Saturday December 14, 2019

Check out the 9 Genes Responsible For Eyebrow Colours

Therefore, an in-depth understanding of the pigmentation genes will help improve the treatment of these diseases

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Get Those Expressive Eyes With Perfect Eyebrows
Get Those Expressive Eyes With Perfect Eyebrows. Pixabay

An international research team has for the first time identified nine genes responsible for eyebrow colours.

Eyebrow colour is one of the most recognisable visual traits of the human body. It has a strong correlation with hair colour, but scientists believe in the existence of overlapping and unique genetic components for both traits.

Previous studies on human eyes, hair, and skin colour have identified multiple gene variants, but no findings for eyebrow colour have been reported as of yet.

For the new study, researchers from China, the Netherlands, Australia, Britain and the US analysed samples of 6,513 European individuals, and graded colours into four categories: red, blond, brown and black, Xinhua reported.

They found that eight genes, previously known pigmentation genes, could affect both eyebrow and hair colour, such as gene variant MC1R, responsible for both blond eyebrows and red hair.

In addition, C10orf11 is the newly-identified gene that only affects eyebrow colours.

Beware of too-thin brows as it can actually make you look older.
Beware of too-thin brows as it can actually make you look older. Pixabay

With these findings, researchers developed an eyebrow colour prediction model and are ready to improve it by studying the different age distributions.

Such a DNA-based eyebrow colour prediction model would improve the human phenotype research and be useful in future forensic applications, said lead author Liu Fan, researcher at the Beijing Institute of Genomics of the Chinese Academy of Sciences.

“Based on the new discoveries, we can more accurately infer individual hair, eyes, skin, eyebrow colour and other phenotypic information just from a DNA sample,” Fan said in the paper published in the Journal of Investigative Dermatology.

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Eyebrow colour is controlled by genes that affect production of pigment. Melanin, for example, is a protective pigment that can block the ultraviolet radiation. Melanin-related gene abnormalities can lead to many diseases, such as albinism, and increase the risk of skin cancer.

Therefore, an in-depth understanding of the pigmentation genes will help improve the treatment of these diseases, the researchers noted. (IANS)

Next Story

Genetic Alteration Can Increase Risk of Developing Autism and Tourette’s Syndrome

Some researchers also found that the ability of the Thalamic brain regions to communicate with other brain areas was impaired by the genetic deletion

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Genetic
Genetic deletion disrupts a brain area known as the Thalamus, compromising its ability to communicate with other brain areas. Pixabay

Researchers have discovered how a Genetic Alteration that increases the risk of developing Autism and Tourette’s impairs brain communication.

People with a genetic deletion known as chromosome 2p16.3 deletion often experience developmental delay and have learning difficulties.

They are also around 15 times more likely to develop Autism and 20 times more likely to develop Tourette’s Syndrome, but the mechanisms involved are not completely understood.

Using brain imaging studies, neuroscientists showed that deletion of the gene impacted by 2p16.3 deletion (Neurexin1) have impacts on the function of brain regions involved in both conditions.

This genetic deletion disrupts a brain area known as the Thalamus, compromising its ability to communicate with other brain areas, said the study published in the journal Cerebral Cortex.

“We currently have a very poor understanding of how the 2p16.3 deletion dramatically increases the risk of developing these disorders,” said lead researcher Neil Dawson of Lancaster University in Britain.

“However, we know that the 2p16.3 deletion involves deletion of the Neurexin1 gene, a gene that makes a protein responsible for allowing neurons to communicate effectively,” Dawson said.

Deletion of the Neurexin1 gene affects brain areas involved in Autism and Tourette’s including the Thalamus, a collection of brain regions that play a key role in helping other brain areas communicate with each other.

Autism
Researchers have discovered how a Genetic Alteration that increases the risk of developing Autism and Tourette’s impairs brain communication. Pixabay

Changes were also found in brain regions involved in processing sensory information and in learning and memory.

Importantly, the researchers also found that the ability of the Thalamic brain regions to communicate with other brain areas was impaired by the genetic deletion.

ALSO READ: Physical illness And injury Raises The Risk of Suicide in Men, Not Women: Study

They then tested the ability of a low dose of the drug Ketamine, which is used clinically at higher doses as an anesthetic, to normalise the alterations in brain function induced by genetic deletion.

“Intriguingly our data suggest that Ketamine can restore some aspects of the brain dysfunction that results from 2p16.3 deletion and suggests that ketamine, or other related drugs, may be useful in treating some of the symptoms seen in autism and Tourette’s,” Dawson said. (IANS)