Saturday October 19, 2019

Researchers Identify Extract From Avocado Seeds Exhibiting Anti-inflammatory Properties

Avocado seed extract shows anti-inflammatory activity

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more than 80% of avocados are grown in California, where there is a drought
more than 80% of avocados are grown in California, where there is a drought. Pixabay

Researchers have identified that an extract from avocado seeds exhibited anti-inflammatory properties in a laboratory study.

The team, including Joshua Lambert from Penn State, said that it represents a potential source for novel anti-inflammatory compounds that could be developed as a functional food ingredient or pharmaceuticals.

The researchers developed the extract over the last decade as a food colourant and it is not known whether the compounds responsible for the extract’s vibrant orange colour play any role in its ability to inhibit the production of pro-inflammatory mediators, said Lambert.

To determine the anti-inflammatory properties of the avocado seed extract, the researchers used cell culture models and enzymes that are important in immune response and inflammatory diseases.

A class of immune cells called macrophages were grown in petri dishes and activated with a pro-inflammatory stimuli in the presence or absence of the avocado seed extract.

Avocado boxes are collected an avocado orchard in Michoacan, Mexico, Jan. 16, 2014.

The researchers measured the production of important pro-inflammatory mediators and signalling pathways in the cells after treatment with the extract.

“The next step, before we can draw further conclusions about the anti-inflammatory activity of this avocado seed extract, will be to design animal model studies,” Lambert explained.

Also Read- Would Elon Musk Be Able to Drive Tesla Cars in India?

“The level of activity that we see from the extract is very good. We saw inhibitory activity at concentrations in the low microgram-per-millilitre range, which is an acceptable amount of activity to justify further studies,” Lambert added.

The discovery could be important because cancer, cardiovascular diseases, arthritis, colitis and many more serious conditions are associated with chronic inflammation, suggests the study published in the journal Advances in Food Technology and Nutritional Sciences. (IANS)

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A Diet Rich in Nutrients Helps In Living Longer: Study

Anti-inflammatory foods consist of fruits and vegetables, tea, coffee, whole grain bread, breakfast cereal, low-fat cheese, olive oil.

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10th Anniversary of Eat less Meat campaign by Hindu Council Pixabay

Adhering to a diet rich in fruits, vegetables, whole grain bread, nuts, olive oil and canola oil may help you live longer, a new study has found.

The findings, published in the Journal of Internal Medicine, suggest that those who closely follow an anti-inflammatory diet have an 18 per cent lower risk of all-cause mortality.

The researchers also found that those who follow the diet experience a 20 per cent lower risk of cardiovascular mortality, and a 13 per cent lower risk of cancer mortality, when compared with those who followed the diet to a lesser degree.

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A bowl of fresh fruits a day may lower the risk of developing diabetes by 12 per cent, a study has showed. Pixabay

“Our dose-response analysis showed that even partial adherence to the anti-inflammatory diet may provide a health benefit,” said lead author Joanna Kaluza, Associate Professor at the Warsaw University of Life Sciences in Poland.

It was also found that smokers who followed the diet experienced even greater benefits when compared with smokers who did not follow the diet, the team said.

For the study, the research team involved 68,273 Swedish men and women aged between 45 and 83 years. The participants were followed for 16 years.

The anti-inflammatory potential of the diet was estimated using the validated anti-inflammatory diet index (AIDI), which includes 11 potential anti-inflammatory and five potential pro-inflammatory foods.

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The researchers also found that those who follow the diet experience a 20 per cent lower risk of cardiovascular mortality. Flickr

Anti-inflammatory foods consist of fruits and vegetables, tea, coffee, whole grain bread, breakfast cereal, low-fat cheese, olive oil and canola oil, nuts, chocolate, and moderate amounts of red wine and beer.

Also Read: Controlling Diet a Remedy For Metabolic Syndrome

Pro-inflammatory foods include unprocessed and processed red meat, organ meats, chips, and soft-drink beverages, the team said. (IANS)