Tuesday September 25, 2018
Home India 11 Must-Know ...

11 Must-Know Facts About Asima Chatterjee

Her publications are extensively cited and most of her work is included in several textbooks

0
//
115
Asima Chatterjee was the first Indian woman to hold a doctorate. Wikimedia Commons
Asima Chatterjee was the first Indian woman to hold a doctorate. Wikimedia Commons
Republish
Reprint

Asima Chatterjee was an organic chemist noted for her work in organic chemistry and phytomedicine. She also authored a considerable volume of work on medicinal plants, also she was the first woman to receive a Doctorate of Science from an Indian university. On 23rd September 2017 (her 100th birth anniversary), Google honoured her with a Google doodle. 

Here are 11 facts about Asima Chatterjee you must know: 

ALSO READ: 10 must-know facts about Anand Mahindra

1. Asima Chatterjee’s research primarily focused on the medicinal properties of Indian plants and contributed to developing drugs that treated epilepsy and malaria.

2. One of her most esteemed discoveries came in the field of vinca alkaloids which are used in chemotherapy today.

3. Her achievements won her many prestigious accolades including received the Shanti Swarup Bhatnagar Award (1961) and the Padma Bhushan (1975) – one of the highest civilian awards bestowed by the Indian government.

4. In 1944, she was appointed as an Honorary Lecturer in Chemistry, Calcutta University. In 1947, she worked with L.M. Parks University of Wisconsin, USA.

Calcutta University became her permanent address until her death in 2006. Wikimedia Commons
Calcutta University became her permanent address until her death in 2006. Wikimedia Commons

5. Asima Chatterjee was appointed Reader in the Department of Pure Chemistry, Calcutta University in 1954. It also became her permanent address until her death.

6. In 1962, Asima Chatterjee became the 10 Khaira Professor of Chemistry, one of the most prestigious and coveted Chairs of the Calcutta University which she adorned till 1982 and was the first woman scientist to adorn a chair of any
University in India.

7. In 1975, she became the first woman to be appointed the general president of the Indian Science Congress.

8. Asima Chatterjee also established a Regional Research Institute for carrying out research on Indian medicinal plants for the development of Ayurvedic drugs along with an Ayurvedic Hospital for systematic clinical trials through a unique Centre-State collaboration, under the aegis of the Central Council for Research in Ayurveda and Siddha in Salt Lake City, Kolkata.

ALSO READ: 12 Facts About Nain Singh Rawat

9. Asima Chatterjee developed the anti-epileptic drug, Ayush-56 from Marsilia minuta, also the anti-malarial drug from Alstonia scholaris, Swrrtia chirata, Picrorphiza kurroa and Ceasalpinna crista. These patented drugs have been marketed by several companies.

10. Chatterjee had published 400 papers in national and international journals. Her publications are extensively cited and most of her work is included in several textbooks.

11. It is said that she developed the interest in medicinal plants because of her father, Dr Indra Narayan Mukherjee, a medical man cum amateur.

Click here for reuse options!
Copyright 2018 NewsGram

Next Story

Scientists Discover A New Method To Fight Alzheimer’s, Dementia

Worldwide, about seven percent of people over 65 suffer from Alzheimer's or some form of dementia, a percentage that rises to 40 percent above the age of 85.

0
Alzheimer's
One hemisphere of a healthy brain (L) is pictured next to one hemisphere of a brain of a person suffering from Alzheimer disease. VOA
Eliminating dead-but-toxic cells occurring naturally in the brains of mice designed to mimic Alzheimer’s slowed neuron damage and memory loss associated with the disease, according to a study published Wednesday that could open a new front in the fight against dementia.The accumulation in the body of “zombie cells” that can no longer divide but still cause harm to other healthy cells, a process called senescence, is common to all mammals.

Scientists have long known that these dead-beat cells gather in regions of the brain linked to old age diseases ranging from osteoarthritis and atherosclerosis to Parkinson’s and dementia.

Prior research had also shown that the elimination of senescent cells in ageing mice extended their healthy lifespan.

But the new results, published in Nature, are the first to demonstrate a cause-and-effect link with a specific disease, Alzheimer’s, the scientists said.

Alzheimer's
A lady suffering from Alzheimer’s. Flickr

But any treatments that might emerge from the research are many years down the road, they cautioned.

In experiments, a team led by Tyler Bussian of the Mayo Clinic in Rochester, Minnesota used mice genetically modified to produce the destructive, cobweb-like tangles of tau protein that form in the neurons of Alzheimer’s patients.

The mice were also programmed to allow for the elimination of “zombie” cells in the same region.

“When senescent cells were removed, we found that the diseased animals retained the ability to form memories, and eliminated signs of inflammation,” said senior author Darren Baker, also from the Mayo Clinic.

The mice likewise failed to develop Alzheimer’s signature protein “tangles”, and retained normal brain mass.

 

Alzheimer's
Alzheimer’s disease patient Isidora Tomaz, 82, sits in an armchair in her house in Lisbon, Portugal. It’s predicted that by 2050, 135 million Americans are going to suffer from mild cognitive impairment, a precursor of Alzheimer’s. VOA

Keeping zombies at bay

A closer look revealed that the “zombies” belonged to a class of cells in the brain and spinal cord, called glia, that provide crucial support and insulation to neurons.

“Preventing the build-up of senescent glia can block the cognitive decline and neuro-degeneration normally experienced by these mice,” Jay Penney and Li-Huei Tsai, both from MIT, wrote in a comment, also in Nature.

Bussian and his team duplicated the results with pharmaceuticals, suggesting that drugs could one day slow or block the emergence of Alzheimer’s by keeping these zombie cells at bay.

“There hasn’t been a new dementia drug in 15 years, so it’s exciting to see the results of this promising study in mice,” said James Pickett, head of research at Alzheimer’s Society in London.

 

Alzheimer's
The accumulation in the body of “zombie cells” that can no longer divide but still cause harm to other healthy cells, a process called senescence, is common to all mammals. IANS

For Lawrence Rajendran, deputy director of the Dementia Research Institute at King’s College London, the findings “open up new vistas for both diagnosis and therapy for neurodegenerative diseases, including Alzheimer’s.”

Up to now, dementia research has been mostly focused on the diseased neurons rather than their neighboring cells.

“It is increasingly becoming clear that other brains cells play a defining role,” Rajendran added.

Several barriers remain before the breakthrough can be translated into a “safe, effective treatment in people,” Pickett and other said.

The elderly often have lots of harmless brain cells that look like the dangerous senescent cells a drug would target, so the molecule would have to be good at telling the two apart.

Also Read: Common Painkillers Triple Harmful Side Effects in Dementia

Worldwide, about seven percent of people over 65 suffer from Alzheimer’s or some form of dementia, a percentage that rises to 40 percent above the age of 85.

The number afflicted is expected to triple by 2050 to 152 million, according to the World Health Organization, posing a huge challenge to healthcare systems. (VOA)