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Bimagrumab is an antibody that blocks activin type II receptors. Pixabay

Researchers have found that treatment with Bimagrumab is safe and effective for treating excess adiposity and metabolic disturbances of adult patients with obesity and Type-2 diabetes. Bimagrumab is an antibody that blocks activin type II receptors and stimulates skeletal muscle growth.

“These exciting results suggest that there may be a novel mechanism for achieving weight loss with a profound loss of body fat and an increase in lean mass, along with other metabolic benefits,” said researcher Steve Heymsfield from Pennington Biomedical Research Center, in the US.


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For the study, published in the JAMA Network Open journal, a total of 75 patients with Type-2 diabetes, body mass index between 28 and 40, and glycated hemoglobin A1c levels between 6.5 percent and 10 percent were selected for the phase 2 randomized clinical trial. Patients were injected with either Bimagrumab or a placebo (a dextrose solution) every 4 weeks for 48 weeks. Both groups received diet and exercise counseling.

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At the end of the 48-week study, researchers found a nearly 21 percent decrease in body fat in the Bimagrumab group compared to 0.5 percent in the placebo group. The results also revealed the Bimagrumab group gained 3.6 percent of lean mass compared with a loss of 0.8 percent in the placebo group. The combined loss in total body fat and gain in a lean mass led to a net 6.5 percent reduction in body weight in patients receiving Bimagrumab compared with 0.8 percent weight loss in their counterparts receiving the placebo. (IANS)


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Pakistan has failed miserably to protect Hindus, their interests.

A Hindu temple in Pakistan's Punjab province was reportedly vandalized by hundreds of people after a nine-year-old Hindu boy, who allegedly urinated at a local seminary, received bail, a media report said on Thursday.

According to the Dawn news report, the incident took place on Wednesday in Bhong town, about 60 km from Rahim Yar Khan city.

Besides the vandalization, the mob also blocked the Sukkur-Multan Motorway (M-5), the report added.

Citing sources, Dawn news said that a case was registered against the minor on July 24 based on a complaint filed by a cleric, Hafiz Muhammad Ibrahim, of the Darul Uloom Arabia Taleemul Quran.

The sources said that "some Hindu elders did tender an apology to the seminary administration saying the accused was a minor and mentally challenged".

But, when a lower court granted him bail a few days ago, some people incited the public in the town on Wednesday and got all shops there closed in protest, the report quoted the sources as further saying.

A video clip showing people wielding clubs and rods storming the temple and smashing its glass doors, windows, lights, and damaging the ceiling fans went viral on social media.

Also Read: Hindu Woman Axed To Death In Pakistan

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