Tuesday September 17, 2019

Children with Mild Asthma can Effectively Manage Condition by Using Two Inhalers

Patients in the group that used both inhalers as needed used about one-fourth the steroid dose of the group that inhaled a prescribed daily amount

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Children, Mild, Asthma
The steroid inhaler lowers inflammation and the bronchodilator, also known as a rescue inhaler, relaxes the airway during an asthma attack to quickly make breathing easier, according to the study published. Pixabay

Researchers have found that children with mild asthma can effectively manage the condition by using their two inhalers — one a steroid and the other a bronchodilator — when symptoms occur.

The steroid inhaler lowers inflammation and the bronchodilator, also known as a rescue inhaler, relaxes the airway during an asthma attack to quickly make breathing easier, according to the study published in the Journal of Allergy and Clinical Immunology: In Practice.

“Patients in the group that used both inhalers as needed used about one-fourth the steroid dose of the group that inhaled a prescribed daily amount. We also were pleased to see that the patients and families felt that they had more ownership over their asthma management when practicing as-needed treatment,” said study first author Kaharu Sumino, Associate Professor at the Washington University.

The researchers found that this approach reduced the amount of steroid medication the children took monthly by almost 75 per cent.

Children, Mild, Asthma
Researchers have found that children with mild asthma can effectively manage the condition by using their two inhalers — one a steroid and the other a bronchodilator — when symptoms occur. Pixabay

The study included 206 African American children six to 17 years of age with mild asthma that was adequately controlled with asthma controller steroid medication. The patients were randomly assigned to one of two groups.

Each participant in one group was advised to take a dose from an inhaler containing the steroid beclomethasone as needed when symptoms arose, along with the rescue bronchodilator albuterol.

Each participant in the second group was advised to take a specific inhaled dose of the steroid beclomethasone daily, regardless of symptoms, plus the rescue bronchodilator as needed in response to symptoms.oo

At the end of the one-year study, the researchers found no differences between groups in surveys of how well the patients’ asthma was controlled, as well as no differences in breathing tests that measure lung function.

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However, the group taking daily beclomethasone, an inhaled corticosteroid, used more of the medication per month than those in the symptom-based group.

On average, children in the daily-use group used 1,961 micrograms per month, while the symptom-based group used 526 micrograms per month, cutting the amount of this medication by almost three-fourths. The reduced amount is desirable, according to the investigators, because steroids have side effects that include stunted growth. (IANS)

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Gavi Appealing for $7.4 Billion to Immunize 300 Million Children in 2021-25

Gavi’s latest fundraising drive is its most ambitious to date

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Gavi, Immunize, Children
FILE - A child is vaccinated against Ebola in Beni, Democratic Republic of the Congo, July 13, 2019. VOA

Gavi, the global vaccine alliance that targets developing countries, said Friday that it was appealing for $7.4 billion to immunize 300 million children in 2021-25.

Gavi’s latest fundraising drive is its most ambitious to date. Officials said they expected huge returns from what would be the agency’s most comprehensive and cost-effective preventive health package ever.

Gavi said the vaccines would protect against 18 diseases, saving up to 8 million lives. Spokeswoman Frederique Tissandier said sustainable investment was needed for the project because there still are 1.5 million people dying every year from vaccine-preventable diseases.

“The situation is increasingly fragile because of climate change, because of wars, because of the rise of the population in the urban slums,” she said. “So you have more and more epidemics that are spreading around.”

Gavi, Immunize, Children
Gavi, the global vaccine alliance that targets developing countries, said Friday that it was appealing for $7.4 billion to immunize 300 million children in 2021-25. Pixabay

Tissandier said Gavi planned to introduce new vaccines to prevent deadly diseases. For instance, she said, Gavi is ready to invest up to $150 million in a new Ebola vaccine stockpile once it is prequalified by the World Health Organization.

She told VOA that Gavi also would help the Democratic Republic of the Congo obtain the lifesaving vaccines it needs to immunize children against other killer diseases.

“We are going to fund, for instance, starting in September, measles campaigns in DRC to cover — I think the number is close to 18 million kids — to strengthen routine immunization, because we really focus on routine immunization,” Tissandier said. “We fund the stockpile against cholera, yellow fever or meningitis to respond to outbreaks.”

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She said support for the global polio eradication program remained a priority. Tissandier said Gavi would invest up to $800 million to accelerate the rollout of inactivated poliovirus vaccine. This would protect against a re-emergence of the disease in areas such as Africa, which is on the cusp of becoming polio-free, and other regions that already have achieved that status. (VOA)