Friday December 13, 2019

Blood Pressure-Lowering Effect of Exercise Significantly Reduces When People Rinse their Mouths with Mouthwash

For the study, published in the journal Free Radical Biology and Medicine, 23 healthy adults were asked to run on a treadmill

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Mouthwash, Blood Pressure, Exercise
Scientists already know that blood vessels open up during exercise, as the production of nitric oxide increases the diameter of the blood vessels (known as vasodilation), increasing blood flow circulation to active muscles. Pixabay

Researchers have found that the blood pressure-lowering effect of exercise is significantly reduced when people rinse their mouths with antibacterial mouthwash, rather than water – showing the importance of oral bacteria in cardiovascular health.

“Scientists already know that blood vessels open up during exercise, as the production of nitric oxide increases the diameter of the blood vessels (known as vasodilation), increasing blood flow circulation to active muscles,” said study lead author Raul Bescos, Professor at the University of Plymouth.

For the study, published in the journal Free Radical Biology and Medicine, 23 healthy adults were asked to run on a treadmill for a total of 30 minutes on two separate occasions, after which they were monitored for two hours.

On each occasion at one, 30, 60 and 90 minutes after exercise they were asked to rinse their mouths with a liquid – either antibacterial mouthwash (0.2 per cent chlorhexidine) or a placebo of mint-flavoured water.

Mouthwash, Blood Pressure, Exercise
Researchers have found that the blood pressure-lowering effect of exercise is significantly reduced when people rinse their mouths with antibacterial mouthwash, rather than water – showing the importance of oral bacteria in cardiovascular health. Pixabay

Their blood pressure was measured and saliva and blood samples were taken before exercise and at 120 minutes after exercise.

The study found that when participants rinsed with the placebo, the average reduction in systolic blood pressure was -5.2 mmHg at one hour after exercise.

However when participants rinsed with the antibacterial mouthwash, the average systolic blood pressure was -2.0 mmHg at the same time point.

Systolic blood pressure refers to the highest blood pressure level when the heart is squeezing and pushing the blood round the body.

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The results show that the blood pressure-lowering effect of exercise was diminished by more than 60 per cent over the first hour of recovery and totally abolished two hours after exercise when participants were given the antibacterial mouthwash.

“These findings show that nitrite synthesis by oral bacteria is hugely important in kick-starting how our bodies react to exercise over the first period of recovery, promoting lower blood pressure and greater muscle oxygenation,” said study co-author Craig Cutler from the University of Plymouth.

“In effect, it’s like oral bacteria are the ‘key’ to opening up the blood vessels. If they are removed, nitrite can’t be produced and the vessels remain in their current state,” Cutler said.

“Existing studies show that, exercise aside, antibacterial mouthwash can actually raise blood pressure under resting conditions, so this study followed up and showed the mouthwash impact on the effects of exercise,” Cutler added. (IANS)

Next Story

Women who Exercise Vigorously Face Lower Mortality Risk, Says New Study

"The best situation is to have normal heart performance during exercise and good exercise capacity," Peteiro added

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Heart
Regular exercise is highly beneficial for all patients with Heart disease regardless of age, a new study has said, adding that patients who benefited most from cardiac rehabilitation were those who started out with the greatest physical impairment. Pixabay

Women who exercise vigorously are at significantly lower risk of dying from heart disease, cancer and other causes, reveals a new study.

The study, presented at EuroEcho 2019, a scientific congress of the European Society of Cardiology (ESC), examined exercise capacity and heart function during exercise in women and their links with survival.

The study included over 4,000 adult women referred for treadmill exercise echocardiography because of known or suspected coronary artery disease.

“Exercise as much as you can. Fitness protects against death from any cause,” said study author Jesus Peteiro from University Hospital A Coruna in Spain.

For the findings, participants walked or ran on a treadmill, gradually increasing the intensity, and continuing until exhaustion.

Images of the heart were generated during the test. Fitness was defined as a maximal workload of 10 metabolic equivalents (METs), which is equal to walking fast up four flights of stairs or very fast up three flights, without stopping.

Women who achieved 10 METs or more (good exercise capacity) were compared to those achieving less than 10 METs (poor exercise capacity).

During a median follow-up of 4.6 years there were 345 cardiovascular deaths, 164 cancer deaths, and 203 deaths from other causes.

After adjusting for factors that could influence the relationship, METs were significantly associated with lower risk of death from cardiovascular disease, cancer, and other causes.

long sitting hours, prolonged sitting, damage, exercise, treatment
Regular jogging was found to be the best type of exercise. Pixabay

The annual rate of death from cardiovascular disease was nearly four times higher in women with poor, compared to good, exercise capacity (2.2 per cent versus 0.6 per cent).

Annual cancer deaths were doubled in patients with poor, compared to good, exercise capacity (0.9 per cent versus 0.4 per cent).

The annual rate of death from other causes was more than four times higher in those with poor, compared to good, exercise capacity (1.4 per cent vs 0.3 per cent).

“Good exercise capacity predicted lower risk of death from cardiovascular disease, cancer, and other causes,” Peteiro said.

The researcher noted that most study participants were middle aged or older women: the average age was 64 and 80 per cent were between 50 and 75.

“The results were the same for women over 60 and less than 60 although the group under 50 was small,” said Peteiro.

Regarding imaging of the heart, the researchers assessed function of the left ventricle (one of the heart’s pumping chambers) during the exercise test.

Patients with poor heart function during exercise had a higher probability of death from cardiovascular disease during follow-up.

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Heart function during exercise did not predict the likelihood of death from cancer or other causes.

“Looking at both examinations together, women whose heart works normally during exercise are unlikely to have a cardiovascular event. But if their exercise capacity is poor, they are still at risk of death from cancer or other causes,” Peteiro said.

“The best situation is to have normal heart performance during exercise and good exercise capacity,” Peteiro added. (IANS)