Thursday, December 3, 2020
Home Lead Story Covid-19 Infected Patients' Blood Can Tell Severity Of Illness

Covid-19 Infected Patients’ Blood Can Tell Severity Of Illness

Cytokines - proteins produced by immune cells - are responsible for severe overreactions

Clinicians can examine Covid-19 patients’ blood to identify those at greatest risk of severe illness and to pinpoint those most likely to need a ventilator, according to a new study.

The discovery could lead to new treatments to prevent deadly “cytokine storms” seen in severe cases of Covid-19. It also may help explain why diabetes contributes to worse outcomes in patients with the coronavirus.

Follow us on Twitter to get more exciting updates from us!!

The researchers from the University of Virginias (UVA) found that the levels of a particular cytokine in the blood upon diagnosis could be used to predict later outcomes.

Cytokines – proteins produced by immune cells – are responsible for severe overreactions by the immune system, known as cytokine storms, associated with Covid-19 and other serious illnesses.

“The immune response that we discovered to predict severe shortness of breath in Covid-19 is known in other pulmonary diseases to cause damage,” said study researcher Bill Petri from the UVA.

“So this could lead to a novel way to prevent respiratory failure in individuals infected with the new coronavirus, by inhibiting this immune cytokine. We plan to test this in a model of Covid-19 prior to considering a clinical trial,” Petri added.

For the findings, the research team identified 57 Covid-19 patients treated at UVA who ultimately required a ventilator.

They then tested blood samples taken from the patients within 48 hours of diagnosis or hospital admission.

The research team compared the results with those from patients who did not wind up needing a ventilator.

Covid-19 patients can be identified by their blood reports
The researchers from the University of Virginias (UVA) found that the levels of a particular cytokine in the blood upon diagnosis could be used to predict later outcomes. Pixabay

Cytokine storms, in which the immune system spirals out of control, are typically associated with an established group of cytokines.

But the best predictor of Covid-19 outcomes was an “underappreciated” cytokine more associated with allergies, the researchers reported.

High levels of that cytokine, IL-13, were associated with worsened Covid-19 outcomes regardless of patients’ gender, age, or other health problems.

The researchers also identified two more cytokines associated with severe outcomes, though the duo had less ability to predict the need for a ventilator.

Covid-19 patients can be identified by their blood reports
This “pro-inflammatory response,” they said, may help explain why diabetes is associated with worse Covid-19 outcomes. Pixabay

In addition, the researchers found that levels of two other cytokines were significantly higher in patients with elevated blood sugar.

Also Read: Covid-19 Can Infect Brain Cells, Says Research

This “pro-inflammatory response,” they said, may help explain why diabetes is associated with worse Covid-19 outcomes. In short, the body is primed to respond too strongly to the infection.

The researchers said the discovery could become part of a scoring system to let doctors flag at-risk COVID-19 patients for closer monitoring and personalized interventions.

The finding also identifies cytokines doctors could target as a new treatment approach. (IANS)

STAY CONNECTED

19,120FansLike
362FollowersFollow
1,778FollowersFollow

Most Popular

World Needs To Decrease Fossil Fuels Production By 6%

Even though countries plan to increase their fossil fuel production over the next decade, research shows that the world needs to decrease the production...

The Oscar Awards Gala Will Not Go Virtual, In-Person Telecast Will Happen

There were a lot of speculations around how the Oscars would be held amid the Covid pandemic, and it is now confirmed the award...

India Is A Key Market For The Japanese Entertainment Industry

Indian interest towards Japanese culture has been growing significantly over the last few years, especially amongst Gen Z, believes Kaoru Miyamoto, Director General, Japan...

Tips To Follow While Protecting Your Kids From Potential Health Effects

Children are more sensitive to the effects of smog and air pollution than adults. Here are some practical tips for you to follow to...

AWS Is A Game Changer For Artists On Netflix

As video streaming turns out to be the savior for millions of people working from homes to refresh their minds, Amazon Web Services (AWS)...

Twitch And Beauty: Could The Streaming Site Rival Instagram’s Hold On The Influencer Market

By Harry Green The key to influencing is access to the audience. Instagram is flexible, in this regard: posts, stories, and live streams are integral...

Is The Previous Generation iPhone Best For You

By Zedd Salem Apple’s iPhones are undoubtedly some of the best smartphones out there. From responsive performance to compelling hardware designs, you can never go...

3 Real Estate Investment Types You Can’t Overlook in 2021

By Sana Faisal Real estate is an incredibly profitable investment. Understanding the difference between residential, commercial, and raw land real estate is essential to selecting...

Recent Comments