Wednesday June 26, 2019

Air pollution can Increase Risk of Dementia in Elder Women: Study

These women were also 92 per cent more likely to develop dementia, including Alzheimer's.

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New York, Feb 1, 2017: Elderly women exposed to tiny air pollution particles may face an increased risk of dementia, including Alzheimer’s disease, a study has found.

The findings showed the fine particulate matter (PM 2.5) — coming from power and automobile plants — could invade the brain and wreak havoc in older women who live in these places.

The air quality of those places which exceeds the US Environmental Protection Agency’s standard of 81 percent were more likely to experience global cognitive decline.

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These women were also 92 per cent more likely to develop dementia, including Alzheimer’s.

“Microscopic particles generated by fossil fuels get into our body directly through the nose into the brain,” said Caleb Finch, Professor at the University of Southern California (USC).

“Cells in the brain treat these particles as invaders and react with inflammatory responses, which over the course of time, appear to exacerbate and promote Alzheimer’s disease,” Finch added.

The effects were stronger in women who had the APOE4 gene — a genetic variation that increases the risk for Alzheimer’s.

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For the general population, the risk was nearly 21 per cent, the researchers said.

The study also “provides the evidence of a critical Alzheimer’s risk gene possibly interacting with air particles to accelerate brain ageing,” said Jiu-Chiuan Chen, Associate Professor at the USC.

For the study, published in the Nature journal Translational Psychiatry, the team analysed data of 3,647 of 65- to 79-year-old women who did not have dementia.

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In another experiment, the scientists chronically exposed female mice carrying the APOE4 gene to nano-sized air pollution for 15 weeks.

The results showed that the exposure of mice to air particles damaged neurons in the hippocampus — the memory centre vulnerable to both brain ageing and Alzheimer’s disease.

-IANS

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Study: Air Pollution Linked to Metabolic Syndrome, Hypertension and Cardiovascular Diseases

Hypertension and metabolic syndrome are important causes of cardiovascular diseases, the researchers said

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air pollution, cardiovascular diseases, hypertension
Hypertension and metabolic syndrome are important causes of cardiovascular diseases, the researchers said. Pixabay

People who are exposed to high pollution levels are at significantly higher risk of suffering from hypertension, metabolic syndrome and heart diseases, says a new study.

In the study, published in Journal of Public Health, the researchers investigated the associations between a long-term exposure to ambient air pollution and residential distance to green spaces and major roads with the development of hypertension and metabolic syndrome components such as a high triglyceride level, reduced high-density lipoprotein cholesterol, higher blood glucose, and obesity.

Hypertension and metabolic syndrome are important causes of cardiovascular diseases, the researchers said. The study’s findings showed that air pollution levels above the median are associated with a higher risk of reduced high density lipoprotein.

air pollution, cardiovascular diseases, hypertension
The study’s findings showed that air pollution levels above the median are associated with a higher risk of reduced high density lipoprotein. VOA

Traffic-related exposure was associated with the incidence of hypertension, higher triglyceride level and reduced high-density lipoprotein cholesterol. However, the negative impact of traffic air pollutants was observed only in the participants who lived in multifamily buildings.

ALSO READ: Paris to Restrict Car Use as a Measure to Fight Against Surging Air Pollution

The researchers also found positive effects of the natural environment, and have emphasized the positive impact of such spaces on cardiovascular health.

“Our research results enable us to say that we should regulate as much as possible the living space for one person in multifamily houses, improve the noise insulation of apartments, and promote the development of green spaces in multifamily houses” said study’s lead author Agn Brazien. (IANS)