Friday September 21, 2018

Consuming 4 Cups of Coffee Daily May Help Boost Heart Functions in Elderly

The team found that caffeine was protective against heart damage in pre-diabetic, obese mice, and in aged mice

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Consuming 4 Cups of Coffee Daily May Help Boost Heart Functions in Elderly as well. Pixabay
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Drinking four cups of coffee daily might be a healthy addiction, especially in older adults, as it can enhance the function of heart cells as well as help recover from heart attacks, say researchers.

The study, conducted on mice showed that coffee promotes movement of a regulatory protein into mitochondria — cell powerhouse — which then enhances their function to protect cardiovascular cells from damage.

The protein called p27, an inhibitor of the cell cycle, was present in mitochondria in the major cell types of the heart.

In these cells, mitochondrial p27 promoted migration of endothelial cells, protected heart muscle cells from cell death and triggered the conversion of fibroblasts into cells containing contractile fibres — all crucial for repair of heart muscle after myocardial infarction or heart attack, and did so at a concentration that is reached in humans by drinking four cups of coffee, the researchers said.

Representational image.
Representational image. Pixabay

“Our results indicate a new mode of action for caffeine, one that promotes protection and repair of heart muscle through the action of mitochondrial p27,” said Judith Haendeler from Heinrich-Heine-University’s Medical Faculty in Germany.

“…enhancing mitochondrial p27 could serve as a potential therapeutic strategy not only in cardiovascular diseases but also in improving health span,” she added.

Also Read: Californian Court Warns “Coffee causes Cancer!”

In the study, published in the journal PLOS Biology, the team found that caffeine was protective against heart damage in pre-diabetic, obese mice, and in aged mice.

“These results should lead to better strategies for protecting heart muscle from damage, including consideration of coffee consumption or caffeine as an additional dietary factor in the elderly population,” Haendeler said. (IANS)

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Coffee Can Reduce Fatality Rate For People Suffering From Chronic Kidney Disease

For the study, described in the journal Nephrology Dialysis Transplantation, the team involved data from 4,863 people.

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Coffee beans, chronic kidney disease
Coffee may prolong lifespan for people with kidney disease. VOA

Drinking coffee may help reduce the risk of death for people with chronic kidney disease, suggests a study.

Comparing with people that consumed less caffeine, patients that consumed higher levels of caffeine presented a nearly 25% reduction in the risk of death over a median follow-up of 60 months.

The possible protective effect of caffeine might be related with effects at vascular level as caffeine is known to promote the release of substances, such as nitric oxide, that improve the function of the vessel, the researchers said.

chronic kidney disease
Kidney disease. IANS

“Our study showed a protective effect of caffeine consumption among patients with chronic kidney disease. The reduction in mortality was present even after considering other important factors such as age, gender, race, smoking, other diseases, and diet,” said lead author Miguel Bigotte Vieira from the Centro Hospitalar Lisboa Norte in Portugal.

“These results suggest that advising patients with kidney disease to drink more caffeine may reduce their mortality. This would represent a simple, clinically beneficial, and inexpensive option,” Vieira added.

For the study, described in the journal Nephrology Dialysis Transplantation, the team involved data from 4,863 people.

Also Read: Smelling Coffee May Boost Your Analytical Skills

However, the researchers emphasised that this observational study cannot prove that caffeine reduces the risk of death in patients with chronic kidney disease, but only suggests the possibility of such a protective effect. (IANS)