Sunday April 21, 2019

American Scientists Design Adhesive Gel to Repair Eye Injury Without Surgery

The researchers expected to start clinical trials to test the technology in human patients in approximately one year

0
//
migraine, dry eyes
The study showed that people with migraine had a 20 per cent higher risk of having dry eye disease, the HealthDay reported. Pixabay

American scientists have designed an adhesive gel that can seal wound or ulcers on the surface of the eye, thus sparing the need for eye surgery.

The study published on Wednesday in the journal “Science Advances” showed that the gel packed with light-activated chemicals can not only close the defect but also regenerate it, Xinhua news agency reported.

“We wanted this material to allow the cells of the cornea to mesh with the adhesive and to regenerate over time to mimic something as close to the native cornea as possible,” said the paper’s co-corresponding author Reza Dana, a professor of ophthalmology at Harvard Medical School.

The gel is clear and viscous in a dropper or syringe, but when exposed to blue light in a short time, it hardens to take on features of a native cornea, and the the cornea cells gradually grow into and become one with the gel, according to the study.

The gel is the first to use visible blue light as opposed to ultraviolet light, which carries a level of toxicity.

Cataracts
Representational image. Pixabay

In a preclinical study, the researchers administered the gel at 20 per cent concentration to corneal defects of 3 mm, and applied visible light for four minutes, leading to a firm adhesion to the defect.

One day later, they observed a transparent, smooth eye surface without inflammation. Over time, the tissue regenerated and the new tissue showed few differences with the native one, according to the study.

Also Read- Tesla in-car Browser to be Upgraded to Chromium

The researchers expected to start clinical trials to test the technology in human patients in approximately one year.

Corneal injuries are a common cause of visual impairment worldwide, with more than 1.5 million new cases of corneal blindness reported every year. Some of them require corneal transplants that carry risks of post-transplant complications like infection or rejection. (IANS)

Next Story

Vatican Children’s Hospital Carries Out A Pioneering Surgery On a 30-month-old

Surgeons performing a laparoscopy have an extremely detailed picture of the patient's anatomy, allowing more precise incisions with a lower risk of bleeding.

0
surgery
Toddler receives mother's kidney, part of liver in pioneering transplant. Pixabay

Surgeons at the Vatican children’s hospital in Rome have carried out a pioneering surgery in which a Lebanese woman’s kidney and part of her liver were transplanted in her 30-month-old son, who suffers from a rare metabolic disorder.

Doctors at the Bambin Gesu hospital performed path-breaking laparoscopic surgery on the left side of the woman’s liver and on her kidney.

The boy, named Danil, suffers from primary hyperoxaluria, a severe form of a rare metabolic disease called oxalosis, characterised by the formation of calcium oxalate deposits in organs and tissues.

Oxalosis can cause urinary infections and permanent kidney damage, and in the most severe cases, can stunt the patient’s growth and cause brittle bones that are vulnerable to fractures. It affects one in 100,000-333,000 people.

Surgery
All such patients treated at the Bambin Gesu have had dialysis during surgery and several days afterwards, and all the operations have been successful. Flickr

“This operation could be the first of its kind in the world,” the Bambin Gesu said in a statement.

“We are not aware of previous cases in which laparoscopic surgery has been carried out to transplant the same donor’s liver and kidney one after the other.”

The team at the Bambin Gesu that carried out the laparoscopic transplant in Danil of part his mother’s liver was led by Marco Spada, while the transplant of her kidney to the toddler was spearheaded by Luca dello Strologo.

Laparoscopic surgery to transplant a kidney from a living donor to a recipient is well-established, while the use of the minimally invasive technique for liver transplants is a more recent operation that is only done in the most specialist centres and, in Italy, currently only at the Bambin Gesu.

Surgery
Bambin Gesu hospital , Vatican. Flickr

All such patients treated at the Bambin Gesu have had dialysis during surgery and several days afterwards, and all the operations have been successful, according to the hospital. In the past 24 months, it has performed 32 liver or kidney transplants from living donors and 98 from deceased donors.

Also Read: Exposure to Arsenic, Lead may Spike up Risk of Heart Disease

The advantages of laparoscopy include a significant reduction in surgical trauma which reduces the length of time patients need to spend in hospital, less need for painkilling drugs, a lower risk of postoperative complications and a more rapid return to normal life, according to the experts.

And thanks to high-resolution (3K and 4K) and three-dimensional imaging technology, surgeons performing a laparoscopy have an extremely detailed picture of the patient’s anatomy, allowing more precise incisions with a lower risk of bleeding. (IANS)