Wednesday January 29, 2020

Cancer Patients Are More Prone To Death From A Stroke: Study

One explanation for the increased risk could be that many people who are diagnosed with cancer are in a 'prothrombotic' state, which means they are more likely to form a blood clot

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Stroke
Additionally, they found that among those diagnosed with Cancer before they turned 40, most Stroke occurred in people treated for brain tumors and lymphomas. Pixabay

People living with Cancer are more than twice as likely to die of a stroke, compared to the general population say researchers, adding that the risk increases with time.

Cancers of the breast, prostate or colorectum were the type most commonly associated with fatal stroke, said the study published in the journal Nature Communications.

According the researchers, previous research has shown that most cancer patients aren’t going to die of their cancer, they are going to die of something else.

“A stroke is one possibility. Our findings suggest that patients may benefit from a screening program to help prevent some of these early deaths from stroke, as well as help identify which patients we could target with those preventative efforts,” said study researcher Nicholas Zaorsky, Assistant Professor at Penn State University in the US.

For the findings, the researchers used data gathered from the National Cancer Institute’s Surveillance, Epidemiology and End Results (SEER) programme.

SEER includes data about cancer incidence, survival, treatment and age and year of diagnosis, and covers 28 per cent of the US population.

They used SEER data on more than 7.2 million patients who had been diagnosed with invasive cancer — cancer that has spread beyond the tissue in which it originally developed — between 1992 and 2015.

The researchers found that out of 7,529,481 cancer patients, 80,513 died of a stroke.

Males and females had equal chances of dying from a stroke, but those diagnosed with cancer at a younger age had a higher chance of a fatal stroke.

Stroke
People living with Cancer are more than twice as likely to die of a Stroke, compared to the general population say researchers, adding that the risk increases with time. Pixabay

Additionally, they found that among those diagnosed with cancer before they turned 40, most strokes occurred in people treated for brain tumors and lymphomas.

In patients diagnosed with cancer above the age of 40, fatal strokes were most commonly associated with cancer of the prostate, breast and colorectum.

One explanation for the increased risk could be that many people who are diagnosed with cancer are in a ‘prothrombotic’ state, which means they are more likely to form a blood clot, Zaorsky said.

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“That blood clot may then go to the lungs and cause a pulmonary embolism, for example, or cause a stroke if it goes to the brain,” Zaorsky added.

The researchers added that future studies could help pinpoint mechanisms and further establish the relationship between cancer and strokes. (IANS)

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Here’s how Consuming High Fibre Diet Leads to Bloating

People who consume high fibre diets may experience bloating

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high fibre diets bloating
People who eat high fibre diets are more likely to experience bloating if their high fibre diet is protein-rich. Pixabay

People who eat high fibre diets are more likely to experience bloating if their high fibre diet is protein-rich as compared to carbohydrate-rich, according to a new study.

For the study, published in the journal Clinical and Translational Gastroenterology, the researchers from Johns Hopkins University analysed data from a clinical trial of high fibre diets.

“It’s possible that in this study, the protein-rich version of the diet caused more bloating because it caused more of a healthy shift in the composition of the microbiome,” said study co-senior author Noel Mueller from Johns Hopkins University in the US.

high fibre diets bloating
“It’s possible that in this study, the protein-rich version of the diet caused more bloating because it caused more of a healthy shift in the composition of the microbiome. Pixabay

“Notably, the protein in these diets was mostly from vegetable sources such as beans, legumes, and nuts,” Mueller added.

High-fibre diets are believed to cause bloating by boosting certain populations of healthful fibre-digesting gut bacteria species, which produce gas as a byproduct.

The findings thus also hint at a role for “macronutrients” such as carbs and proteins in modifying the gut bacteria population–the microbiome.

In the study, the researchers examined a dietary clinical trial that was conducted in 2003 and 2005 in Boston.

Known as the Optimal Macronutrient Intake Trial to Prevent Heart Disease (OmniHeart), it included 164 participants who had above-normal blood pressure.

They were assigned to three different diets over consecutive six-week periods separated by two-week “washout” intervals during which participants returned to regular eating habits.

high fibre diets bloating
High-fibre diets are believed to cause bloating by boosting certain populations of healthful fibre-digesting gut bacteria species, which produce gas as a byproduct. Pixabay

The diets were all considered high-fibre, low-sodium “DASH” diets, and had the same number of calories, but varied in their macronutrient emphases: a carbohydrate-rich version was, by calories, 58 per cent carbohydrate, 15 per cent protein, and 27 per cent fat; a plant-protein-rich version was 48 per cent carbs, 25 per cent protein, 27 per cent fat; and a fat-rich version was 48 per cent carbohydrate, 15 per cent protein, and 37 per cent fat.

The primary results of the OmniHeart trial, published in 2005, suggested that the plant-protein-rich and fat-rich diets were the most effective in reducing blood pressure and improving measures of blood cholesterol.

In their new analysis of this data, they examined how participants’ reports of bloating–which were among the secondary data collected in that trial–varied as participants ate the three OmniHeart diets.

A key finding was that the prevalence of bloating went from 18 per cent before the diets to 24, 33, and 30 per cent, respectively, on the carb-, protein-, and fat-rich diets–indicating that these high fibre diets did indeed appear to increase bloating.

Also Read- Eating Walnuts May Help Slow Cognitive Decline: Study

The researchers also analysed the relative changes among the diets, and linked the protein-rich diet to a significantly greater chance of bloating–roughly 40 percent greater–in comparison with the carb-rich diet.

The results suggest that substituting high quality carb calories, such as whole grain, for protein calories might reduce bloating for those on high fiber diets, making such diets more tolerable. (IANS)