Saturday, January 23, 2021
Home Life Style Health & Fitness Natural Bacteria, Covid-19 Together May Increase Severity in Obese, Diabetic Patients

Natural Bacteria, Covid-19 Together May Increase Severity in Obese, Diabetic Patients

"There is rapidly emerging evidence highlighting obesity and type 2 diabetes as key risk factors linked to severity of Covid-19 infections in all ethnic groups," said study author Philipp Scherer from the University of Texas Southwestern Medical Centre

The combined effects of the body’s natural community of bacteria, also called microbiota, working together with Covid-19 in the lungs could explain the severity of the disease in people with obesity and diabetes, say researchers.

The review, published in the journal eLife, offers important mechanistic insights into why people with obesity and diabetes seem to be at increased risk of developing severe acute respiratory syndrome (SARS) after infection with the Covid-19 virus, and more often require hospitalisation and ventilation.

Follow NewsGram on Twitter to stay updated about the World news.

“There is rapidly emerging evidence highlighting obesity and type 2 diabetes as key risk factors linked to severity of Covid-19 infections in all ethnic groups,” said study author Philipp Scherer from the University of Texas Southwestern Medical Centre, Dallas in the US.

Covid-19, bacteria together may increase severity in some patients
People with obesity and diabetes seem to be at increased risk of developing severe acute respiratory syndrome (SARS) after infection with the Covid-19 virus. Unsplash

In their article, the research team revisit the factors and disease pathways that connect obesity and diabetes to the severity of Covid-19 infection.

The mechanisms can be roughly divided into two groups: those connected with the ACE2 receptor, and those providing an interaction between Covid-19 and pre-existing bacterial conditions.

ACE2 resides on the surface of many cells in the human body and is involved in regulating fluid volumes, blood pressure and the function of blood vessels. It is also used by Covid-19 to enter human cells.

Want to read more in Hindi? Checkout: स्वदेश में विकसित सिग्नल सिस्टम पर दौड़ेगी दिल्ली मेट् 

One theory is that increased amounts of ACE2 in people with obesity or diabetes makes it easier for the virus to enter cells and increases the viral load — an important factor in determining disease severity.

Alternatively, increased shedding of ACE2 in people with obesity causes it to move to the lungs, where the virus can use it.

Covid-19, bacteria together may increase severity in some patients
It is possible that these LPS molecules join forces with Covid-19 in humans and trigger a chain of events that causes healthy tissue to transform into scarred tissue. Unsplash

Another factor known to be influential in the progression of lung diseases is our body’s microbiota. We carry more than 100 trillion bacteria in our body — outnumbering the number of our own cells.

The team considered how host bacteria might influence Covid-19 severity.

Also Read: Obesity: A Dangerous Outcome of Sedentary Lifestyle Amid Pandemic

One potential culprit is the lipopolysaccharides (LPS) that bacteria produce, which have been shown to cooperate with other coronaviruses to induce SARS in pigs.

It is possible that these LPS molecules join forces with Covid-19 in humans and trigger a chain of events that causes healthy tissue to transform into scarred tissue — as Covid-19 does in the lungs.

“While all of these potential mechanisms can contribute to the severity of Covid-19, we believe that one of them plays the predominant role, and that this must be present not only in obese and diabetic patients, but also in other groups of increased risk in Covid-19,” Scherer explained. (IANS)

STAY CONNECTED

19,120FansLike
362FollowersFollow
1,773FollowersFollow

Most Popular

Your Guide To Treadmill & Walking Pad: Beginner Workout Routine

BY PEGGY Benefits Of The Treadmill & Walkingpad: Working out on the treadmill is considered to be one of the best ways to keep your body...

Study Reveals Valuing Friendships Can Keep One Healthy

Having friends in life is important as they give us both emotional support and practical advice, whenever needed. A new study now suggests that...

White House To Display The Moon Rock In Oval Office

NASA has loaned a Moon rock for display in the Oval Office of the White House at the request of the Joe Biden administration. The...

Analysis Shows Batterry Storage To Be Cheaper Than New Coal Power Plants

A new economic viability analysis on Friday revealed that renewable energy along with battery storage in Tamil Nadu is cost competitive with new coal...

Vegan kids may have low level of vitamin D

If your child is fully vegan, then there are chances that they may have a lower level of vitamin D, a new study suggests. The...

Pandemic time used for self-development, survey reveals

The pandemic year 2020 is past us but not the coronavirus and the impact it brought into our lives is probably the biggest disruption...

What And When Do You Need Estate Planning Strategies

There are estate planning strategies to reduce estate taxes. If you have assets that are exempt from the estate tax and that you intend...

Loney Adults Over The Age of 50 May Face Mental Health Problems

Lonely adults aged 50 and over reported an average of two worsening depressive and other mental health symptoms during the Covid-19 lockdown, a new...

Recent Comments