Monday January 20, 2020

Maintaining A Healthy Weight And Avoiding Alcohol Can Eliminate Thousands Of Breast Cancer Cases

Together, these modifiable risk factors -- regular alcohol consumption and excessive weight gain -- will be responsible for nearly 30,000 cases of breast cancer by next decade, noted the study published in the International Journal of Cancer.

0
//
florida, hepatitis A
Florida had 65 new cases in the past two weeks alone, bringing the total to 2,034, state officials said. Pixabay

Drinking one alcoholic drink daily as well as being overweight can increase the risk of developing breast cancer, warns a study of over two lakh women.

“That means that consequently, even relatively small preventable proportions translate into large numbers of preventable breast cancers,” said Maarit Laaksonen, from the University of New South Wales in Australia.

Over the next decade, drinking alcohol will lead to 13 per cent increase of breast cancer cases in pre-menopausal women and six per cent in post-menopausal breast cancers. Being overweight or obese will contribute to 13 per cent cases.

injection
Further, the use of menopausal hormone therapy was found to account for seven per cent of post-menopausal breast cancers, with over 90 per cent of this burden caused by a long-term use. Pixabay

Together, these modifiable risk factors — regular alcohol consumption and excessive weight gain — will be responsible for nearly 30,000 cases of breast cancer by next decade, noted the study published in the International Journal of Cancer.

Further, the use of menopausal hormone therapy was found to account for seven per cent of post-menopausal breast cancers, with over 90 per cent of this burden caused by a long-term use.

bottles
Over the next decade, drinking alcohol will lead to 13 per cent increase of breast cancer cases in pre-menopausal women and six per cent in post-menopausal breast cancers. Being overweight or obese will contribute to 13 per cent cases. Pixabay

Similarly, long-term use of oral contraceptives accounted for seven per cent of pre-menopausal breast cancers.

Also Read: Fighting Has Intensified Across Many Afghan Provinces
However, it is not recommended that women restrict their use of oral contraceptives as they are actually cancer-protective and provide long-term protection against endometrial and ovarian cancers, suggesting that the potential benefits, including reproductive benefits, outweigh the harms, Laaksonen said, adding that further studies are needed to confirm the results.

Maintaining a healthy weight and not consuming alcohol regularly could help prevent thousands of breast cancer cases, he suggested. (IANS)

Next Story

Males Have Higher Risk of Suffering from Cancer: Study

Researchers explain why cancer risk is higher in males

0
Cancer
DNA differences between men and women may explain why cancer risk is higher in males. Pixabay

DNA differences between men and women may explain why cancer risk is higher in males, according to a new study.

In findings published in the Journal of the National Cancer Institute, researchers have reported that loss of function in certain genes of the sex-determining Y chromosome, which is present only in men, may cause them to have an elevated risk for cancer.

Using data from 9,000 individuals, the researchers studied Y-chromosome gene function in patients with various types of cancer. The findings showed that cancer risk increases with loss of function of six key Y-chromosome genes in various types of cells.

“Recent studies have shown that complete loss of the Y chromosome, which is essential to foetal sex differentiation, occurs, with aging, in the cells of some men,” said study author Juan Ramon Gonzalez from Barcelona Institute for Global Health in Spain.

Cancer DNA
Suppression of the Y chromosome can occur as a result of loss of function in the chromosome. Pixabay

“Although the loss of the Y chromosome has previously been associated with higher incidence of cancer, the causes of this association are poorly understood,” Gonzalez added.

These six Y-chromosome genes are involved in cell-cycle regulation, the failure of which can lead to tumour development.

According to the study, understanding the biological differences between men and women in cancer is crucial for the development of personalised lines of treatment and prevention.

“Men are not only at higher risk of cancer than women, they also face a worse prognosis. In fact, these differences partially account for the lower life expectancy of men,” Gonzalez added.

According to the researchers, although men may be more exposed to carcinogens due to the type of work they do and at higher risk because they are less likely to consult a doctor, the study has shown that there are also biological factors that increase cancer risk among men.

“In fact, it seems that one of these factors can be found in the Y chromosome, the very essence of maleness,” said study lead author Alejandro Caceres.

Also Read- Know About the Health Benefits of Green Tea

Suppression of the Y chromosome can occur as a result of loss of function in the chromosome, which would explain previous findings, or as a result of other mechanisms mediated by the chemical (epigenetic) inactivation of the same regions, the research said.

“Certain environmental exposures, for example to tobacco or other harmful substances, could affect chromosome function and lead to epigenetic modifications,” Gonzalez said. (IANS)