Wednesday October 24, 2018

Study: 9/11 Survivors May Face the Risk of Developing Increased Heart, Lung Diseases Years Later

The monumental terrorist attacks on the World Trade Centre on September 11 have managed to leave behind scars that are much more than just skin-deep

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The 9/11 attacks. wikimedia
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  • A recent study shows that the survivors may be at an increased long-term risk of asthma, other similar respiratory diseases, and heart attack
  • The findings indicate that intense exposure on a single day – the first day of the disaster – contributes substantially to the risk of developing chronic conditions
  • The authors used data from the WTC Health Registry cohort to examine the long term health effects of acute exposure to the dust cloud or physical injury caused by the terrorist attack

Washington, July 18, 2017: The terrorist attacks on the World Trade Centre on September 11, 2001, have made the accident a historical event, having left behind scars that are much more than just skin-deep. A recent study shows that the survivors may be at an increased long-term risk of asthma, other similar respiratory diseases, and heart attack.

The association between physical injury or acute exposure to the dust cloud on the morning of September 11, 2001, and chronic diseases up to ten to eleven years later (2010-2012) were examined and analyzed by researchers at the New York City Department of Health and Mental Hygiene.

According to the corresponding author Robert Brackbill, the findings indicate that intense exposure on a single day – the first day of the disaster – contributes substantially to the risk of developing chronic conditions. He also mentioned, “Continued monitoring of people who were present in the vicinity of the World Trade Centre on 11th September by medical providers is warranted for the foreseeable future.”

The researchers observed that the number of types of injuries, such as fractures, head injuries, or sprains, a person sustained on 11th September 2001 was associated with an increased risk of angina or heart attack in a dose-dependent manner. This means that the risk of having angina or a heart attack went up with every additional injury type.

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According to ANI, exposure to dust, PTSD and being a rescue worker, as well as current smoking were associated with a higher risk of non-neoplastic lung disease (lung conditions not involving tumors) other than just asthma. Dust exposure, on its own, was associated with an increased risk of asthma. But none of these risk factors were associated with a higher risk of diabetes.

Out of the total number of 8,701 people who were a part of this study, 41% had been intensely exposed to the dust cloud, 10% had a single injury, 2% had two types of injury and 1% had three or more.

In the survey, the researchers also noticed 92 incident cases of heart disease, 327 new cases of diabetes, 308 cases of asthma, and 297 cases of non-neoplastic lung disease among 7,503 area workers, 249 rescue workers, 131 residents and 818 bystanders – the most heavily exposed groups.

The authors used data from the WTC Health Registry cohort to examine the long term health effects of acute exposure to the dust cloud, or physical injury caused by the terrorist attack. The WTC Health Registry is responsible for monitoring the physical and mental health of 71,431 persons exposed to the 9/11 attacks.

In the study, a lack of specific information on the severity, location, and treatment of injuries, as well as on the circumstances in which they were sustained meant that the number of types of injuries was used as a proxy measure of injury severity. However, the authors mentioned that it has been shown by previous researchers that more than one type of injury can be associated with increased risk of death and longer stays in the hospital.

The study has been published in the Injury Epidemiology journal.

– prepared by Durba Mandal of NewsGram. Twitter @dubumerang

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Anaemia Drug Can Aid in Recovery After Heart Attack

However, further studies will be needed to confirm if the same benefits are seen in humans, they noted

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Heart Disease
Concern has often focused on the toxicity or carcinogenic properties of the metals, particularly at high doses. Pixabay

Drugs currently undergoing development to treat anaemia — lack of blood — could be repurposed to help prevent people with Type-2 diabetes from developing heart failure, according to a new research.

Researchers found that after a heart attack, a protein called HIF acts to help heart cells survive.

In people with diabetes, fats accumulate within the heart muscle and stop the HIF protein from becoming active. This means that a person is more likely to suffer lasting heart muscle damage, and develop heart failure after a heart attack.

“After a heart attack, people with Type-2 diabetes are more likely to develop heart failure more quickly, but we have not fully understood the reasons why that is the case,” said lead researcher Lisa Heather, research student at the University of Oxford in the UK.

“What we have shown with this research is that the metabolism of people with Type-2 diabetes means they have higher levels of fatty acids in the heart. This prevents signals going to the heart protective protein telling it to ‘kick-in’ after a heart attack,” she added.

Representational image.
Representational image. (IANS)

In the study, published in the Journal of the American College of Cardiology, the team treated diabetic rats with a drug known to activate the HIF protein, and were able to encourage the heart to recover after a heart attack.

However, these initial results suggest that several drugs known to activate HIF and currently undergoing phase-III clinical trials to treat people with anaemia, could potentially be given to people with diabetes, immediately after a heart attack in the future, the researchers said.

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“This research in rats has not only identified the mechanism that could explain why people with Type-2 diabetes have poorer outcomes after a heart attack, but also a practical way this might be prevented,” the researchers explained.

However, further studies will be needed to confirm if the same benefits are seen in humans, they noted. (IANS)