Saturday December 7, 2019

This AI Tool Can Predict Mortality Of Heart Failure Patients

Researchers develop a tool that can predict mortality of heart failure patients

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This artificial intelligence (AI) tool can predict life expectancy in heart failure patients. Pixabay

Researchers have developed an artificial intelligence (AI) tool to predict life expectancy in heart failure patients.

The machine learning algorithm based on de-identified electronic health, records data of 5,822 hospitalised or ambulatory patients with heart failure at UC San Diego Health in the US.

“We wanted to develop a tool that predicted life expectancy in heart failure patients, there are apps where algorithms are finding out all kinds of things, like products you want to purchase,” said Avi Yagil, Professor at University of California.

“We needed a similar tool to make medical decisions. Predicting mortality is important in patients with heart failure. Current strategies for predicting risk, however, are only modestly successful and can be subjective,” Yagil added.

From this model, a risk score was derived that determined low and high risk of death by identifying eight readily available variables collected for the majority of patients with heart failure:Diastolic blood pressure, Creatinine, Blood urea nitrogen, White blood cell count, Platelets, Albumin and Red blood cell distribution.

Yagil said the newly developed model was able to accurately predict life expectancy 88 per cent of the time and performed substantially better than other popular published models.

“This tool gives us insight, for example, on the probability that a given patient will die from heart failure in the next three months or a year,” said researcher Eric Adler.

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The mortality of a heart failure patient can be predicted. Pixabay

“This is incredibly valuable. It allows us to make informed decisions based on a proven methodology and not have to look into a crystal ball,” he added.

The tool was additionally tested using de-identified patient data from the University of California San Francisco and a data base derived from 11 European medical centers.

“It was successful in those cohorts as well,” said Yagil.

“Being able to repurpose our findings in independent populations is of utmost importance, thus validating our methodology and its results,” Yagil added.

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Researchers said the partnership between physicists and cardiologists was critical to developing a reliable tool and extensive knowledge and experiences from both sides proved synergetic.

The study was published in the European Journal of Heart Failure. (IANS)

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Generalised Anxiety Disorder During Teenage Can Lead to Harmful Drinking Habits

Using questionnaire and clinical interview data from more than 2,000 participants, researchers found generalised anxiety disorder at age 18 was linked to frequent drinking

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Research has shown that links between mental health problems, such as Anxiety disorders, and alcohol are common and complex. Pixabay

Researchers at the University of Bristol have found evidence of an association between generalised Anxiety disorder at age 18 and harmful drinking three years later.

The study, published in the journal Drug and Alcohol Dependence strengthens the evidence for a relationship between anxiety and later alcohol use as the researchers accounted for other factors such as adolescent smoking and cannabis use, and parental anxiety and alcohol use.

“Helping adolescents to develop positive strategies for coping with anxiety, instead of drinking alcohol, may reduce the risk of future harmful drinking. However, we cannot determine if the relationship is causal, because we used an observational study design,” said Maddy Dyer.

Using questionnaire and clinical interview data from more than 2,000 participants, researchers found generalised anxiety disorder at age 18 was linked to frequent drinking, frequent bingeing, hazardous drinking, and harmful drinking at age 18.

Generalised anxiety disorder continued to be associated with harmful drinking at age 21.

Drinking to cope was also strongly associated with more harmful drinking, but it did not appear to influence associations between anxiety and alcohol use.

Harmful drinking was measured using a special test developed by the World Health Association.

On average, adolescents with anxiety drank at more harmful levels regardless of whether they tended to drink alcohol for coping reasons or not.

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Researchers at the University of Bristol have found evidence of an association between generalised Anxiety disorder at age 18 and harmful drinking three years later. Pixabay

“Our own research has shown that links between mental health problems, such as anxiety disorders, and alcohol are common and complex,” said Mark Leyshon, Senior Policy and Research Manager at Alcohol Change UK.

For example, anxiety can be both a result of stopping drinking and a risk factor in beginning to drink too much, as this new study suggests.

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“We need more research to help us better understand the connections between alcohol and mental health, as well as high-quality, accessible, integrated support for substance misuse and mental health issues,” Leyshon added. (IANS)