Wednesday January 29, 2020

Check out the 9 Genes Responsible For Eyebrow Colours

Therefore, an in-depth understanding of the pigmentation genes will help improve the treatment of these diseases

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Get Those Expressive Eyes With Perfect Eyebrows
Get Those Expressive Eyes With Perfect Eyebrows. Pixabay

An international research team has for the first time identified nine genes responsible for eyebrow colours.

Eyebrow colour is one of the most recognisable visual traits of the human body. It has a strong correlation with hair colour, but scientists believe in the existence of overlapping and unique genetic components for both traits.

Previous studies on human eyes, hair, and skin colour have identified multiple gene variants, but no findings for eyebrow colour have been reported as of yet.

For the new study, researchers from China, the Netherlands, Australia, Britain and the US analysed samples of 6,513 European individuals, and graded colours into four categories: red, blond, brown and black, Xinhua reported.

They found that eight genes, previously known pigmentation genes, could affect both eyebrow and hair colour, such as gene variant MC1R, responsible for both blond eyebrows and red hair.

In addition, C10orf11 is the newly-identified gene that only affects eyebrow colours.

Beware of too-thin brows as it can actually make you look older.
Beware of too-thin brows as it can actually make you look older. Pixabay

With these findings, researchers developed an eyebrow colour prediction model and are ready to improve it by studying the different age distributions.

Such a DNA-based eyebrow colour prediction model would improve the human phenotype research and be useful in future forensic applications, said lead author Liu Fan, researcher at the Beijing Institute of Genomics of the Chinese Academy of Sciences.

“Based on the new discoveries, we can more accurately infer individual hair, eyes, skin, eyebrow colour and other phenotypic information just from a DNA sample,” Fan said in the paper published in the Journal of Investigative Dermatology.

Also Read- Nose of Kids Hold Clues to Serious Lung Infections

Eyebrow colour is controlled by genes that affect production of pigment. Melanin, for example, is a protective pigment that can block the ultraviolet radiation. Melanin-related gene abnormalities can lead to many diseases, such as albinism, and increase the risk of skin cancer.

Therefore, an in-depth understanding of the pigmentation genes will help improve the treatment of these diseases, the researchers noted. (IANS)

Next Story

Researchers Identify 102 Genes Associated with Autism

It's critically important that families of children with and without autism participate in genetic studies because genetic discoveries are the primary means to understanding the molecular, cellular, and systems-level underpinnings of autism

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Autism
Researchers have discovered how a Genetic Alteration that increases the risk of developing Autism and Tourette's impairs brain communication. Pixabay

In the largest genetic sequencing study of autism spectrum disorder (ASD) to date, researchers have identified 102 genes associated with risk for autism.

The discovery shows significant progress towards teasing apart the genes associated with autism from those associated with intellectual disability and developmental delay, conditions which often overlap.

According to the World Health Organisation (WHO), one in 160 children has an autism spectrum disorder (ASD).

ASDs begin in childhood and tend to persist into adolescence and adulthood. In most cases the conditions are apparent during the first five years of life.

“This is a landmark study, both for its size and for the large international collaborative effort it required.

“With these identified genes we can begin to understand what brain changes underlie ASD and begin to consider novel treatment approaches,” said Joseph D Buxbaum, Director of the Seaver Autism Center for Research and Treatment at Icahn School of Medicine at Mount Sinai.

For the study published in the journal Cell, an international team of researchers from more than 50 sites collected and analyzed more than 35,000 participant samples, including nearly 12,000 with ASD, the largest autism sequencing cohort to date.

Autism
Families of children with autism face high physical, mental and emotional burdens, are sometimes ridiculed and even accused of child abuse, says a new study. Pixabay

Using an enhanced analytic framework to integrate both rare, inherited genetic mutations and those occurring spontaneously when the egg or sperm are formed, researchers identified the 102 genes associated with ASD risk.

Of those genes, 49 were also associated with other developmental delays.

The larger sample size of this study enabled the research team to increase the number of genes associated with ASD from 65 in 2015 to 102 today.

In addition to identifying subsets of the 102 ASD-associated genes, the researchers showed that ASD genes impact brain development or function and that both types of disruptions can result in autism.

“Through our genetic analyses, we discovered that it’s not just one major class of cells implicated in autism, but rather that many disruptions in brain development and in neuronal function can lead to autism,” said Buxbaum.

Also Read: Vaping May not Help with Smoking Cessation: Report

It’s critically important that families of children with and without autism participate in genetic studies because genetic discoveries are the primary means to understanding the molecular, cellular, and systems-level underpinnings of autism.

“We now have specific, powerful tools that help us understand those underpinnings, and new drugs will be developed based on our newfound understanding of the molecular bases of autism,” the researchers noted. (IANS)