Thursday February 22, 2018

Cure of Diabetes may be just a few years away

0
//
489
Republish
Reprint

Feb. 11, 2016: This video produced by Voice of America and brought to you by NewsGram highlights 2 things:
1. Insulin Pumps currently are automated, ie, you have to keep monitoring glucose levels and then decide the insulin dose to be given via Insulin pumps. The scientists say, in next 5 years, automated insulin pumps would become a reality.
2. Ongoing experiments in mice give hope that even the cure of diabetes may not be far away.

Scientists at two of the top U.S. universities say they have made significant advances in their quest to find a more efficient treatment for diabetes and eventually a cure. According to the International Diabetes Federation, the disease affects more than 370 million people worldwide. VOA’s George Putic reports.

Excess sugar, or glucose, in your blood is not good.  But a healthy body regulates it through insulin, produced in the organ called the pancreas. If the body fails to do that, either because of genetics, or an unhealthy lifestyle, diabetics have to adopt a grueling routine of constant monitoring of blood sugar and injecting insulin for the rest of their lives.

Both insulin monitors and delivery devices called insulin pumps, are available, but so far, creating an automatic injector that does not require monitoring has proved to be a difficult problem.

After working on it for almost 20 years, scientists at Harvard University say they may be close to solving it.

Frank Doyle of Harvard University says: “In essence, we use a patient model, a computational model, a mathematical model, to forecast into the future. So we get a sense of how past insulin affects future glucose, how the past trajectory of glucose is going to play out for the next hour or two.”

Scientists say automatic insulin pumps should be on the market within five years.

Finding a cure for diabetes would be even better and these mice may  hold the key.

In the type of diabetes caused by genetic disposition, the human immune system kills pancreas cells that produce insulin.  A jello-like substance engineered in the laboratory of the Massachusetts Institute of Technology shields those cells from the attack.

Daniel Anderson of Massachusetts Inst of Technology says: “We can take these human islets from stem cells and actually cure these diabetic mice for months. We have also shown that in primates we can put these little balls of new material in the abdominal space of primates and see that they don’t form scar tissue which is an important step towards thinking of using them in people.”

Scientists are optimistic that one way or another, or maybe with a combination of approaches, they will bring relief to diabetes sufferers within a few years. (GEORGE PUTIC, VOANEWS, WASHINGTON)

Click here for reuse options!
Copyright 2016 NewsGram

Next Story

Common BP Drug May Prevent Onset Of Type 1 Diabetes

For the study, published in the Journal of Clinical Investigation, the team used a supercomputer, on the lab bench, in mice, and in humans

0
//
20
Type 1 Diabetes

A drug commonly used to control high blood pressure may be also effective in preventing the onset of Type 1 diabetes in up to 60 percent of those at risk, researchers say.

The drug, methyldopa, has been used for over 50 years to treat high blood pressure in pregnant women and children and is also on the World Health Organization’s list of essential drugs.

Methyldopa was found to block a molecule called DQ8 — found in some 60 percent at the risk of getting Type 1 diabetes — which significantly increases the chance of getting the disease.

Blocking specifically the DQ8 molecule could also block the onset of the disease, the study found.

 

ALSO READ: Eat According to Your Blood Type and See the Benefits Yourself!

“This is the first personalized treatment for Type 1 diabetes prevention,” said Aaron Michels, Associate Professor of medicine at University of Colorado – Anschutz.

“With this drug, we can potentially prevent up to 60 percent of Type 1 diabetes in those at the risk for the disease. This is very significant development,” Michels added.

Type 1 Diabetes

For the study, published in the Journal of Clinical Investigation, the team used a supercomputer, on the lab bench, in mice, and in humans.

They found that methyldopa not only blocked DQ8, but it did not also harm the immune function of other cells like many immunosuppressant drugs do.

ALSO READ: Diabetes can hamper your reproductive health

“We can now predict with almost 100 percent accuracy who is likely to get Type 1 diabetes. The goal, with this drug, is to delay or prevent the onset of the disease among those at risk,” Michels said.

The drug is taken orally, three times a day.

Besides, diabetes, the same approach of blocking specific molecules can be used in other autoimmune diseases such as rheumatoid arthritis, coeliac disease, multiple sclerosis, systemic lupus erythematosus and others, the researchers noted. (IANS)

Next Story

Night Shifts May Raise Risk Of Diabetes

For the study, published in the journal Diabetes Care, the team examined data from more than 270,000 people, including 70,000 who provided in-depth lifetime employment information and a sub-group of more than 44,000 for whom genetic data were available