Sunday December 15, 2019

All Women Can Be Screened For Cancer!

Screening all women over 30 years age for breast and ovarian cancer gene mutations can be cost effective, says a study

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The new approach, showed that it is cost-effective, and as a result can ensure that more women can take preventative action to reduce their risk or undertake regular screening. Pixabay
  • A study found out screening all women for cancer can be cost effective
  • The study was led by an Indian-origin researcher
  • The study was published in the Journal of the National Cancer Institute

Screening all women over 30 years age for breast and ovarian cancer gene mutations can be cost effective and could also prevent more of these cancers than just screening those at genetic high-risk, suggests a study led by an Indian-origin researcher.

The most well-known breast and ovarian cancer causing genes are BRCA1 and BRCA2, and women carrying either of the gene mutation have approximately a 17-44 per cent chance of developing ovarian cancer and a 69-72 per cent chance of developing breast cancer over their lifetime.

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Conversely, for women who do not carry these mutations, the risk is two per cent for ovarian cancer and 12 per cent for breast cancer over their life time. Pixabay
Conversely, for women who do not carry these mutations, the risk is two per cent for ovarian cancer and 12 per cent for breast cancer over their life time. Pixabay

The current clinical approach to genetic testing is based on having a personal or family history of breast or ovarian cancer.

The new approach, published in the Journal of the National Cancer Institute, showed that it is cost-effective, and as a result can ensure that more women can take preventative action to reduce their risk or undertake regular screening and thus can provide huge new opportunities for cancer prevention and changes in the way how cancer genetic testing is delivered.

“Our findings support the concept of broadening genetic testing for breast and ovarian cancer genes across the entire population, beyond just the current criteria-based approach,” said Ranjit Manchanda, Consultant Gynaecological Oncologist, at the Queen Mary University of London.

According to the World Health Organization, out of the 8.8 million deaths overall cancer deaths worldwide in 2015, breast cancer accounted for 571,000 deaths. Pixabay
According to the World Health Organization, out of the 8.8 million deaths overall cancer deaths worldwide in 2015, breast cancer accounted for 571,000 deaths. Pixabay

“Our analysis shows that population testing is the most cost-effective strategy and can have important implications given the effective options that are available for ovarian and breast cancer risk management and prevention for women at increased risk,” added Rosa Legood, Associate Professor at the London School of Hygiene and Tropical Medicine.

Furthermore, the researchers found that implementing a programme to test all British women over 30 years age could result in 17,000 fewer ovarian cancers and 64,000 fewer breast cancers.

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Ovarian cancer, with the lowest survival rate of all gynaecological cancers, is diagnosed annually in nearly a quarter of a million women globally and is responsible for 140,000 deaths each year. (IANS)

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WHO Urges South-East Asian Countries to Accelerate Efforts to Eliminate Cervical Cancer by 2030

Cervical cancer is a significant public health problem in the region

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Cancer, cells, metabolism, research, treatment, science
the workings of a metabolic pathway or "gauge" that lets cancer cells detect when they have enough nutrients around them to grow.. Pixabay

The World Health Organization (WHO) on Friday urged South-East Asian countries to accelerate efforts to eliminate cervical cancer by 2030.

“Countries need to expand vaccination, screening, detection and treatment services for everyone, everywhere to address the growing problem of cervical cancer,” said Poonam Khetrapal Singh, Regional Director WHO South-East Asia at the 72nd session of the WHO Regional Committee here in Delhi.

Cervical cancer is a significant public health problem in the region.

In 2018, an estimated 158,000 new cases and 95,766 deaths were reported due to cervical cancer, which is the third most common type of cancer.

WHO, Efforts, Cervical Cancer
The World Health Organization (WHO) on Friday urged South-East Asian countries to accelerate efforts to eliminate cervical cancer by 2030. Pixabay

Addressing cancer risk factors and reducing its prevalence has been a regional flagship priority since 2014, and all countries in the region are taking measures for screening and treatment of pre-cancers, WHO said in a statement.

According to the WHO, four countries in the Region – Bhutan, Maldives, Sri Lanka and Thailand – have introduced HPV vaccines nationally.

“We need to scale up both our capacities and quality for screening, treatment services and palliative care,” Singh said.

Vaccination against human papillomavirus, screening and treatment of pre-cancer, early detection and prompt treatment of early invasive cancers and palliative care are proven effective strategies to address cervical cancer.

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Member countries are working towards interim global targets – of achieving 90 per cent girls fully vaccinated with the human papilloma virus (HPV) vaccine by 15 years of age; having 70 per cent women screened with a high-precision test at 35 and 45 years of age: and of 90 per cent women identified with the cervical disease receiving treatment and care by 2030.

The WHO South-East Asia Regional Director said there is a need to strengthen national cervical cancer control plans, including appropriate strategies and guidelines for immunisation, screening, treatment and care, including palliative care.

WHO is prioritising cervical cancer elimination as worldwide cervical cancer remains one of the gravest threats to women’s lives. (IANS)