Saturday December 15, 2018

Air Pollution Linked to Changes in Heart Structure

Higher exposures to the pollutants were linked to more significant changes in the structure of the heart, the findings showed

0
//
Air Pollution.
Air pollution may also lead to changes in heart structure. Pixabay
Republish
Reprint

Researchers have found that people exposed to even low levels of air pollution can have changes in the structure of the heart, similar to those seen in the early stages of heart failure.

For every one extra microgram per cubic metre of PM2.5 — small particles of air pollution — and for every 10 extra microgram per cubic metre of nitrogen dioxide (NO2), the heart enlarges by approximately 1 per cent, showed the findings of the Britain-based study published in the journal Circulation.

“Although our study was observational and hasn’t yet shown a causal link, we saw significant changes in the heart, even at relatively low levels of air pollution exposure,” said one of the researchers Nay Aung from Queen Mary University of London.

For the study, the researchers looked at data from around 4,000 participants in the UK Biobank study, where volunteers provided a range of personal information, including their lifestyles, health record and details on where they have lived.

Higher exposures to the pollutants were linked to more significant changes in the structure of the heart,
Higher exposures to the pollutants were linked to more significant changes in the structure of the heart. Pixabay

Participants also had blood tests and health scans, and heart MRI (magnetic resonance imaging) was used to measure the size, weight and function of the participants’ hearts at fixed times.

The team found a clear association between those who lived near loud, busy roads, and were exposed to nitrogen dioxide or PM2.5 and the development of larger right and left ventricles in the heart.

Also Read: Air Pollution Linked to 3.2 Million New Diabetes Cases in One Year

The ventricles are important pumping chambers in the heart and, although these participants were healthy and had no symptoms, similar heart remodelling is seen in the early stages of heart failure.

Higher exposures to the pollutants were linked to more significant changes in the structure of the heart, the findings showed. (IANS)

Click here for reuse options!
Copyright 2018 NewsGram

Next Story

Exposure To Air Pollution Linked To Breast cancer: Study

Government can plan for new designs for industrial and commercial facilities to cut down on the occupational exposures.

0
Air pollution, asia
Air pollution shortens life by more than one year in India. Wikimedia Commons

Women working near busy roads are at high risk of developing breast cancer, due to traffic-related air pollution, researchers have warned.

The team, from University of Stirling in Scotland, analysed the case of a woman who developed breast cancer after spending 20 years working as a border guard at the busiest commercial border crossing in North America.

The woman was one of, at least, five other border guards who developed breast cancer within 30 months of each other and, at another nearby crossing, a cluster of seven other cases was noted.

Pollution, pollutants, India, air pollution, WHO, diwali
India’s Rashtrapati Bhawan, or the Presidential Palace is partly visible due to smog as traffic plies on Rajapth, the ceremonial boulevard in New Delhi. VOA

According to Michael Gilbertson, the findings “infer a causal relationship” between breast cancer and very high exposures to traffic-related air pollution containing mammary carcinogens. A link between nightshift work and cancer was also identified.

“This new research indicates the role of traffic-related air pollution in contributing to the increasing incidence of breast cancer in the general population,” Gilbertson said.

The group of women all developed a cancer believed to have been caused by exhaust fumes in what researchers have branded a ‘new occupational disease’.

There is a one in 10,000 chance the cases were a coincidence, the study published in the journal New Solutions said, because the cancers were all so similar and close together.

air pollution, breast cancer
Breast cancer cell, Wikimedia Commons

A review of previous research confirmed that BRCA1 and BRCA2 genes — which try to stop tumours growing — can be “silenced” by exposures to dioxins and polycyclic aromatic hydrocarbons – both found in exhaust fumes.

BRCA2 gets rapidly degraded in the presence of aldehydes – also components of exhaust fumes.

Also Read: Chemotherapy May Not Be Needed To Treat Breast Cancer: Study

“There is much more research to be undertaken,” Gilbertson said. “But we now have plausible mechanisms for inferring how the BRCA1/2 tumour suppressors in this highly-exposed border guard became dysfunctional and likely contributed to the ongoing epidemic of sporadic, early onset, premenopausal breast cancer among her colleagues.

“With this new knowledge, industry and government can plan for new designs for industrial and commercial facilities to cut down on the occupational exposures to traffic-related air pollution,” Gilbertson said. (IANS)