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Air pollution can Increase Risk of Dementia in Elder Women: Study

These women were also 92 per cent more likely to develop dementia, including Alzheimer's.

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New York, Feb 1, 2017: Elderly women exposed to tiny air pollution particles may face an increased risk of dementia, including Alzheimer’s disease, a study has found.

The findings showed the fine particulate matter (PM 2.5) — coming from power and automobile plants — could invade the brain and wreak havoc in older women who live in these places.

The air quality of those places which exceeds the US Environmental Protection Agency’s standard of 81 percent were more likely to experience global cognitive decline.

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These women were also 92 per cent more likely to develop dementia, including Alzheimer’s.

“Microscopic particles generated by fossil fuels get into our body directly through the nose into the brain,” said Caleb Finch, Professor at the University of Southern California (USC).

“Cells in the brain treat these particles as invaders and react with inflammatory responses, which over the course of time, appear to exacerbate and promote Alzheimer’s disease,” Finch added.

The effects were stronger in women who had the APOE4 gene — a genetic variation that increases the risk for Alzheimer’s.

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For the general population, the risk was nearly 21 per cent, the researchers said.

The study also “provides the evidence of a critical Alzheimer’s risk gene possibly interacting with air particles to accelerate brain ageing,” said Jiu-Chiuan Chen, Associate Professor at the USC.

For the study, published in the Nature journal Translational Psychiatry, the team analysed data of 3,647 of 65- to 79-year-old women who did not have dementia.

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In another experiment, the scientists chronically exposed female mice carrying the APOE4 gene to nano-sized air pollution for 15 weeks.

The results showed that the exposure of mice to air particles damaged neurons in the hippocampus — the memory centre vulnerable to both brain ageing and Alzheimer’s disease.

-IANS

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Experts Around Globe Share Ways To Combat Air Pollution

"India needs to initiate and implement strategies to tackle the deadly air pollution. The need is to adopt an integrated approach with solutions that provide real impact." Pixabay

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The three-day workshop, organised by the North India Office of the US Embassy in collaboration with not-for-profit RTI International, is aimed at sharing the US best practices in combating air pollution to reduce emissions of fine-particulate matter and other pollutants in North India. Pixabay

Indian and American experts will chalk out strategies to combat air pollution caused by crop burning, vehicular emission and construction dust at a workshop that began, here on Thursday.

The three-day workshop, organised by the North India Office of the US Embassy in collaboration with not-for-profit RTI International, is aimed at sharing the US best practices in combating air pollution to reduce emissions of fine-particulate matter and other pollutants in North India.

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“Based on the 2016 Global Burden of Disease estimates, about 1.6 million deaths per year in India have been attributed to air pollution,” the release quoted him as saying. Pixabay

It will focus on strategies to minimise emissions, behavioural changes for accepting new alternatives, adoption of tools for estimation of emissions and air quality impacts, enhancing involvement of the private sector and the public as part of the change and developing an integrated regulatory approach.

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“India needs to initiate and implement strategies to tackle the deadly air pollution. The need is to adopt an integrated approach with solutions that provide real impact.” Pixabay

Prakash Doraiswamy, Principal Air Quality Scientist at RTI International, said several north Indian cities rank among the top 25 cities in the world with fine particle (PM 2.5) concentrations 10-17 times higher than World Health Organisation’s guidelines, as per the World Global Ambient Air Quality Database (2018).

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“Based on the 2016 Global Burden of Disease estimates, about 1.6 million deaths per year in India have been attributed to air pollution,” the release quoted him as saying.

“India needs to initiate and implement strategies to tackle the deadly air pollution. The need is to adopt an integrated approach with solutions that provide real impact,” he said.  (IANS)