Tuesday May 22, 2018
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Cellphone-based tech could cut lab visits for blood tests

The portable MELISA weighs less than half a kg, and the researchers believe that it has the potential help older patients suffering chronic conditions and those across the world

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Blood Tests now available on mobile phones.
Blood Tests now available on mobile phones.
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  • Researchers have developed a cellphone-based blood test
  • This can save visits to doctors
  • The technology is called Enzyme-Linked Immunosorbent Assay (ELISA)

Researchers have developed a cellphone-based blood test technology that can provide immediate results in the comfort of one’s home or a doctor’s clinic, thereby cutting visits to the laboratory.

In a paper published in the journal Biosensors and Bioelectronics, the researchers detailed a mobile version of the “Enzyme Linked Immunosorbent Assay” (ELISA), the gold standard technique used to detect the presence of an antibody or antigen.

This test will save visits to the hospital. Pixabay

“ELISA is an important technology for biochemical analysis of proteins and hormones and is critical for the diagnosis of many diseases, such as HIV and Lyme Disease,” said corresponding author Anna Pyayt, Assistant Professor at the University of South Florida in Tampa, US.

“But the machines required for the incubation and reading are expensive and bulky,” Pyayt said. Instead of sending patients to a laboratory, the new cellphone-based technology – Mobile Enzyme Linked Immunosorbent Assay (MELISA) — allows for the very same test to be conducted in the doctor’s office, clinic or even in a remote area.

Also Read: Blood sodium levels linked to cognition in older adults

“The MELISA allows patients to undergo testing and obtain results at point-of-care,” Pyayt said. The device accurately measures progesterone levels, a key hormone that impacts female fertility and is indicative of some cancers.

It consists of a water bath heater that incubates samples at a target temperature and analyses them via images taken by mobile phone. The device uses colour analysis to determine the RGB (red, green, blue) colour components of each sample. The blue colour component is used for further analysis due to its sensitivity to the changes in progesterone concentration.

blood type
Thi is a revolutionary invention. Pixabay

“It is designed to make biomedical testing simple and affordable. When low cost testing can be integrated with routine clinic visits, this would greatly improve the quality of healthcare and detect worrisome signs earlier,” Pyayt added. The portable MELISA weighs less than half a kg, and the researchers believe that it has the potential help older patients suffering chronic conditions and those across the world. IANS

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Newly Developed Tool to Battle HIV in Women

This novel tool may soon help women to combat HIV transmission

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HIV Aids is a deadly disease.
HIV AIDS

Scientists have developed a new tool that can potentially help protect women from being infected with the human immunodeficiency virus (HIV).

The tool — a vaginal implant — decreases the number of cells that the HIV virus can target in a woman’s genital tract.

Unlike conventional methods of HIV prevention such as condoms or anti-HIV drugs, the novel implant takes advantage of some people’s natural immunity to the virus.

The deadly disease of HIV is now preventable.
HIV is now preventable.

HIV infects the body by corrupting T-cells that are mobilised by the immune system when the virus enters a person’s body.

“We know that some drugs taken orally never make it to the vaginal tract, so this implant could provide a more reliable way to encourage T-cells not to respond to infection and therefore more reliably and cheaply prevent transmission,” said Emmanuel Ho, professor at the University of Waterloo in Canada.

When the T-cells stay resting and do not attempt to fight the virus they are not infected and the HIV virus is not transmitted between people.

When the T-cells stay resting, it is referred to as being immune quiescent.

However, “what we don’t know yet is if this can be a stand-alone option for preventing HIV transmission or if it might be best used in conjunction with other prevention strategies”, Ho added, in a paper appearing in the Journal of Controlled Release.

Also Read: Severe Symptoms Of Menopause Might Soar The Risk Of Heart Diseases In Women

The implant is composed of a hollow tube and two pliable arms to hold it in place.

It contains hydroxychloroquine (HCQ) which is disseminated slowly through the porous material of the tube and absorbed by the walls of the vaginal tract.

The implants were tested in an animal model and a significant reduction in T-cell activation was observed, meaning that the vaginal tract was demonstrating an immune quiescent state, the researchers said.  IANS

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