Wednesday, October 21, 2020
Home Life Style Health & Fitness Blood Test Can Detect Breast Cancer 5 Years Earlier: Study

Blood Test Can Detect Breast Cancer 5 Years Earlier: Study

The researchers are now testing samples from 800 patients against a panel of nine tumour-associated antigens, and they expect the accuracy of the test to improve with these larger numbers

Researchers have found that a simple Blood Test can detect Breast Cancer up to five years before there are any clinical signs of it.

The blood test identifies the body’s immune response to substances produced by tumour cells, according to the research presented at the 2019 NCRI (National Cancer Research Institute) Cancer Conference in Glasgow, UK, on Sunday.

“We need to develop and further validate this test,” said Daniyah Alfattani from University of Nottingham in Britain.

“However, these results are encouraging and indicate that it’s possible to detect a signal for early breast cancer. Once we have improved the accuracy of the test, then it opens the possibility of using a simple blood test to improve early detection of the disease,” she said.

Cancer cells produce proteins called antigens that trigger the body to make antibodies against them — auto-antibodies.

The researchers have found that these tumour-associated antigens (TAAs) are good indicators of cancer, and now they have developed panels of tumour-associated antigens that are known already to be associated with breast cancer to detect whether or not there are auto-antibodies against them in blood samples taken from patients.

Blood Test
Researchers have found that a simple blood test can detect Breast Cancer up to five years before there are any clinical signs of it. Pixabay

In a pilot study, the researchers took blood samples from 90 breast cancer patients at the time they were diagnosed with breast cancer and matched them with samples taken from 90 patients without breast cancer (the control group).

They used screening technology (protein microarray) that allowed them to screen the blood samples rapidly for the presence of auto-antibodies against 40 tumour-associated antigens associated with breast cancer, and also 27 tumour-associated antigens that were not known to be linked with the disease.

“The results of our study showed that breast cancer does induce autoantibodies against panels of specific tumour-associated antigens. We were able to detect cancer with reasonable accuracy by identifying these auto-antibodies in the blood,” Alfattani said while presenting the research.

The researchers identified three panels of tumour-associated antigens against which to test for autoantibodies. The accuracy of the test improved in the panels that contained more tumour-associated antigens.

The panel of five tumour-associated antigens correctly detected breast cancer in 29 per cent of the samples from the cancer patients and correctly identified 84 per cent of the control samples as being cancer-free.

Blood Test
However, these Blood Test Results are encouraging and indicate that it’s possible to detect a signal for early Breast Cancer. Pixabay

The panel of seven tumour-associated antigens correctly identified cancer in 35 per cent of cancer samples and no cancer in 79 per cent of control samples. The panel of nine antigens correctly identified cancer in 37 per cent of cancer samples and no cancer in 79 per cent of the controls.

The researchers are now testing samples from 800 patients against a panel of nine tumour-associated antigens, and they expect the accuracy of the test to improve with these larger numbers.

ALSO READ: Qualcomm’s Biz Practices Drove us Out of Chip Market, Claims Intel

“A blood test for early breast cancer detection would be cost effective, which would be of particular value in low and middle income countries. It would also be an easier screening method to implement compared to current methods, such as mammography,” said Alfattani. (IANS)

STAY CONNECTED

19,120FansLike
362FollowersFollow
1,781FollowersFollow

Most Popular

COVID-19 Can Lead to Infertility in Men, says Study

COVID-19 can cause male infertility by harming the testicular cells which produce sperms thereby making it difficult to make the female pregnant, says a...

Fashion Trends to Look Your Best in this Festive Season

It's a time to pause, to relook, to rethink - It's the time to revive the spirits. This year festivities will not be like...

Perfect Hairstyle Tips for the Festive Celebrations

It's Durga Puja time! It's the most awaited period of the year for many of us. And if you are among the ones who...

Proper Ventilation Key Factor to Prevent COVID Spread

New research adds to the growing body of evidence that effective or proper indoor ventilation may be a key factor in preventing the spread...

The 21-Day Immunity Plan To Follow: Book Review

With 80 percent of chronic disease attributable to lifestyle and linked environmental factors and within the lifestyle hierarchy, poor diet being the most important...

Tattoos May Impair Natural Sweating and Cause Overheat of Body

Researchers have found that tattoos may impair natural sweating, potentially causing the body to overheat if the tattoos cover a large area of the...

Amazon Allowing Work From Home Untill June 2021

Amazon is allowing its corporate employees to avail of the work from home option, if their roles permit, till June 2021. Amazon had earlier said...

Netflix Has Much Work to Do in Indian Market

Content streaming giant Netflix which reported slow growth in its third-quarter (July-September period) despite the social distancing times admitted that it has much work...

Recent Comments