Saturday August 18, 2018

Common Plastic Chemical May Increase Breast Cancer Risk

Most breast cancers are estrogen receptor positive, and, according to the National Cancer Institute, 55 to 65 per cent of women who inherit a harmful mutation in the BRCA1 gene -- will develop breast cancer

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Bisphenol S (BPS), a substitute for the chemical bisphenol A (BPA) in the plastic industry, acts like estrogen in multiplying breast cancer cells.
Bisphenol S (BPS), a substitute for the chemical bisphenol A (BPA) in the plastic industry, acts like estrogen in multiplying breast cancer cells. Pixabay
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An endocrine-disrupting chemical commonly found in polycarbonate hard plastics, currency bills and thermal paper receipts may potentially interfere with the body’s hormones to increase the aggressiveness of breast cancer, a new study has showed.

Bisphenol S (BPS), a substitute for the chemical bisphenol A (BPA) in the plastic industry, acts like estrogen in multiplying breast cancer cells.

Most breast cancers are estrogen receptor positive, and, according to the National Cancer Institute, 55 to 65 per cent of women who inherit a harmful mutation in the BRCA1 gene — will develop breast cancer.

“If a woman has a mutated BRAC1 gene and uses products containing BPS, her risk for developing breast cancer may increase further,” said principal investigator, Sumi Dinda, Associate Professor at Oakland University in Michigan.

“Despite hopes for a safer alternative to BPA, studies have shown BPS to exhibit similar estrogen-mimicking behaviour to BPA,” Dinda added.

Cancer
Representational image. Pixabay

The results were presented at ENDO 2017, the Endocrine Society’s 99th annual meeting in Orlando.

For the study, the team used two commercially available breast cancer cell lines obtained from women with estrogen-receptor-positive breast cancer, to expose the cancer cells to varying strengths of BPS or to an inactive substance as a control.

Also Read: Blocking Digestive Hormone May Prevent Pancreatic Cancer

Compared with the control, BPS heightened the protein expression in estrogen receptor and BRCA1 after 24 hours, as did estrogen.

After a six-day treatment with BPS, the breast cancer cells in both cell lines reportedly increased in number by 12 per cent at the lowest dose (4 micromolars) and by 60 per cent at eight micromolars. (Bollywood Country)

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UP Govt Imposes Ban on Polythene and Thermocol

Under the new rule, people found with 100 grams of polythene would be fined Rs 1,000 and those with five kilogram will have to cough up Rs 25,000.

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A man collects plastic and other recyclable material from the shores.(VOA)

The Uttar Pradesh government on Wednesday imposed a blanket ban on the manufacture, stocking, sale and transport of all plastic/polythene and thermocol items, an official said.

The ban on disposable cups, plates, spoons, forks and glasses was rolled out on the 72nd Independence Day.

Chief Minister Yogi Adityanath had ordered the ban on polythene bags of less than 50 microns on July 15.

The state will roll out the third and final phase on the Gandhi Jayanti day on October 2 by imposing a total ban on non-bio-degradable polythene.

Packs of flattened polyethylene terephthalate (or PET) bottles are carried into a depot before being pulverized as part of a recycling process at Tokyo PET Bottle Recycle Co. in Tokyo, Aug. 13, 2002. Researchers in Britain and the United States have engineered an enzyme that breaks down such plastics.
Packs of flattened polyethylene terephthalate (or PET) bottles are carried.VOA

Principal Secretary (Urban Development) Manoj Kumar Singh said the government has directed all municipal corporations, district officials and concerned departments to enforce the ban.

There will be special inspections to ensure compliance.

For the first time, the polythene ban has been effective on ground as the government empowered various departments to seize and penalise offenders, rather than leaving it to municipal corporations.

Also Read: Facial Scrub May Contain Millions of Plastic Particles

Under the new rule, people found with 100 grams of polythene would be fined Rs 1,000 and those with five kilogram will have to cough up Rs 25,000. (IANS)