Never miss a story

Get subscribed to our newsletter


×
Cancer Ribbon. Pixabay

Artificial Intelligence can help detect one of the most common forms of blood cancer – acute myeloid leukaemia (AML) – with high reliability, new research has found.

Their approach, based on the analysis of the gene activity of cells found in the blood, could support conventional diagnostics and possibly accelerate the beginning of therapy, said the study published in the journal iScience.


In the early stages the symptoms of AML can resemble those of a bad cold. However, AML is a life-threatening disease that should be treated as quickly as possible.

“With a blood test, as it seems possible on the basis of our study, it is conceivable that the family doctor would already clarify a suspicion of AML,” said Joachim Schultze, a research group leader at the German Center for Neurodegenerative Diseases (DZNE).

“And when the suspicion is confirmed, the patient is referred to a specialist. Possibly, the diagnosis would then happen earlier than it does now and therapy could start earlier,” added Schultze, who is also Head of the Department for Genomics and Immunoregulation at the LIMES Institute of the University of Bonn in Germany.

For the study, the researchers focused on the “transcriptome”, which is a kind of fingerprint of gene activity.

In each and every cell, depending on its condition, only certain genes are actually “switched on”, which is reflected in their profiles of gene activity.

Exactly such data – derived from cells in blood samples and spanning many thousands of genes – were analysed in the current study.


“Artificial intelligence is now one of the fastest-growing areas in all of science and one of the most talked-about topics in society.” VOA

“The transcriptome holds important information about the condition of cells. However, classical diagnostics is based on different data. We therefore wanted to find out what an analysis of the transcriptome can achieve using artificial intelligence, that is to say trainable algorithms,” said Schultze.

Data from more than 12,000 blood samples – these came from 105 different studies – were taken into account for the study.

Approximately 4,100 of these blood samples derived from individuals diagnosed with AML, the remaining ones had been taken from individuals with other diseases or from healthy individuals.

The scientists fed their algorithms parts of this data set. The input included information about whether a sample came from an AML patient or not.

Also Read: Apple Brings its Super Lucrative Bug Bounty Programme for Researchers

“The algorithms then searched the transcriptome for disease-specific patterns. This is a largely automated process. It’s called machine learning,” said Schultze.

Based on this pattern recognition, further data was analysed and classified by the algorithms – categorised into samples with AML and without AML.

Put into application, this method could support conventional diagnostics and help save costs, said Schultze. (IANS)


Popular

IANS

The Perroayuda Welfare Foundation (PWF), recently held a Mega Stray Feeding Drive in Lajpat Nagar with the goal of feeding all of the area's stray animals.

By IANSlife

Many stray animals are trying to survive as the temperature in the capital continues to drop. Many strays lose this battle trying to find food and warmth under a scrap of clothing or caged up in the corner of streets. The Perroayuda Welfare Foundation (PWF), a Delhi-based animal welfare organisation, recently held a Mega Stray Feeding Drive in Lajpat Nagar with the goal of feeding all of the area's stray animals. These wonderful Samaritans come from all around Delhi-NCR with one goal in mind: to rescue, feed, and adopt all animals in need.

woman holding a dog Many stray animals are trying to survive as the temperature in the capital continues to drop. | Af.Mil

Keep Reading Show less
Bisma Mahendra / Unsplash

Flag of Indonesia

Indonesian lawmakers passed a law on the relocation of the nation's capital to the island of Kalimantan, which shares borders with Malaysia and Brunei, from the most populated island of Java. The move is a step forward in one of the most ambitious projects initiated by the country's President Joko Widodo, Xinhua news agency reported. Some former presidents had floated ideas of relocating the capital city in the past. The president, widely known as Jokowi, three years ago vowed to relocate the capital city to the province of East Kalimantan due to a number of issues like high population density and land subsidence in Jakarta which is home to more than 10 million people.


Keep Reading Show less
Photo by Hannah Lim on Unsplash

Pets, especially dogs and cats, can reduce stress, anxiety, and depression

By Olivia Sarkar

Everyone has a special affinity with their pets. Furry friends are there for you in good times and bad, and they know how to cheer you up. After a hard day's work there's nothing like coming home to your own bundle of joy. Here's a round up of some celebrities who can't do without their pets:

Shraddha Kapoor
Shraddha Kapoor's pet, Shyloh, is her best buddy. Kapoor is frequently spotted spending peaceful time with her all-time bestie.

Shraddha Kapoor Shraddha is frequently spotted spending peaceful time with her all-time bestie. | IANS

Keep reading... Show less