Wednesday September 19, 2018

Coffee can predict Parkinson’s disease

The team involved 108 people who had Parkinson's disease for an average of about six years and 31 people of the same age who did not have the disease and consumed about two cups of coffee per day

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Parkinson’s disease is named after Dr James Parkinson (1755-1824), the doctor that first identified the condition. Wikimedia commons
Parkinson’s disease is named after Dr James Parkinson (1755-1824), the doctor that first identified the condition. Wikimedia commons
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A neurodegenerative disorder which leads to progressive deterioration of motor function due to loss of dopamine-producing brain cells. Yes, that’s Parkinson’s disease. Quite horrifying, isn’t it?

However, there maybe a chance of predicting it.

The way your body metabolises your cup of coffee each morning may determine your chances of developing Parkinson’s disease.

The reason that Parkinson’s disease develops is not known. Wikimedia commons
The reason that Parkinson’s disease develops is not known. Wikimedia commons

Findings

  • People with Parkinson’s disease had significantly lower levels of caffeine in their blood than people without the disease, even if they consumed the same amount of caffeine.
  • Thus, testing the level of caffeine in the blood may provide a simple way to aid the diagnosis of Parkinson’s disease, the researchers said.

“Previous studies have shown a link between caffeine and a lower risk of developing Parkinson’s disease, but we haven’t known much about how caffeine metabolises within the people with the disease,” said Shinji Saiki, MD at the Juntendo University School of Medicine in Tokyo.

“If these results can be confirmed, they would point to an easy test for early diagnosis of Parkinson’s, possibly even before symptoms are appearing,” added David G. Munoz, MD, at the University of Toronto.

“This is important because Parkinson’s disease is difficult to diagnose, especially at the early stages,” Munoz noted.

The main symptoms of Parkinson’s disease are tremor, slowness of movement (bradykinesia) and muscle stiffness or rigidity. Wikimedia commons
The main symptoms of Parkinson’s disease are tremor, slowness of movement (bradykinesia) and muscle stiffness or rigidity. Wikimedia commons

Methodology

  • The team involved 108 people who had Parkinson’s disease for an average of about six years and 31 people of the same age who did not have the disease and consumed about two cups of coffee per day.
  • Their blood was tested for caffeine and for 11 byproducts the body makes as it metabolises caffeine. They were also tested for mutations in genes that can affect caffeine metabolism.
  • The caffeine level was an average of 79 picomoles per 10 microliters for people without Parkinson’s disease, compared to 24 picomoles per 10 microliters for people with the disease.
  • However, there were no differences found in the caffeine-related genes between the two groups.

The study was published in journal Neurology. (IANS)

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Next Story

Coffee Can Reduce Fatality Rate For People Suffering From Chronic Kidney Disease

For the study, described in the journal Nephrology Dialysis Transplantation, the team involved data from 4,863 people.

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Coffee beans, chronic kidney disease
Coffee may prolong lifespan for people with kidney disease. VOA

Drinking coffee may help reduce the risk of death for people with chronic kidney disease, suggests a study.

Comparing with people that consumed less caffeine, patients that consumed higher levels of caffeine presented a nearly 25% reduction in the risk of death over a median follow-up of 60 months.

The possible protective effect of caffeine might be related with effects at vascular level as caffeine is known to promote the release of substances, such as nitric oxide, that improve the function of the vessel, the researchers said.

chronic kidney disease
Kidney disease. IANS

“Our study showed a protective effect of caffeine consumption among patients with chronic kidney disease. The reduction in mortality was present even after considering other important factors such as age, gender, race, smoking, other diseases, and diet,” said lead author Miguel Bigotte Vieira from the Centro Hospitalar Lisboa Norte in Portugal.

“These results suggest that advising patients with kidney disease to drink more caffeine may reduce their mortality. This would represent a simple, clinically beneficial, and inexpensive option,” Vieira added.

For the study, described in the journal Nephrology Dialysis Transplantation, the team involved data from 4,863 people.

Also Read: Smelling Coffee May Boost Your Analytical Skills

However, the researchers emphasised that this observational study cannot prove that caffeine reduces the risk of death in patients with chronic kidney disease, but only suggests the possibility of such a protective effect. (IANS)