Sunday March 24, 2019

Cancer: Salient Features of The Killer Disease

There are more than 100 types of cancers; any part of the body can be affected

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Previous research has shown that obesity and high-fat diets both together and independently increase the risk of pancreatic cancer.
The actress was diagnosed with cancer earlier this year. Pixabay

* Cancer is a leading cause of death worldwide, accounting for 7.6 million deaths.

* India has nearly 3 million cancer patients.

* A million new cases are reported in India every year.

* Deaths from cancer worldwide are estimated to reach 13.1 million deaths in 2030.

* Lung and oral cancer is the most common among men.

Cancer
Representational image. Pixabay

* Cervix and breast cancer is the most common among women.

* Tobacco use is the most important risk factor for cancer causing 22 percent of global cancer deaths and 71 percent of global lung cancer deaths.

* Lung, stomach, liver, colon and breast cancer cause the most cancer deaths each
year.

* Cancers such as breast, cervical and colorectal cancer can be cured if detected early and treated properly.

Also Read: Outdoor Jobs Carry Different Risks of Skin Cancer

* There are more than 100 types of cancers; any part of the body can be affected.

* One-fifth of all cancers worldwide are caused by a chronic infection; for example human papillomavirus (HPV) causes cervical cancer and the hepatitis B virus (HBV) causes liver cancer. (IANS)

Next Story

Researchers Discover Balance of Two Enzymes That May Help Treat Pancreatic Cancer

While still in the earliest stages, Newton hoped this information might one day aid pancreatic diagnostics and treatment

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Cancer
Cancer Ribbon. Pixabay

A new research has set the stage for clinicians to potentially use levels of a pancreatic cancer patient’s PHLPP1 and PKC enzymes as a prognostic and for researchers to develop new therapeutic drugs that change the balance of the two enzymes as a means to treat the disease.

The study, published on Wednesday in Molecular Cell, was led by Alexandra Newton, professor in the Department of Pharmacology at the University of California, San Diego, School of Medicine, and Timothy Baffi, a graduate student in her lab, Xinhua news agency reported.

The new study built on the team’s work in 2015 that found the enzyme PKC, which was believed in previous studies to promote tumour growth, actually suppressed it.

The latest study took the investigation a step further by uncovering how cells regulate PKC activity and discovered that any time an over-active PKC is inadvertently produced, the PHLPP1 “proofreader” tags it for destruction.

Cancer patient
Cancer patient.

“That means the amount of PHLPP1 in your cells determines your amount of PKC,” Newton said. “And it turns out those enzyme levels are especially important in pancreatic cancer.”

The team observed 105 pancreatic cancer tumours to analyze the enzyme levels in each one. About 50 per cent of patients with low PHLPP1/high PKC lived longer than five-and-a-half years.

Also Read- A Brain Circuit Can Help Reverse Craving for Liquor, Says Study

While still in the earliest stages, Newton hoped this information might one day aid pancreatic diagnostics and treatment.

Pancreatic cancer is caused by the abnormal and uncontrolled growth of cells in the pancreas, a large gland in the digestive system. It typically doesn’t show symptoms in the early stages. Sufferers tend to develop signs, such as back pain and jaundice, when it has spread to other organs. (IANS)