Monday August 26, 2019

Compound Present in Red Wine can Treat Depression and Anxiety

"Resveratrol may be an effective alternative to drugs for treating patients suffering from depression and anxiety disorders," said Ying Xu

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Red Wine, Depression, Anxiety
The plant compound resveratrol displays anti-stress effects by blocking the expression of an enzyme which controls stress in the brain. Pixabay

In a good news for wine lovers, researchers have found a compound present in red wine which can treat depression and anxiety.

The plant compound resveratrol displays anti-stress effects by blocking the expression of an enzyme which controls stress in the brain.

“Resveratrol may be an effective alternative to drugs for treating patients suffering from depression and anxiety disorders,” said Ying Xu, Associate Professor, University at Buffalo in the US.

The findings, published in the journal Neuropharmacolog, shed light onto how neurological processes are impacted by resveratrol — a compound having numerous health benefits and found in the skin and seeds of grapes and berries.

Red Wine, Depression, Anxiety
In a good news for wine lovers, researchers have found a compound present in red wine which can treat depression and anxiety. Pixabay

While research has identified resveratrol to have antidepressant effects, the compound’s relationship to phosphodiesterase 4 (PDE4), an enzyme influenced by the stress hormone corticosterone, was unknown.

Corticosterone regulates the body’s response to stress. Too much stress, however, can lead to excessive amounts of the hormone circulating in the brain and, ultimately, to depression or other mental disorders.

The research also reveals that PDE4, induced by excessive amounts of corticosterone, causes depression- and anxiety-like behaviour.

The enzyme lowers cyclic adenosine monophosphate — a messenger molecule that signals physiological changes such as cell division, change, migration and death — in the body, leading to physical alterations in the brain.

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Resveratrol displayed neuroprotective effects against corticosterone by inhibiting the expression of PDE4. The research lays the groundwork for the use of the compound in novel antidepressants.

According to the researchers, although red wine contains resveratrol, consumption of alcohol has various health risks, including addiction. (IANS)

Next Story

Stress, Anxiety May Not be as Harmful as You Think: Study

According to the researchers, stress causes harm when it exceeds any level that a person can reasonably absorb or use to build psychological strength, likewise, anxiety becomes unhealthy when its alarm makes no sense

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People generally think of stress and anxiety as negative concepts, now new study shows that they often play a helpful, not harmful, role in our daily lives.

“Many Americans now feel stressed about being stressed and anxious about being anxious. Unfortunately, by the time someone reaches out to a professional for help, stress and anxiety have already built to unhealthy levels,” said study researcher Lisa Damour, private-practice psychologist from the US.

Stress usually occurs when people operate at the edge of their abilities — when they push themselves or are forced by circumstances to stretch beyond their familiar zones.

It’s also important to understand that stress can result from both bad and good events. For instance, being fired is stressful but so is bringing a baby home for the first time.

Anxiety, too, gets an unnecessarily bad rap, said the study.

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Today, one in three teens between the ages of 13 and 18 has an anxiety disorder. Pixabay

“As all psychologists know, anxiety is an internal alarm system, likely handed down by evolution, that alerts us to threats both external — such as a driver swerving in a nearby lane — and internal — such as when we have procrastinated too long and it’s time to get started on our work,” Damour said.

“Similarly, if a client shares that she’s worried about an upcoming test for which she has yet to study, I am quick to reassure her that she is having the right reaction and that she will feel better as soon as she hits the books,” she added.

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According to the researchers, stress causes harm when it exceeds any level that a person can reasonably absorb or use to build psychological strength, likewise, anxiety becomes unhealthy when its alarm makes no sense.

“Untreated stress and anxiety can cause persistent misery but can also contribute to a host of additional psychological and medical symptoms, such as depression or an increased risk of cardiovascular disease”, Damour added. (IANS)