Tuesday June 18, 2019

Nearly 40 Individual HPV Types Linked to HIV Infection

Regarding prevention and treatment, Brown recommends the HPV vaccine, widely provided to everyone regardless of sex, gender, or sexual orientation before sexual debut, and for genital wart treatment

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HIV
Nearly 40 individual HPV types linked to HIV infection. Pixabay

Scientists have for the first time identified 37 individual types of the human papillomavirus, or HPV, that are specifically linked to human immunodeficiency virus (HIV) infection.

The findings showed that a person with any HPV type, more than one HPV type, or high-risk HPV are more likely to test positive for HIV.

“Although most studies have shown a general link between HPV and HIV co-infection, our findings illustrate the strong relationship between individual HPV types and HIV infection,” said lead author Brandon Brown, Associate Professor at the University of California, Riverside.

“Some HPV types are more linked to cancer and others to warts. This further illustrates the potential utility of HPV vaccine for men who have sex with men and trans women, not only for HPV prevention but also possibly for HIV prevention,” Brown added.

Brown explained that previous research has shown that HPV, in general, was linked to HIV infection, but his research team looked at infection with 37 HPV types and found that individual types are linked, “which is more specific than saying HPV is linked”.

The study, published in the journal PLOS ONE, identified HPV types such as HPV16, 18, 31, 33, 35, 52, 58, linked to HIV.

HIV Aids
Computer simulations can also predict the spread of HIV: Study. Flickr

For the study, the team investigated nearly 600 men who have sex with men, or MSM, and transgender women in Lima, Peru.

Brown and his colleagues started with two groups, one with genital warts and one without, and followed participants over two years to see who contracted HIV.

Of the 571 participants who completed at least two study visits, 73 acquired HIV in two years — a 6 per cent HIV incidence rate.

Previous study with female sex workers showed that the HPV vaccine still provided protection to high-risk groups.

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Regarding prevention and treatment, Brown recommends the HPV vaccine, widely provided to everyone regardless of sex, gender, or sexual orientation before sexual debut, and for genital wart treatment.

“Even if the vaccine is not provided before sexual debut, there can be strong benefit if given at any time to prevent HPV-associated disease and also HIV,” he said.

“We know that HPV is the most common STI, and we know that HPV vaccine works to prevent chronic HPV infection. What we need now is to implement the vaccine in a better way. The availability in many other developing countries is low at best and absent at worst.” (Bollywood Country)

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HIV Patients at Higher Risk of Developing Heart Diseases

The researchers emphasised on the importance of a healthy lifestyle that includes smoking cessation, adequate physical activity, eliminating or reducing the amount of alcohol consumed and a healthy diet

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AIDS, Indonesia, HIV
Students with their faces painted with messages pose during an HIV/AIDS awareness campaign to mark the International AIDS Candlelight Memorial, in Chandigarh, India, May 20, 2018. (VOA)

HIV patients are at a significantly higher risk of suffering from heart and blood vessel diseases as compared to those without the infection, according to a new scientific statement.

In the statement, published in the Circulation journal, the researchers indicated that the heart disease risk among HIV patients occurs due to interactions between traditional risk factors, such as diet, lifestyle and tobacco use; and HIV-specific risk factors, such as a chronically activated immune system and inflammation characteristic of chronic HIV.

“Considerable gaps exist in our knowledge about HIV-associated diseases of the heart and blood vessels, in part because HIV’s transition from a fatal disease to a chronic condition is relatively recent, so long-term data on heart disease risks are limited,” said Matthew J. Feinstein, lead author and Assistant Professor at Northwestern University in Chicago.

The statement, released by American Heart Association, highlighted that tobacco use, which increases the risk of cardiovascular diseases, is common among people living with HIV.

Forty-two per cent of HIV patients were smokers, it said.

HIV. Pakistan
Participants hold placards in the shape of the red ribbon, the universal symbol of awareness and support for those living with HIV, as a hot air balloon is released during an awareness campaign ahead of World AIDS Day in Kolkata, India. VOA

The researchers said that another risk factor is the aging population of HIV patients as 75 per cent of HIV patients are over 45 years of age.

“Aging with HIV differs greatly from the aging issues facing the general population,” said Jules Levin, Founder and Executive Director of the National AIDS Treatment Advocacy Project.

“On average, people living with HIV who are over 60 years old have 3-7 medical conditions, including heart attacks, strokes, heart failure, kidney disease, frailty and bone diseases and many take 12-15 medications daily,” Levin added.

The researchers insisted that more research is needed for informed decision-making and effective CVD prevention and treatment in the aging population of people living with HIV.

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“There is a dearth of large-scale clinical trial data on how to prevent and treat cardiovascular diseases in people living with HIV,” said Feinstein.

The researchers emphasised on the importance of a healthy lifestyle that includes smoking cessation, adequate physical activity, eliminating or reducing the amount of alcohol consumed and a healthy diet. (IANS)