Wednesday September 19, 2018
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Cellphone-based tech could cut lab visits for blood tests

The portable MELISA weighs less than half a kg, and the researchers believe that it has the potential help older patients suffering chronic conditions and those across the world

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Blood Tests now available on mobile phones.
Blood Tests now available on mobile phones.
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  • Researchers have developed a cellphone-based blood test
  • This can save visits to doctors
  • The technology is called Enzyme-Linked Immunosorbent Assay (ELISA)

Researchers have developed a cellphone-based blood test technology that can provide immediate results in the comfort of one’s home or a doctor’s clinic, thereby cutting visits to the laboratory.

In a paper published in the journal Biosensors and Bioelectronics, the researchers detailed a mobile version of the “Enzyme Linked Immunosorbent Assay” (ELISA), the gold standard technique used to detect the presence of an antibody or antigen.

This test will save visits to the hospital. Pixabay

“ELISA is an important technology for biochemical analysis of proteins and hormones and is critical for the diagnosis of many diseases, such as HIV and Lyme Disease,” said corresponding author Anna Pyayt, Assistant Professor at the University of South Florida in Tampa, US.

“But the machines required for the incubation and reading are expensive and bulky,” Pyayt said. Instead of sending patients to a laboratory, the new cellphone-based technology – Mobile Enzyme Linked Immunosorbent Assay (MELISA) — allows for the very same test to be conducted in the doctor’s office, clinic or even in a remote area.

Also Read: Blood sodium levels linked to cognition in older adults

“The MELISA allows patients to undergo testing and obtain results at point-of-care,” Pyayt said. The device accurately measures progesterone levels, a key hormone that impacts female fertility and is indicative of some cancers.

It consists of a water bath heater that incubates samples at a target temperature and analyses them via images taken by mobile phone. The device uses colour analysis to determine the RGB (red, green, blue) colour components of each sample. The blue colour component is used for further analysis due to its sensitivity to the changes in progesterone concentration.

blood type
Thi is a revolutionary invention. Pixabay

“It is designed to make biomedical testing simple and affordable. When low cost testing can be integrated with routine clinic visits, this would greatly improve the quality of healthcare and detect worrisome signs earlier,” Pyayt added. The portable MELISA weighs less than half a kg, and the researchers believe that it has the potential help older patients suffering chronic conditions and those across the world. IANS

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Heart Attack Patients Get Safer, Faster Lab Scores That Diagnose Diseases

Within one month of the emergency department visits, 727 heart attacks or deaths in patients occurred.

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Faster, safer lab score to diagnose heart attacks developed. Pexels

Researchers have developed a simple laboratory score which is safer and faster at diagnosing patients who visit the emergency department with heart attack symptoms.

The findings, published in the CMAJ (Canadian Medical Association Journal), suggest that the score can also identify patients at risk of subsequent heart issues after discharge.

“We have developed a simple lab score that is superior to using cardiac troponin alone for the identification of patients at low and high risk for heart attack or death at emergency department presentation,” said co-author Peter Kavsak from the McMaster University in Ontario, Canada.

“This lab score may reduce both the number of blood tests and the time spent in the emergency department for chest pain patients,” Andrew Worster, Professor at the varsity, said.

The team combined common laboratory blood tests available at several hospitals around the world to create a single laboratory score. Pixabay
The team combined common laboratory blood tests available at several hospitals around the world to create a single laboratory score. Pixabay

For the study, the team combined common laboratory blood tests available at several hospitals around the world to create a single laboratory score or clinical chemistry score, to diagnose a heart attack.

These blood tests are part of the World Health Organization’s (WHO) list of essential in vitro diagnostic tests for health care facilities with clinical laboratories.

The researchers validated the clinical chemistry score as a predictor of heart attacks or deaths within 30 days, using the data on 4,245 patients from emergency department studies in four countries — Canada, Australia, New Zealand, and Germany.

Within one month of the emergency department visits, 727 heart attacks or deaths in patients occurred.

blood tests are part of the World Health Organization's (WHO) list of essential in vitro diagnostic tests for health care facilities with clinical laboratories.
blood tests are part of the World Health Organization’s (WHO) list of essential in vitro diagnostic tests for health care facilities with clinical laboratories. Pixabay

A negative (or low-risk) clinical chemistry score at emergency department presentation missed only one of these events compared with up to 25 missed heart attacks or deaths when using a high-sensitivity cardiac troponin test alone.

Also Read: Microsoft, Apollo Hospitals to use AI for Cardiac Diseases

A positive (or high-risk) clinical chemistry score also identified about 75 per cent of the patients at high risk of heart attacks or deaths when positive compared with a low of 40 per cent detected when the high-sensitivity cardiac troponin test alone was positive.

The researchers suggest the score can be useful for standardising diagnoses and improving safety. (IANS)