Wednesday January 29, 2020

Anger More Harmful Than Sadness for Older Adults, Claim Researchers

During the study, participants completed questionnaires about how angry or sad they felt

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Anger Issues
Anger Issues. Pixabay

Anger is more harmful than sadness for older adults and may lead to health complications — potentially increased inflammation which is associated with chronic illnesses like heart disease, arthritis and cancer, say researchers.

The study, published in the journal Psychology and Aging, shows that anger can lead to the development of chronic illnesses whereas sadness did not.

“Sadness may help older seniors adjust to challenges such as age-related physical and cognitive declines because it can help them disengage from goals that are no longer attainable”, said study lead author Meaghan A Barlow from the Concordia University in the US.

For the study, the researchers analysed data from 226 older adults ages 59 to 93 from Montreal, Canada and grouped participants as being in early old age (59 to 79 years old) or advanced old age (80 years or older).

During the study, participants completed questionnaires about how angry or sad they felt.

Couples have tough time understanding soft negative emotions like sadness, loneliness of each other: Study.
The researchers suggest that education and therapy might help older adults reduce anger by regulating their emotions.

The research examined whether anger and sadness contributed to inflammation, an immune response by the body to perceived threats, such as infection or tissue damage.

“We found that experiencing anger daily was related to higher levels of inflammation and chronic illness for people aged 80 or above, but not for younger seniors,” added study co-author Carsten Wrosch.

Also Read- Cyber Bullying Leads to Depression in Teenagers, Says Study

“Younger seniors may be able to use that anger as fuel to overcome life’s challenges and emerging age-related losses and that can keep them healthier”, Barlow added.

The researchers suggest that education and therapy might help older adults reduce anger by regulating their emotions or by offering better coping strategies to manage the inevitable changes that accompany ageing. (IANS)

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Researchers Identify 102 Genes Associated with Autism

It's critically important that families of children with and without autism participate in genetic studies because genetic discoveries are the primary means to understanding the molecular, cellular, and systems-level underpinnings of autism

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Autism
Researchers have discovered how a Genetic Alteration that increases the risk of developing Autism and Tourette's impairs brain communication. Pixabay

In the largest genetic sequencing study of autism spectrum disorder (ASD) to date, researchers have identified 102 genes associated with risk for autism.

The discovery shows significant progress towards teasing apart the genes associated with autism from those associated with intellectual disability and developmental delay, conditions which often overlap.

According to the World Health Organisation (WHO), one in 160 children has an autism spectrum disorder (ASD).

ASDs begin in childhood and tend to persist into adolescence and adulthood. In most cases the conditions are apparent during the first five years of life.

“This is a landmark study, both for its size and for the large international collaborative effort it required.

“With these identified genes we can begin to understand what brain changes underlie ASD and begin to consider novel treatment approaches,” said Joseph D Buxbaum, Director of the Seaver Autism Center for Research and Treatment at Icahn School of Medicine at Mount Sinai.

For the study published in the journal Cell, an international team of researchers from more than 50 sites collected and analyzed more than 35,000 participant samples, including nearly 12,000 with ASD, the largest autism sequencing cohort to date.

Autism
Families of children with autism face high physical, mental and emotional burdens, are sometimes ridiculed and even accused of child abuse, says a new study. Pixabay

Using an enhanced analytic framework to integrate both rare, inherited genetic mutations and those occurring spontaneously when the egg or sperm are formed, researchers identified the 102 genes associated with ASD risk.

Of those genes, 49 were also associated with other developmental delays.

The larger sample size of this study enabled the research team to increase the number of genes associated with ASD from 65 in 2015 to 102 today.

In addition to identifying subsets of the 102 ASD-associated genes, the researchers showed that ASD genes impact brain development or function and that both types of disruptions can result in autism.

“Through our genetic analyses, we discovered that it’s not just one major class of cells implicated in autism, but rather that many disruptions in brain development and in neuronal function can lead to autism,” said Buxbaum.

Also Read: Vaping May not Help with Smoking Cessation: Report

It’s critically important that families of children with and without autism participate in genetic studies because genetic discoveries are the primary means to understanding the molecular, cellular, and systems-level underpinnings of autism.

“We now have specific, powerful tools that help us understand those underpinnings, and new drugs will be developed based on our newfound understanding of the molecular bases of autism,” the researchers noted. (IANS)