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Cardiology Society of India urges Patients with blockages of Coronary Arteries to try latest Interventional Heart Technologies

FFR and OCT are innovative tools that enable doctors for accurate diagnosis and deciding the right treatment strategy for the patient

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Research bodies estimate that the number of fragments of dead cells in the bloodstream increase with higher levels of pollution. Pixabay

New Delhi, May 31, 2017: Aiming to replicate the latest interventional heart technologies, the Cardiology Society of India on Wednesday urged patients with blockages of coronary arteries to undergo Fractional Flow Reserve (FFR) and Optical Coherence Tomography (OCT) as these help in better assessment for stent placement.

The new technique FFR measures the blood flow volume in the blocked artery and provides an assessment of the severity of a coronary artery lesion, while OCT provides a high quality image of the inside of coronary arteries to determine the anatomical characteristics of the vessel.

FFR and OCT are innovative tools that enable doctors for accurate diagnosis and deciding the right treatment strategy for the patient.

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“The integration of these technologies are also immensely beneficial for the patients as they primarily help in scientifically assessing and perfecting the treatment decision for the patient, resulting in long term clinical benefits,” said M.S. Hiremath, President, Cardiology Society of India, in a statement.

He said that the two techniques can contribute to more transparency in decision making and deciding whether stent placement is necessary and if stent is implanted optimally or not.

“FFR helps the cardiologist with a readily available technique for evaluating the seriousness of the blockage and take accurate decisions. This has a positive effect on patient outcomes and quality of life post treatment while OCT has high resolution and speed, giving clear views of the vessel blockage which can help in deciding upon the course of treatment,” he said.

According to national health statistics, of the 30 million heart patients in India, 14 million reside in urban areas and 16 million in rural areas. Cardiac hospitals in India perform over 2,00,000 open heart surgeries per year — one of the highest, worldwide.

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Doctors have sought a upgradation of quality of treatment in India, as globally, technology is changing. The next-generation technologies are helping physicians in making accurate treatment decisions.

“The advantages of the two techniques is that these guarantee correct blockages are identified and treated, which further helps in improved stent placement leading to better patient outcomes,” said Praveen Chandra, Chairman of Interventional Cardiology, Medanta – The Medicity, Gurugram. (IANS)

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New Sleeping Pill Can Help Patients Wake up in Response to Threat

However, more studies on humans are needed to confirm DORA safety and efficacy, they noted

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Pills (representational Image), Pixabay

Japanese scientists have shown that a new class of sleeping pill that preserves the ability to wake in response to a threat, unlike the commonly prescribed drugs that muffles a sleeping brain’s “intruder alert”.

Even during sleep the brain continuously processes sensory information, waking us if it detects a threat. But the most widely prescribed class of sleeping pills, known as benzodiazepines, makes us less likely to rouse in response to sensory input.

The findings showed that millions prescribed on these sleeping pills would sleep through a fire alarm as someone vacuuming next to their bed.

 However, the new class of drugs called dual orexin receptor antagonists (DORAs) more selectively targeted the brain’s sleep or wake pathways, which gives them safety advantages over benzodiazepines, said researchers from the Kagoshima University.

These include a reduced “hangover effect”, with DORAs less likely to affect driving ability the day after use.

“Benzodiazepines stimulate the widespread brain receptor GABA-A, which makes us sleepy but also suppresses off-target brain areas – including the ‘gatekeeper’ that decides which sensory inputs to process,” explained author Tomoyuki Kuwaki, Professor at the varsity.

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New sleeping pill can help patients wake up in response to threat.

In the study, published in Frontiers in Behavioral Neuroscience journal, mice that were given the new experimental hypnotic drug DORA-22 wake as quickly when threatened as drug-free sleepers — and then fall back asleep as quickly as ones given standard sleeping pills, once the threat is gone.

While DORA-22 allows mice to wake to a threat, it still helps them sleep.

Thus, the selectivity of DORAs could make them a safer alternative during sleep as well — by allowing the brain’s sensory gatekeeper to stay vigilant to threats, the researchers said.

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However, more studies on humans are needed to confirm DORA safety and efficacy, they noted.

“Although it remains to be seen whether DORAs have the same properties when used in humans, our study provides important and promising insight into the safety of these hypnotics,” Kuwaki said. (IANS)