Monday April 22, 2019

Childhood Maltreatment Strongest Risk Factor for Depression in Adulthood: Lancet

The findings are to develop or improve risk-adapted interventions for people susceptible to a worse long-term clinical outcome

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Fourteen had a remission period of less than two months and could therefore be regarded as having chronic depression. Pixabay

Facing trauma in childhood can significantly change the structure of the brain, which may result in severe depression which could even be recurrent in adulthood, say researchers.

The results from MRI scan images suggest that both childhood maltreatment and recurring depression are associated with similar reductions in the surface area of the insular cortex, part of the brain that regulates emotion and self-awareness.

This reduction in the brain could make a future relapse more likely, said the study, published in The Lancet Psychiatry journal, which found childhood maltreatment one of the strongest risk factors for major depression in adulthood.

depression
Depression is among the leading causes of disability in the U.S. and is being closely monitored by health authorities amid rising suicides nationwide. Pixabay

“Given the impact of the insular cortex on brain functions such as emotional awareness, it’s possible that the changes we saw make patients less responsive to conventional treatments,” said lead researcher Nils Opel from the University of Munster in Germany.

The study included 110 patients aged 18 to 60 years. Of the 75 patients who experienced a relapse, 48 had experienced one additional episode, seven reported two episodes, and six experienced three episodes.

Fourteen had a remission period of less than two months and could therefore be regarded as having chronic depression.

depression
This reduction in the brain could make a future relapse more likely, said the study, published in The Lancet Psychiatry journal. Pixabay

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The findings are to develop or improve risk-adapted interventions for people susceptible to a worse long-term clinical outcome.

Future psychiatric research should therefore explore how the findings could be translated into special attention, care and treatment that could improve patient outcomes, the study noted. (IANS)

Next Story

Violent Relationships Can Increase The Risk Of Mental Disorder in Women

However, a certain amount of unpredictability was actually healthier for women, noted researchers.

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depression
For the study, the researchers included 120 women participants, who were assessed concerning the abusive behaviour they faced and the violent environment around them. Pixabay

Women, please take note. If you are in a violent relationship you may be at an increased risk of suffering from mental disorders, suggests a new study.

The study, published in Primary Care Companion for CNS Disorders journal, indicates that the unpredictable violence not only causes physical injuries to women but also leaves the victims at a higher risk of suffering from mental disorders.

relationship
For the study, the researchers included 120 women participants, who were assessed concerning the abusive behaviour they faced and the violent environment around them. Pixabay

“We expect severity and frequency to be the major driver to patient outcomes, but in some cases it isn’t,” said David Katerndahl, Professor at the University of Texas Health Science Center, US.

“The nonlinearity, or unpredictability, of the violence is much more of a driver,” he added.

depression
The study, published in Primary Care Companion for CNS Disorders journal, indicates that the unpredictable violence not only causes physical injuries to women but also leaves the victims at a higher risk of suffering from mental disorders. Pixabay

However, a certain amount of unpredictability was actually healthier for women, noted researchers.
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“Women who have what we call ‘optimal nonlinearity’, which means they have some nonlinearity but it’s not extreme, actually did better in the study in general,” said Katerndahl.

For the study, the researchers included 120 women participants, who were assessed concerning the abusive behaviour they faced and the violent environment around them. (IANS)