Friday April 27, 2018

Asthma In Childhood Can Trigger COPD Later: Lancet

Interventions to maximise lung growth in early childhood might modify the risk of COPD in older age, they noted

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Children with asthma uses inhaler to relieve some of the symptoms. Wikimedia Commons
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While smoking remains the biggest risk factor for chronic obstructive pulmonary disease (COPD), childhood illnesses such as asthma, bronchitis, pneumonia, allergic rhinitis and eczema also amplify the disease, say researchers.

Three-quarters of COPD cases have their origins in poor lung function pathways beginning in childhood, according to a cohort study published in The Lancet Respiratory Medicine journal.

Asthma can cause severe damage to one’s lungs. VOA

A second study in the journal suggests that there could be a window of opportunity during childhood to reduce the risk of poor lung function in later life.

“These findings highlight the importance of preventing both early life adverse exposures that could lead to poorer lung growth and adult risk factors contributing to accelerated lung decline,” says Professor Shyamali Dharmage from School of Population and Global Health, The University of Melbourne, Australia. COPD is expected to be the third-largest cause of death globally by 2030. “It is important that we identify its key causes so that this burden can be reduced,” Dharmage added.

Also Read: Smoking during pregnancy linked to asthma severity in kids

Childhood asthma can trigger COPD in later life. IANS

Reduction of maternal smoke exposure and personal smoking and promotion of immunisation are identified as public health targets to prevent poor lung function pathways.

“Doctors and patients with asthma should be made aware of the potential long-term implications of non-optimal asthma control throughout life, and this should be investigated in future research,” the study authors noted. In the first study, 2,438 participants from the Tasmanian Longitudinal Health Study (Australia) were tracked from childhood to the age of 53.

In the second study, 2,632 participants were tracked from birth to 24 years old and their lung function was measured. In the second study, the authors found that around three-quarters of infants aged one to six months with poor lung function improved throughout their childhood, indicating a window of opportunity to increase lung function and potentially reduce risk of COPD in later life.

Other than chronic diseases, lifestyle habits like smoking causes cancer too. Pixabay
Earlier smoking was the most common cause of COPD. Pixabay

Interventions to maximise lung growth in early childhood might modify the risk of COPD in older age, they noted. IANS

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Smoking during pregnancy linked to asthma severity in kids

Prenatal tobacco smoke exposure was associated with a 2.5 times increase in odds of having airflow obstruction in children with asthma

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  • Smoking during pregnancy can be very dangerous
  • It can lead to asthma and poor lung function in the baby
  • It also can have serve effects on the health of the mother

Women who smoke while pregnant contribute to the severity of asthma and poor lung function in their children warns a study.

The findings published in the journal CHEST suggest that tobacco smoke exposure during pregnancy is more strongly associated with worse lung function than current, ongoing exposure in school-aged children with asthma.

Smoking during pregnancy can be unhealthy for the child.

“This study implicates maternal smoking in pregnancy as the period of second-hand exposure that is more strongly associated with worse lung function in asthmatic children,” said lead investigator Stacey-Ann Whittaker Brown from Icahn School of Medicine at Mount Sinai, New York.

“Maternal smoking in pregnancy may set children with asthma on a trajectory of poor lung function in later childhood, and other studies suggest this effect may be lifelong,” Whittaker Brown said.

Investigators analysed the relationship between lung function and the type of second-hand smoke exposure in a representative sample of school-aged children aged six to 11 years.

Also Read: Why you should avoid Paracetamol during pregnancy

The sample consisted of 2,070 children who participated in the 2007-2012 National Health and Nutrition Examination Survey (NHANES) in the US.

Detailed information about ongoing second-hand smoke exposure as well as parental self-reported exposure prior to birth was obtained.

During the study period, lung function was measured using spirometry, and exposure to smoking was assessed through levels of cotinine in the blood, a marker of the extent of current second-hand smoke exposure. Thus, investigators were able to distinguish clearly between exposure in pregnancy and ongoing second-hand smoke exposure.

Protein responsible for postpartum depression in pregnancy found
Smoking during pregnancy is very dangerous. IANS

Nearly 10 percent of both children with and without asthma in the sample had reduced lung function.

Investigators found that current tobacco smoke exposure was independently associated with airflow obstruction in school-aged children, although the extent of the association was small.

However, prenatal tobacco smoke exposure was associated with a 2.5 times increase in odds of having airflow obstruction in children with asthma, the study said. IANS