Never miss a story

Get subscribed to our newsletter


×
In a pilot study, the researchers took blood test samples from 90 breast cancer patients at the time they were diagnosed with Breast Cancer and matched them with samples taken from 90 patients without breast cancer (the control group). Pixabay

Researchers have found that a simple Blood Test can detect Breast Cancer up to five years before there are any clinical signs of it.

The blood test identifies the body’s immune response to substances produced by tumour cells, according to the research presented at the 2019 NCRI (National Cancer Research Institute) Cancer Conference in Glasgow, UK, on Sunday.


“We need to develop and further validate this test,” said Daniyah Alfattani from University of Nottingham in Britain.

“However, these results are encouraging and indicate that it’s possible to detect a signal for early breast cancer. Once we have improved the accuracy of the test, then it opens the possibility of using a simple blood test to improve early detection of the disease,” she said.

Cancer cells produce proteins called antigens that trigger the body to make antibodies against them — auto-antibodies.

The researchers have found that these tumour-associated antigens (TAAs) are good indicators of cancer, and now they have developed panels of tumour-associated antigens that are known already to be associated with breast cancer to detect whether or not there are auto-antibodies against them in blood samples taken from patients.


Researchers have found that a simple blood test can detect Breast Cancer up to five years before there are any clinical signs of it. Pixabay

In a pilot study, the researchers took blood samples from 90 breast cancer patients at the time they were diagnosed with breast cancer and matched them with samples taken from 90 patients without breast cancer (the control group).

They used screening technology (protein microarray) that allowed them to screen the blood samples rapidly for the presence of auto-antibodies against 40 tumour-associated antigens associated with breast cancer, and also 27 tumour-associated antigens that were not known to be linked with the disease.

“The results of our study showed that breast cancer does induce autoantibodies against panels of specific tumour-associated antigens. We were able to detect cancer with reasonable accuracy by identifying these auto-antibodies in the blood,” Alfattani said while presenting the research.

The researchers identified three panels of tumour-associated antigens against which to test for autoantibodies. The accuracy of the test improved in the panels that contained more tumour-associated antigens.

The panel of five tumour-associated antigens correctly detected breast cancer in 29 per cent of the samples from the cancer patients and correctly identified 84 per cent of the control samples as being cancer-free.


However, these Blood Test Results are encouraging and indicate that it’s possible to detect a signal for early Breast Cancer. Pixabay

The panel of seven tumour-associated antigens correctly identified cancer in 35 per cent of cancer samples and no cancer in 79 per cent of control samples. The panel of nine antigens correctly identified cancer in 37 per cent of cancer samples and no cancer in 79 per cent of the controls.

The researchers are now testing samples from 800 patients against a panel of nine tumour-associated antigens, and they expect the accuracy of the test to improve with these larger numbers.

ALSO READ: Qualcomm’s Biz Practices Drove us Out of Chip Market, Claims Intel

“A blood test for early breast cancer detection would be cost effective, which would be of particular value in low and middle income countries. It would also be an easier screening method to implement compared to current methods, such as mammography,” said Alfattani. (IANS)


Popular

Rawpixel

Comforting Christmas cocktails help you enjoy the celebrations and get into the festive spirit.

By Olivia Sarkar
It's the holiday season, which means it's time to be merry! As the month of December approaches, we're all in a festive mindset. With Christmas just around the corner, there will be plenty of parties and get-togethers with friends and family.

Comforting Christmas cocktails help you enjoy the celebrations and get into the festive spirit. The Leela Palaces, Hotels, and Resorts offer distinctive cocktails ranging from Hot Toddies to Decadent Egg Nogs. Sit back and enjoy one martini at a time to make the festive season a little brighter.

Dirty Chai Eggnog:

Eggnog is a Christmas favorite that is accustomed to toasts for good health and prosperity. It is an American tradition that has spread around the world. Historically, it has been made using eggs, milk, and alcohol. Our culinary artists have given an Indian twist to this winter drink, making it quintessentially desi!



Recipe:

30 ml Bourbon
30 ml Baileys
90 ml Hot milk tea
Whole Spices
Sweet cream foam to top up

Garnish:
Cinnamon powder and star anise.

Keep Reading Show less
Unsplash

For the study, the team involved a small yet significant number of participants who took a probiotic capsule twice a day for six days and then took two days off. They then repeated the cycle.

Probiotics may significantly improve the symptoms of pregnancy-related nausea, vomiting and constipation, finds a new study.

The study, published in the journal Nutrients, showed that nausea hours (the number of hours participants felt nauseous) were reduced by 16 per cent, and the number of times they vomited was reduced by 33 per cent.

Keep Reading Show less