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Bbisphosphonates is a class of drugs that prevent the loss of bone density and used to treat osteoporosis. Pixabay

Researchers have found that — bisphosphonates — a class of drugs that prevent the loss of bone density and used to treat osteoporosis and similar diseases, appear to be safe and beneficial for osteoarthritis patients.

Osteoarthritis (OA) is the most common form of arthritis and a leading cause of disability worldwide with more than 300 million sufferings with the condition, yet there are no effective treatments to stop the disease or its progression.


According to the study, published in the journal Osteoarthritis and Cartilage, one of the lesions in OA that causes pain and progression of the structural pathology of the disease is bone marrow lesions.

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“The results suggest that bisphosphonates do not appear to be harmful, at least over one year, and perhaps may even help decrease bone marrow lesions in those that have them,” said study researcher Tuhina Neogi from the Boston University in the US.

Researchers believe bisphosphonates may alter bone marrow lesions, and thereby could improve pain in OA and halt its progression. Alternatively, they could also alter the mechanical properties of bone, thereby potentially contributing to detrimental effects.


Researchers believe bisphosphonates may alter bone marrow lesions, and thereby could improve pain in OA and halt its progression. Wikimedia Commons

Using data from the Osteoarthritis Initiative, a longitudinal cohort of people with or at risk for knee OA, the researchers identified women who started bisphosphonates and matched them to women who weren’t on the drug. Measurements in bone marrow lesion volume were taken when they first started on bisphosphonate and then a year later.

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Changes in bone marrow lesion volume between the two groups were then compared.”When we looked at those who had bone marrow lesions at baseline, we found that the women who started bisphosphonates had had more bone marrow lesions that decreased in size than the women who did not start bisphosphonates,” Neogi explained.

According to the researchers, effective treatments for osteoarthritis are desperately needed.

“By examining existing data for potential signals of efficacy and safety, we can identify potentially promising therapies that should be further tested in trials with the aim to ameliorate the pain of osteoarthritis and improve the quality of life for the millions of people worldwide that have this disease,” Neogi noted. (IANS)


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Snapdeal co-founder and COO Rohit Bansal on Friday lauded a man who facilitated 64 registrations for the vaccine on the CoWin portal.

Even as India celebrates reaching a milestone of 100 crore Covid vaccine doses, Snapdeal co-founder and COO Rohit Bansal on Friday lauded a man who facilitated 64 registrations for the vaccine on the CoWin portal. In a video shared on his Facebook and Twitter page, Bansal hailed Sonu Kumar as a "citizen celebrity".

Bansal said that Kumar not only helped "just co-workers and family but complete strangers too. With patience, empathy and uncanny jugaad". He added that Kumar joined him "many moons ago" and completed his open school from a parking lot.

"Education has helped this wonderful man enable others to get India back on track. Bravo! The CoWin portal on Thursday mentioned that a total of 100 crore vaccine doses has been administered so far to the eligible population under the vaccination drive in India, nine months after the nationwide inoculation programme was started to protect the people against Covid-19.

"It's a cause of significant celebration and happiness," Bansal said in the video. He said that while people just help a few around them, Kumar "bridged the digital gap" for 64 people, who were finding it difficult to register themselves online on the vaccine portal. Kumar said he doesn't feel that he has contributed much towards the 100 crore vaccine dose count. "I have been able to help only 64 people, if I was able to help more I would have been happier." (IANS/ MBI)


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A health worker counts antiretroviral drug tablets for a patient at The AIDS Support Organization (TASO) in the capital Kampala, Uganda, July 12, 2012.

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Prepare for the special celebrations this festive season with the ultimate beauty well-being checklist which will not only make you look good on the outside but also shine from the inside.

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After the long dull period of the pandemic and lockdowns, one must be looking forward to the festival season with new excitement and zest. So obviously you want to look and feel your best. Beauty regimes are not just skin deep, they de-stress and uplift your spirits. Prepare for the special celebrations this festive season with the ultimate beauty well-being checklist which will not only make you look good on the outside but also shine from the inside.

Rachit Gupta, Director, OxyGlow Cosmetics Pvt. Ltd, said, "Festivals are a time to shine bright and invest in a proper beauty well-being regime from head to toe. The key is to know what ingredients suit you and choose the brand which ensures good quality products. Especially in the day and time when there is so much stress, pollution, sun damage, etc. One cannot go wrong with the beauty product that they are using. The right products can unleash one's true beauty and make them refreshed to be able to enjoy the festivities fully."

* Headturner -- How your hair looks to make a lot of difference to your complete look. But do not forget a proper hair care regime can relax and clear your mind. Start with a good oil massage which provides nourishment to the hair and scalp. It throws the stress right out. Coconut oil, Amla oil, Argan oil and Red onion oil are especially recommended. Special occasions call for special treatment, after a good hair wash deep condition your hair with a mask. A Keratin hair mask works wonders by putting life into your hair. Finish up with a vitamin-enriched serum for lustrous hair.

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