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Daily Exercise Can Help People With Heart Disease

When heart disease runs in the family, more physical activity may be the best defence, say researchers.

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Exercise, representational image . IANS
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When heart disease runs in the family, more physical activity may be the best defence, say researchers. According to the findings reported in the American Heart Association’s journal Circulation, greater grip strength, more physical activity and better cardiorespiratory fitness are associated with reduced risk for heart attacks and stroke — even among people with a genetic pre-disposition for heart disease.

Gastroesophageal Reflux Disease is simply known as heartburn. Wikimedia Commons
Heart disease can run in families as well. Wikimedia Commons

“The main message is that being physically active is associated with a lower risk of heart disease, even if you have a high genetic risk,” said Erik Ingelsson, lead study author and Professor of Medicine at Stanford University’s School of Medicine in California. To reach this conclusion, researchers looked at data from roughly a half-million people in the UK Biobank database.

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For participants with an intermediate genetic risk for cardiovascular diseases, those with the strongest grips were 36 per cent less likely to develop coronary heart disease and had a 46 per cent reduction in their risk for atrial fibrillation, compared to study participants with the same genetic risk who had the weakest grips.

Among individuals deemed at high genetic risk for cardiovascular diseases, high levels of cardiorespiratory fitness were associated with a 49 per cent lower risk for coronary heart disease and a 60 per cent lower risk for atrial fibrillation compared to study participants with low cardiorespiratory fitness.

Heart Disease can be minimised by exercise.

“The study is not a prescription for a specific type or amount of exercise and because the results come from an observational study, Ingelsson said, adding that “we can’t definitely claim a causal connection.” Nonetheless, the researchers said the data is robust and the results are worthy for consideration in guidelines. IANS

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Learn How Muscles Help Burn Fat During Exercise

Burning fat is likely to impact multiple aspects of metabolic health related to diabetes, heart disease and other conditions

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Further research revealed that BAIBA levels rise during exercise and are inversely associated with metabolic risk factors. Pixabay

Ever thought what helps burn fat across your body while exercising? According to a study, it is a molecule in our muscles that is produced during exercise and contributes to the beneficial effects of exercise on metabolism.

“Our finding bolsters the underlying notion that signals generated in exercising muscle are released into the circulation and influence other tissues such as fat cells and liver,” said senior author Robert Gerszten at Massachusetts General Hospital, the primary teaching hospital of Harvard Medical School.

The researchers knew that a protein called PGC-1? regulates metabolic genes in muscle and contributes to the response of muscle to exercise.

But how this protein conveys signals to other tissues was unclear so far.

Gerszten and his colleagues forced the expression of PGC-1? in muscle cells and then looked for metabolites that were secreted from the cells.

Exercise
BAIBA also decreased weight gain and helped balance blood sugar levels in mice, said the study published in the journal Cell Metabolism. Pixabay

They identified ?-aminoisobutyric acid (BAIBA) as one such metabolite and found that it increased fat cells’ expression of genes that are involved with burning calories.

BAIBA also decreased weight gain and helped balance blood sugar levels in mice, said the study published in the journal Cell Metabolism.

Further research revealed that BAIBA levels rise during exercise and are inversely associated with metabolic risk factors.

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“The findings suggest that BAIBA may contribute to exercise-induced protection from metabolic diseases. Manipulating BAIBA – or enzymes that generate BAIBA – may have therapeutic potential,” said Gerszten.

Burning fat is likely to impact multiple aspects of metabolic health related to diabetes, heart disease and other conditions, the study concluded.  (IANS)

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