Monday January 20, 2020

Cancer Linked With Internal Bleeding After Heart Attack

Bleeding during the first six months after discharge from hospital for a heart attack is linked with a subsequent cancer diagnosis

0
//
Heart attack, internal bleeding Cancer
Cancer could be the reason behind internal bleeding after Heart attack. Pixabay

Bleeding during the first six months after discharge from hospital for a heart attack is linked with a subsequent cancer diagnosis, a new study said.

“Our results suggest that patients should seek medical advice if they experience bleeding after discharge.

“Particularly if the bleeding is of gastrointestinal, pulmonary or genitourinary origin, without any obvious reason, and occurs in the first six months. If the cause is cancer, early detection can improve prognosis,” said study author Isabel Munoz Pousa from Alvaro Cunqueiro Hospital in Spain.

Following the discharge for an acute coronary syndrome — heart attack or unstable angina — patients are typically treated with dual antiplatelet therapy for around one year.

This treatment inhibits the formation of blood clots but raises the risk of bleeding.

internal bleeding, Heart Disease, Heart Failure
The median time from bleeding to cancer was 4.6 months. The link with cancer increased as the severity of bleeding worsened. Pixabay

For the study, the researchers retrospectively reviewed the hospital records of 3,644 acute coronary syndrome patients discharged with dual antiplatelet therapy from Alvaro Cunqueiro Hospital.

Patients were followed-up for a median of 56.2 months for bleeding events and cancer.

The researchers analysed associations between bleeding and the absolute risk of a new cancer diagnosis.

Bleeding occurred in 1,215 patients — 33 per cent during follow-up and 227 patients (6 per cent) had a new diagnosis of cancer.

ALSO READ: Early Onset of Menstruation Associated with Higher Risk of Diabetes

After adjustment for factors known to influence bleeding or cancer, post-discharge bleeding was associated with a threefold higher risk of a new cancer diagnosis.

The median time from bleeding to cancer was 4.6 months. The link with cancer increased as the severity of bleeding worsened.

Spontaneous bleeding with no apparent cause was linked with four times higher risk of a cancer diagnosis.

“Most of the bleeding episodes in the study were mild. The bleeding events more strongly related with a new cancer diagnosis were severe haemorrhages of unknown cause requiring surgery — for example digestive bleeding needing endoscopic treatment,” Pousa said.

The study was presented at the ESC Congress 2019 in Paris on August 31. (IANS)

Next Story

Diabetes is an Independent Risk Factor For Heart Failure: Study

According to health expert in India, if poorly controlled, diabetes leads to cardiomyopathy resulting in progressive deterioration of pumping capacity of heart

0
Diabetes
The study shows that diabetes is an independent risk factor for the development of heart failure in the community dwelling population. Pixabay

Heart problems are a common development for people with diabetes and now researchers have found that diabetes is an independent risk factor for the development of heart failure in the community dwelling population.

According to health expert in India, if poorly controlled, diabetes leads to cardiomyopathy resulting in progressive deterioration of pumping capacity of heart.

“Diabetes is also a major risk factor for atherosclerosis and this eventually leads to blockage of coronary arteries. This leads to heart attack or myocardial infarction,” Satish Koul, HOD and Director Internal Medicine, Narayana Superspeciality Hospital, Gurugram, told IANS. “Due to myocardial infarction, the heart muscle becomes weak and eventually heart fails as a pump leading to congestive heart failure,” Koul added.

According to the current study, published in the journal Mayo Clinic Proceedings, researchers evaluated the long-term impact of diabetes on the development of heart failure, both with preserved ejection fraction – a measurement of the percentage of blood leaving the heart with each contraction – and reduced ejection fraction. They also looked at mortality in a community population, controlling for hypertension, coronary artery disease and diastolic function.

From an initial group of 2,042 residents of Olmsted County in US, 116 study participants with diabetes were matched 1:2 for age, hypertension, sex, coronary artery disease and diastolic dysfunction to 232 participants without diabetes.

Over the 10-year follow-up period, 21 per cent of participants with diabetes developed heart failure, independent of other causes.

Diabetes
Heart problems are a common development for people with diabetes and now researchers have found that diabetes is an independent risk factor for the development of heart failure in the community dwelling population. Pixabay

In comparison, only 12 per cent of patients without diabetes developed heart failure. Cardiac death, heart attack and stroke were not statistically different in the study between the two groups.

The study shows that diabetes is an independent risk factor for the development of heart failure in the community dwelling population. Furthermore, the outcome data support the concept of a diabetic cardiomyopathy.

ALSO READ: India’s Domestic Air Passenger Traffic Rose 3.74% in 2019: Report

This research extends previous findings and demonstrates that even without a known cardiac structural abnormality and with a normal ejection fraction, diabetic patients are still at increased risk of developing heart failure as compared to their nondiabetic counterparts. (IANS)