Higher levels of Vitamin D among women may reduce their risk of developing breast cancer post menopause, claimed a new study.
The study found that women with blood levels of serum 25-hydroxyvitamin D (OH) — the main form of vitamin D in blood — above 60 ng/ml (nanograms per millilitre) had one-fifth the risk of breast cancer compared to those with less than 20 ng/ml.
Thus, researchers from the University of California-San Diego determined that the minimum healthy level of 25(OH) in blood plasma should be 60 ng/ml, instead of the earlier recommended higher than the 20 ng/ml.
“Increasing Vitamin D blood levels substantially above 20 ng/ml appears to be important for the prevention of breast cancer,” said lead author Sharon McDonnell from GrassrootsHealth, a non-profit public health research organisation.
The study, published in the journal PLOS ONE, analysed data from two randomised clinical trials with 3,325 combined women and a prospective study involving 1,713 women with average age of 63.
Participants were free of cancer at enrollment and were followed for a mean period of four years. Vitamin D levels in blood were measured during study visits.
“This study was limited to postmenopausal breast cancer. Further research is needed on whether high 25(OH)D levels might prevent premenopausal breast cancer,” said Cedric F. Garland from UC-San Diego. (IANS.)
A woman under 40, with no known breast cancer risk or visible symptoms of the deadly disease, need not take regular mammography tests, say health experts.
Accordingto the US Centers for Disease Control and Prevention (CDC), a mammogram is an X-ray picture of the breast, used as a screening tool for the detection of early breast cancer in asymptomatic women.
“If a woman doesn’t have symptoms of breast cancer then regular mammography tests before the age of 40 are not recommended,” Ramesh Sarin, Senior Consultant (Surgical Oncology) at Indraprastha Apollo Hospitals, New Delhi, told IANS.
If there is any lump in the breast, then mammography should be done.
“Those with increased risk (which is decided by clinician analysing multiple parameters) can begin screening at a younger age around 25-30 years,” added Upasna Saxena, Consultant (Radiation Oncology) from HCG Cancer Centre in Mumbai.
In mammography, each breast is examined separately and compressed against the film to obtain maximum visualisation of masses or calcifications.
“This helps identify masses or lumps that are smaller than the size that can be felt on examination. Hence, they help in early detection of breast cancers. But at the same time all masses seen on mammography are not cancerous,” Saxena informed.
However, there are various concerns that mammography can be risky due to radiation. But experts noted that mammography uses low energy to take X-Ray of the breast.
“There are no risks which are associated with mammography, even if a woman gets 20-30 mammograms done in her lifetime,” Sarin said.
At the same time, “mammography is to be avoided in pregnant women as the foetus will be at risk even with minimal doses”.
“If at all required in a pregnant woman, it can be done using a lead shield over the abdomen,” Saxena stressed.
Breast cancer is the most common type of cancer which affects women in India and, by 2026 the country will witness rise in the breast cancer incidence to 35 per 100,000 women as compared to the present rate of 25.8 per cent, says a Confederation of Indian Industry (CII) 2018 report titled “Breast Cancer Landscape in India”.
The cancer burden in India has more than doubled over the last 26 years, the highest increase among all therapy areas, with breast cancer being the most common among Indian women.
However, the National Family Health Survey (NFHS-4) data shows only 9.8 per cent women between the age of 15 and 49 in India have ever undergone breast examination.
“Mammogram should be supplemented with monthly breast self-examination or breast awareness,” Saxena said, adding that breast self-examination once a month should start by the age of 20 onwards.
The experts also recommended MRI, ultrasonography or a biopsy in which breast tissue or fluid is removed for laboratory testing, for younger women.
“However, these alternatives are not as sensitive as mammography, wherein physical examinations can detect breast cancer only in 60-70 percent of the cases. But mammography can detect breast cancer with 85 per cent accuracy,” Sarin noted. (IANS)