Friday February 28, 2020

Children of Mothers With Diabetes Are Likely To Suffer From Heart Diseases, Says Study

The researchers also found higher rates for specific types of CVD children of mothers with diabetes

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Diabetes
Diabetes was categorised as pregestational (before pregnancy) or gestational (during pregnancy) and women with diabetic complications were identified in the Study. Pixabay

Children of mothers with diabetes have increased rates of early onset cardiovascular disease or CVD (conditions affecting the heart or blood vessels) from childhood up to the age of 40, the researchers have warned.

The increased rates were more pronounced among children of mothers with a history of CVD or diabetic complications, said the study published in the journal The BMJ.

“Our study provides evidence that children of mothers with diabetes, especially those with a history of CVD or with diabetic complications, had increased rates of early onset CVD throughout the early decades of life,” said study researchers from Aarhus University in Denmark.

If this association is shown to be causal, preventing, screening, and treating diabetes in women of childbearing age could be important not only for improving the health of the women but also for reducing long term risks of CVD in their offspring, the researchers added

The number of women diagnosed with diabetes before or during pregnancy has increased globally, and children of these women are more likely to have risk factors for future CVD, such as high blood pressure and high blood sugar levels. It is unclear, however, whether or to what extent exposure to diabetes in the womb increases the risk of developing CVD in offspring over a lifetime.

So an international team of researchers set out to evaluate associations between diabetes diagnosed before or during pregnancy and early onset CVD in children during their first four decades of life. They base their findings on national registry data for over 2.4 million children born without congenital heart disease in Denmark from 1977 to 2016.

Diabetes was categorised as pregestational (before pregnancy) or gestational (during pregnancy) and women with diabetic complications were identified.

Diabetes
Children of mothers with diabetes have increased rates of early onset cardiovascular disease or CVD (conditions affecting the heart or blood vessels) from childhood up to the age of 40, the researchers have warned. Pixabay

Other potentially influential factors, such as mother’s age, education, lifestyle and medical history were also taken into account. During up to 40 years of follow-up, children of mothers with diabetes had a 29 per cent increased overall rate of early onset CVD compared with children of mothers who did not have diabetes (cumulative risks: 17.8 per cent vs 13.1 per cent ).

The researchers also found higher rates for specific types of CVD children of mothers with diabetes, particularly heart failure (45 per cent), hypertensive disease (78 per cent), deep vein thrombosis (82 per cent), and pulmonary embolism (91 per cent).

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Increased rates were seen in each age group in childhood (before 20 years of age) and early adulthood (from 20 to 40 years of age), regardless of the type of diabetes they were exposed to (pregestational or gestational) and rates were similar for both type 1 and type 2 diabetes, the study said. (IANS)

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Air Pollution Increases Risk of Developing Kidney Diseases

India may face kidney diseases due to air pollution

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Kidney disease pollution
People living in countries with higher levels of air pollution such as India and China may face higher risks of developing kidney diseases. Pixabay

Researchers have found that people living in countries with higher levels of air pollution such as India and China may face higher risks of developing kidney diseases.

The findings may be especially important for parts of the world with higher air pollution where fine particulate matter levels are five to 10 times higher than in the US, the study said.

It’s known that breathing in air pollution can have detrimental health effects beyond the lungs, but few studies have shown how it impacts the kidneys, which act as filters for the blood.

“As rates of chronic kidney disease rise worldwide, it is important to understand whether and how exposure to air pollution plays a role,” said study researcher Matthew F. Blum from the Johns Hopkins University in the US.

Kidney disease pollution
It’s known that breathing in air pollution can have detrimental health effects beyond the lungs, but few studies have shown how it impacts the kidneys, which act as filters for the blood. Pixabay

For the findings, published in the Clinical Journal of the American Society of Nephrology, the research team examined information on 10,997 adults across four sites in the US who were followed from 1996-1998 through 2016.

The researchers estimated the monthly average levels of tiny particles of air pollution–called fine particulate matter–based on participants’ home addresses.

Fine particulate matter comes from a variety of sources including fossil fuel combustion, industrial processes, and natural sources, they said.

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The team found that exposure to higher amounts of fine particulate matter was associated with a higher degree of albuminuria — a marker of kidney dysfunction — at the start of the study as well as a higher risk of developing chronic kidney disease over time.

According to the researchers, future studies should examine whether efforts to improve air quality yield health benefits, including reducing rates of chronic kidney disease. (IANS)