Monday July 23, 2018

Air pollution can Increase Risk of Dementia in Elder Women: Study

These women were also 92 per cent more likely to develop dementia, including Alzheimer's.

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New York, Feb 1, 2017: Elderly women exposed to tiny air pollution particles may face an increased risk of dementia, including Alzheimer’s disease, a study has found.

The findings showed the fine particulate matter (PM 2.5) — coming from power and automobile plants — could invade the brain and wreak havoc in older women who live in these places.

The air quality of those places which exceeds the US Environmental Protection Agency’s standard of 81 percent were more likely to experience global cognitive decline.

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These women were also 92 per cent more likely to develop dementia, including Alzheimer’s.

“Microscopic particles generated by fossil fuels get into our body directly through the nose into the brain,” said Caleb Finch, Professor at the University of Southern California (USC).

“Cells in the brain treat these particles as invaders and react with inflammatory responses, which over the course of time, appear to exacerbate and promote Alzheimer’s disease,” Finch added.

The effects were stronger in women who had the APOE4 gene — a genetic variation that increases the risk for Alzheimer’s.

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For the general population, the risk was nearly 21 per cent, the researchers said.

The study also “provides the evidence of a critical Alzheimer’s risk gene possibly interacting with air particles to accelerate brain ageing,” said Jiu-Chiuan Chen, Associate Professor at the USC.

For the study, published in the Nature journal Translational Psychiatry, the team analysed data of 3,647 of 65- to 79-year-old women who did not have dementia.

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In another experiment, the scientists chronically exposed female mice carrying the APOE4 gene to nano-sized air pollution for 15 weeks.

The results showed that the exposure of mice to air particles damaged neurons in the hippocampus — the memory centre vulnerable to both brain ageing and Alzheimer’s disease.

-IANS

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Air Pollution Linked to 3.2 Million New Diabetes Cases in One Year

Nearly 10 million years of healthy life were lost in 2016 due to pollution-linked diabetes, representing about 14 per cent of all years of healthy life lost due to diabetes from any cause

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Air Pollution Linked to 3.2 Million New Diabetes Cases in One Year
Air Pollution Linked to 3.2 Million New Diabetes Cases in One Year. Pixabay

Outdoor air pollution even at levels deemed safe may be associated with an increased risk of diabetes globally, with India being at a greater risk due to lack of air cleaning policies, scientists said in a report in Lancet.

The findings showed that air pollution contributes to development of diabetes by reducing insulin production and triggering inflammation, which prevents the body from converting blood glucose into energy that the body needs.

The overall risk of pollution-related diabetes is tilted more toward lower-income countries such as India that lack the resources for environmental mitigation systems and clean-air policies, Lancet Planetary Health report said.

“Our research shows a significant link between air pollution and diabetes globally,” said Ziyad Al-Aly, from the University of Washington in St. Louis, US.

“We found an increased risk, even at low levels of air pollution currently considered safe by the US Environmental Protection Agency (EPA) and the World Health Organization (WHO).

“This is important because many industry lobbying groups argue that current levels are too stringent and should be relaxed. Evidence shows that current levels are still not sufficiently safe and need to be tightened,” Aly explained.

Representational image.
Representational image. Pixabay

The researchers estimated that pollution contributed to a little more than three million new diabetes cases globally in 2016, which represented about 14 per cent of all new diabetes cases globally that year.

Nearly 10 million years of healthy life were lost in 2016 due to pollution-linked diabetes, representing about 14 per cent of all years of healthy life lost due to diabetes from any cause.

According to the UN 2018 Sustainable Development Goals Report, an estimated 4.2 million people died as a result of high levels of ambient air pollution.

Also Read: Eat Walnuts to Ward off Diabetes Risk

In the study, the team analysed data from more than one million participants without a history of diabetes, who were followed for a median of eight and a half years.

They also looked at particulate matters, airborne microscopic pieces of dust, dirt, smoke, soot and liquid droplets.

Poverty-stricken countries facing a higher diabetes-pollution risk include Afghanistan, Papua New Guinea and Guyana, while richer countries such as France, Finland and Iceland experience a lower risk, the study said. (IANS)