Never miss a story

Get subscribed to our newsletter


×
Photo by Glen Carrie on Unsplash

All sweeteners caused the pathogenic gut bacteria to invade Caco-2 cells with the exception of saccharin which had no significant effect on E. coli invasion

Commonly used artificial sweeteners can cause previously healthy gut bacteria to become diseased and invade the gut wall, potentially leading to serious health issues, according to new research. The study, published in the International Journal of Molecular Sciences, is the first to show the pathogenic effects of some of the most widely-used artificial sweeteners -- saccharin, sucralose, and aspartame -- on two types of gut bacteria, E. coli (Escherichia coli) and E. faecalis (Enterococcus faecalis).

Previous studies have shown that artificial sweeteners can change the number and type of bacteria in the gut, but the new molecular research, led by academics from Anglia Ruskin University (ARU), has demonstrated that sweeteners can also make the bacteria pathogenic. It found that these pathogenic bacteria can attach themselves to, invade, and kill Caco-2 cells, which are epithelial cells that line the wall of the intestine.

Follow NewsGram on Twitter to stay updated about the World news.


"There is a lot of concern about the consumption of artificial sweeteners, with some studies showing that sweeteners can affect the layer of bacteria which support the gut, known as the gut microbiota," said Havovi Chichger, from ARU's Biomedical Science. "These changes could lead to our own gut bacteria invading and causing damage to our intestine, which can be linked to infection, sepsis, and multiple-organ failure," Chichger added.

ALSO READ: gut hormone regulating fat is abnormal in obesity

It is known that bacteria such as E. faecalis which cross the intestinal wall can enter the bloodstream and congregate in the lymph nodes, liver, and spleen, causing a number of infections including septicemia. This new study discovered that at a concentration equivalent to two cans of diet soft drink, all three artificial sweeteners significantly increased the adhesion of both E. coli and E. faecalis to intestinal Caco-2 cells, and differentially increased the formation of biofilms.

Bacteria growing in biofilms are less sensitive to antimicrobial resistance treatment and are more likely to secrete toxins and express virulence factors, which are molecules that can cause disease. Additionally, all three sweeteners caused the pathogenic gut bacteria to invade Caco-2 cells found in the wall of the intestine, with the exception of saccharin which had no significant effect on E. coli invasion, the researchers said. (IANS/JC)


Popular

Photo found on Google Images

Savitribai Khanolkar, the designer of Param Vir Chakra

Eve Yvonne Maday de Maros, the woman who designed the Param Vir Chakra, was born in 1913 in Neuchatel, Switzerland. It was believed that she came to India to understand the country's culture and tradition.

She got to know about India's spiritual and cultural wealth at a very early age through holistic education which she received. Soon, Eve Yvonne fell in love with a Maharashtrian named Vikram Khanolkar, who was a young army officer, and was undergoing training at the Royal Military Academy in the United Kingdom.

Keep Reading Show less
Photo by Adam Winger on Unsplash

The whole salon environment at home believes that services at home are undoubtedly the best option during the unusual crisis.

In this world full of technological advancement where everything is now home-delivered, even the most essential beauty services are now available at your doorstep? Let the pampering sessions begin. The whole salon environment at home believes that services at home are undoubtedly the best option during the unusual crisis.

IANSlife brings you the co-founder of YES MADAM, Mayank Arya who speaks of the benefits of at-home salon services.

Comfort
We all prefer comfort over anything and everything. Nothing is more comfortable than getting everything under your own roof. One of the most amazing perks of subscribing to an at-home salon service provider is that you can watch your favourite TV show or OTT series while having your hair treated or nails done. Amidst, Covid-19 and working from home some of the beauty services can be taken simultaneously. Getting beauty services at your home keeps you relaxed and calm. During festivals when you are already busy the on-demand salon services can do wonders for your mind, body and soul.

woman lying on sofa Nothing is more comfortable than getting everything under your own roof. | Photo by Inside Weather on Unsplash

Keep Reading Show less
Photo by Helena Lopes on Unsplash

India has been ranked 139 out of 149 countries in the list of UN World Happiness Report 2021.

By Aishwarya Jain

According to the World Happiness Report 2021 which was released by the UN Sustainable Development Solutions Network, Finland was once again crowned as the world's happiest country. India has been ranked 139 out of 149 countries in the list of UN World Happiness Report 2021. To make society happy, firstly it is really important to spread awareness on how it is okay to relax, chill and take a break. People tend to normalise overworking, which is so wrong. Of Course, we need a job to live and sustain ourselves but you shouldn't be working yourself to death, and the fact that this is seen as normal is really worrying. You spend more hours at work than you do awake at home, so if those hours are drenched in misery then sadness basically becomes the norm. A study from Gallup (2017) found that happier employees were more engaged, which resulted in improved customer relationships, and a 20 percent increase in sales.

Also, lowering down the crime level would act as a major factor towards a happy society. People who witness crimes, or come across evidence of a crime in their local area, can suffer anxiety and may feel demoralised or powerless. We should also teach them to stop judging people by materialistic things and accept everyone with all their flaws. Media plays an important role in making society happy because they have the power of reaching out to billions of people and helping them out through a solution-based approach.

woman in black shirt smiling beside woman in black shirt Media plays an important role in making society happy because they have the power of reaching out to billions of people and helping them out through a solution-based approach. | Photo by Dave Goudreau on Unsplash

Keep reading... Show less