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Researchers have found that a common antibacterial substance found in toothpaste may combat life-threatening diseases such as cystic fibrosis (CF) when combined with a drug.

The study, published in the journal Antimicrobial Agents and Chemotherapy, found that when triclosan — a substance that reduces or prevents bacteria from growing — is combined with an antibiotic called tobramycin, it kills the cells that protect the CF bacteria, known as Pseudomonas aeruginosa, by up to 99.9 per cent.


CF is a common genetic disease with one in every 2,500 to 3,500 people diagnosed with it at an early age. It results in a thick mucus in the lungs, which becomes a magnet for bacteria.

These bacteria are notoriously difficult to kill because they are protected by a slimy barrier known as a biofilm, which allows the disease to thrive even when treated with antibiotics, the researcher said.

“The problem that we’re really tackling is finding ways to kill these biofilms,” said lead author Chris Waters, Professor at the Michigan State University.


According to the researcher, there are many common biofilm-related infections that people get such as ear infections and swollen, painful gums caused by gingivitis.

But more serious, potentially fatal diseases join the ranks of CF including endocarditis, or inflammation of the heart, as well as infections from artificial hip and pacemaker implants, the researcher added.

For the study, the researchers grew 6,000 biofilms in petri dishes, added in tobramycin along with many different compounds, to see what worked better at killing the bacteria.

Also Read: Indian scientists say endosulfan damages liver, lungs, male fertility in mice

Twenty-five potential compounds were effective, but one stood out, the researcher said.

“It’s well known that triclosan, when used by itself, isn’t effective at killing Pseudomonas aeruginosa. But when I saw it listed as a possible compound to use with tobramycin, I was intrigued. We found triclosan was the one that worked every time,” said Alessandra Hunt from the Michigan State University. (IANS)


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Upcoming medical colleges in Uttar Pradesh will be named after saints and sages

The new medical colleges being opened in Uttar Pradesh will be named after saints and sages.

The state government has issued an order naming four district hospitals that are being converted into medical colleges.

These district hospitals are in Bijnor, Fatehpur, Chandauli, and Siddharth Nagar.

The Bijnor medical college has been named after Mahatma Vidur, a philosopher during the Mahabharata era and uncle of the Pandavas and Kauravas.

The Chandauli medical college has been named after Baba Keenaram, said to be the founder of the Aghori sect.

The Siddharth Nagar district hospital will be called Madhav Prasad Tripathi Medical College after the BJP politician from the region. Tripathi, popularly known as Madhav Babu, was also the first Uttar Pradesh BJP chief. He was elected MP from Domariyaganj in 1977, besides being two times Jan Sangh MLA and also a member of the UP legislative council.

The Fatehpur hospital has been named Amar Shaheed Jodha Singh Ataiya Thakur Dariyawn Singh Medical College, after the freedom fighter of 1857.

It is said that he was among the first to use Guerrilla warfare against the British, as taught by freedom fighter Tatya Tope.

Meanwhile, according to official sources, the medical college in Deoria will be named after Maharishi Devraha Baba and the medical college of Ghazipur in the name of Maharishi Vishwamitra.

The medical college of Mirzapur will be in the name of Maa Vindhyavasini, the medical college of Pratapgarh in the name of Dr. Sonelal Patel and the medical college of Etah will be named after Veerangana Avantibai Lodhi. (IANS/JB)

Keywords: Medical Colleges, Uttar Pradesh, Yogi Adityanath, India, Politics