Wednesday September 19, 2018

Anaemia Drug Can Aid in Recovery After Heart Attack

However, further studies will be needed to confirm if the same benefits are seen in humans, they noted

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Drugs currently undergoing development to treat anaemia — lack of blood — could be repurposed to help prevent people with Type-2 diabetes from developing heart failure, according to a new research.

Researchers found that after a heart attack, a protein called HIF acts to help heart cells survive.

In people with diabetes, fats accumulate within the heart muscle and stop the HIF protein from becoming active. This means that a person is more likely to suffer lasting heart muscle damage, and develop heart failure after a heart attack.

“After a heart attack, people with Type-2 diabetes are more likely to develop heart failure more quickly, but we have not fully understood the reasons why that is the case,” said lead researcher Lisa Heather, research student at the University of Oxford in the UK.

“What we have shown with this research is that the metabolism of people with Type-2 diabetes means they have higher levels of fatty acids in the heart. This prevents signals going to the heart protective protein telling it to ‘kick-in’ after a heart attack,” she added.

Representational image.
Representational image. (IANS)

In the study, published in the Journal of the American College of Cardiology, the team treated diabetic rats with a drug known to activate the HIF protein, and were able to encourage the heart to recover after a heart attack.

However, these initial results suggest that several drugs known to activate HIF and currently undergoing phase-III clinical trials to treat people with anaemia, could potentially be given to people with diabetes, immediately after a heart attack in the future, the researchers said.

Also Read- Samsung Introduces New Portable SSD X5 in India

“This research in rats has not only identified the mechanism that could explain why people with Type-2 diabetes have poorer outcomes after a heart attack, but also a practical way this might be prevented,” the researchers explained.

However, further studies will be needed to confirm if the same benefits are seen in humans, they noted. (IANS)

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How The Burden of Anaemia Weighs Heavy On Women In India

Through efforts, India can reduce the effects of anaemia in women and children.

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Anaemia
Through preventative measures in a school-based programme, women and families can learn more about iron deficiency and its consequences on their health and their future children.

Today, over 51% of Indian women between the ages of fifteen to forty-nine are anaemic, according to the Global Nutrition Report in 2017. Anaemia is a common, yet neglected health issue that affects children, adolescent girls, and women in India and across the globe. In fact, over 55% of Indian women experience anaemia and it is often considered as a direct or indirect cause of maternal deaths. As a result, the government is taking preventative measures to make the country anaemia-free.

Government’s efforts to fight Anemia

Since 1975, the Indian government has purposed a goal towards fighting anaemia by providing iron-folic acid supplies to pregnant women in addition to prenatal blood tests. However, in spite of such efforts, the distribution, maintenance, and free supply are still limited due to the lack of knowledge. So, how are women surviving the efforts of this common iron deficiency?

In the state of Rajasthan, the maternal mortality rate is 445 to 100,000 births. A woman named Raj who was 21 years old and pregnant with her third child, stated her lack of knowledge about her nutrient deficiency. In fact, out of the 30 tablets of folic acid she had received, she had only taken one. When asked why she described the discomfort and nausea she felt after taking it.

Anemia
Iron deficiency anemia is a condition in which the body doesn’t have enough red blood cells to properly transport oxygen to the body’s tissues.

Ayurvedic medicine for Anaemia

Recent reports claim that traditional medicines have proven to increase the risk of Hypophosphatemia, a condition caused by low levels of phosphate. In fact, the Injectafer infusion side effects may result in individuals with hypophosphatemia may exercise severe swelling and clammy skin. Although other research suggests that women should boost their daily consumption of yogurt and ghee, they must also include pure turmeric to help balance the body’s dosha, according to Ayurvedic medicine.

Today’s Women of India

Through the voices of women in Rajasthan, Pradesh, and rural India, the next step is to redefine the current rate of anaemic patients and boost prevention in young girls before they reach pregnancy. Through preventative measures in a school-based programme, women and families can learn more about iron deficiency and its consequences on their health and their future children.

As such, it can be addressed by raising awareness, interventions, and recognizing the weakness of current strategies in prevention. Through such efforts, India can reduce the effects of anemia in women and children.

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