it is possible to nearly, or even completely, eliminate HIV from an infected person,” he said. Pixabay

Gupta hesitates to call it a cure, but this is the second patient to show no signs of the HIV virus after a similar stem cell transplant. The first man was an American treated in Berlin 12 years ago. Dr. Rowena Johnston, director of research at amfAR, the Foundation for AIDS Research, says this second success is significant.

“We now have reason to believe that the Berlin patient was not a one-off case… meaning it is possible to nearly, or even completely, eliminate HIV from an infected person,” he said.

Also Read: World’s Largest Airlines Yet To Work on Their “Emissions Intensity” Goals

Just like the Berlin patient, Gupta says the British man who is being called the “London patient,” also received stem cells from a donor with a rare mutated gene called CCR5.

“If you transplant those cells into someone who already has HIV, you may protect those new cells from infection,” he said. (VOA)