Wednesday September 18, 2019

Compound Found in Grape Skin Can Protect Against Lung Cancer: Research

The resveratrol concentration obtained in the lungs after nasal administration of the formulation was 22 times higher than when taken orally

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grapes, improvement of teeth
Consumption of grapes can lead to having healthier teeth. Pixabay

Researchers have found that a molecule — resveratrol — found in grape skin, seeds and red wine can protect against lung cancer.

Lung cancer is the deadliest form of the disease in the world and 80 per cent of deaths are related to smoking. In addition to tobacco control, effective chemo-prevention strategies are therefore needed.

In experiments in mice, the researchers from the University of Geneva (UNIGE) prevented lung cancer induced by a carcinogen found in cigarette smoke by using resveratrol.

Lung cancer
This formulation is applicable to humans, the researchers noted.

“We observed a 45 per cent decrease in tumour load per mouse in the treated mice. They developed fewer tumours and of smaller size than untreated mice,” said Muriel Cuendet, associate professor at the varsity.

The team conducted their 26-week study on four groups of mice. The first one — the control — received neither carcinogen nor resveratrol treatment. The second received only the carcinogen. The third received both the carcinogen and the treatment, whereas the fourth received only the treatment.

When comparing the two groups that were not exposed to carcinogen, 63 per cent of the mice treated did not develop cancer, compared to only 12.5 per cent of the untreated mice.

“Resveratrol could, therefore, play a preventive role against lung cancer,” Cuendet added.

This formulation is applicable to humans, the researchers noted.

Lung cancer
Tobacco use is one of the main risk factors for a number of chronic diseases, including cancer, lung diseases and cardiovascular diseases, Pixabay

However, when ingested, resveratrol did not prevent lung cancer as it is metabolised and eliminated within minutes. It does not have time to reach the lungs.

Also Read: Wine Tied to Healthier Arteries for Some Diabetics

Conversely, when the molecule was administered through the nasal route, it as found to be much effective and allows the compound to reach the lungs.

The resveratrol concentration obtained in the lungs after nasal administration of the formulation was 22 times higher than when taken orally, the researchers said. (IANS)

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US Health Secretary Applauds Uganda’s Efforts to Control Spread of Ebola in East and Central Africa

Since June, Uganda has identified and isolated four Ebola victims who entered the country from the Democratic Republic of Congo

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US, Health, Uganda
FILE - Health and Human Services Secretary Alex Azar speaks with reporters after a meeting about vaping with President Donald Trump in the Oval Office of the White House in Washington, Sept. 11, 2019. VOA

U.S. Secretary for Health and Human Services Alex Azar has applauded Uganda’s efforts to control the spread of Ebola in east and central Africa; however, while the U.S. remains the primary funder of Uganda’s health care sector, the secretary did not shy away from asking the East African country to find funds to independently sustain its health care budget. US.

Since June, Uganda has identified and isolated four Ebola victims who entered the country from the Democratic Republic of Congo.

The monitoring has prevented the Ebola epidemic which has killed nearly 2,000 people in eastern Congo from crossing the border.

Secretary Azar is leading a U.S. delegation to Rwanda, the DRC and now Uganda regarding Ebola.

US, Health, Uganda
Relatives of the 5-year-old boy who became Ebola’s first cross-border victim, and others, listen as village leaders and health workers educate them about Ebola, in Kirembo, Uganda, June 15, 2019. VOA

“There’s immense work that has had to be done in bolstering preparedness and response capacities. Screening those crossing the borders and responding to the discovery of cases. Uganda, particularly the Ministry of Health and Minister Aceng have risen to the occasion providing a model for the region,” said Azar.

The U.S. is a major financier of Uganda’s health sector, helping to combat AIDS, tuberculosis, malaria, Ebola and improve maternal and child health care.

In fiscal year 2018, the U.S. provided more than $511 million in health care funding.

Secretary Azar encouraged Uganda to be more self-sustaining.

Also Read- US’s Worst Measles Epidemic in 27 Years to be in Its Final Stages as No New Cases Reported

“And we have seen tremendous achievement in Uganda in terms of the building up of the public health system and health care infrastructure as a result of that partnership,” Azar said. “Now of course, overtime that needs to be more self-sustained. And that does require that Uganda invest its own resources also in the health care system.”

Ambassador Deborah Malac expressed confidence Uganda is capable of meeting its own health care needs.

“But one cannot expect that the U.S. government will be the donor of choice in this area, you know, in an open-ended future,” said Malac. “So, it really is about building its capacity and ultimately putting ourselves out of the assistance business.”

On Sunday, there were reports from Tanzania that a doctor who was studying in Uganda had died of a viral infection akin to Ebola. The Tanzanian ministry quickly came out and denied the allegations, calling them rumors.

US, Health, Uganda
U.S. Secretary for Health and Human Services Alex Azar has applauded Uganda’s efforts to control the spread of Ebola in east and central Africa. Pixabay

Yonas Tegegn Woldemariam, the World Health Organization representative in Uganda, expressed concern about the situation.

“This mysterious disease has to be investigated and samples have to be tested. We couldn’t rule out any of the viral hemorrhagic fevers and the investigations will continue,” Yonas said. “And we look forward of the Tanzanian government collaborating as per the International health regulations to address this issue.”

Also Read- Zomato Gold is Still Proving to be a Bone of Contention, Says NRAI Executive

Countries near Congo continue to be on high alert for any new cases of Ebola, with strict adherence to control guidelines set by the WHO. (VOA)