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Recreational drug Ketamine is likely to have fast-acting benefits in treating symptoms of depression as well as reducing suicidal thoughts, say researchers, including one of an Indian-origin.
The findings of the trial, published in the American Journal of Psychiatry, showed use of Ketamine, also licensed as an anaesthetic, through a nasal spray, led to significant improvements in depressive symptoms and reduction in suicidal thoughts in the first 24 hours.
Esketamine could be an important treatment to bridge the gap as it can help in the rapid treatment compared to the delayed effects of most common antidepressants, which take four to six weeks to become fully effective, said Jaskaran B. Singh, from the Janssen Research & Development in San Diego, US.
The results support nasal spray esketamine as a possible effective rapid treatment for depressive symptoms in patients assessed to be at imminent risk for suicide, the researchers noted.
For the study, a small group of participants randomly assigned to one of two groups – either receiving esketamine or placebo twice a week for four weeks, and found a significant improvement in depression scores and decreased suicidal ideation in the esketamine group compared to the placebo group at four hours and at 24 hours.
However, at 25 days, the effects had levelled out.
While there esketamine dependence or misuse was not observed in the trial, the researchers suggested for effective controls on the distribution and use of ketamine.
They argued that steps to control the use of ketamine would not be aimed at preventing its use for beneficial purposes but would allow for treatment to “continue to be available to those with need, while the population that is at-risk for abuse is protected from an epidemic of misuse.” IANS
Groove to the latest wedding song, Say Yes To The Dress India, with the king of Music, Badshah, who for the first time, will be donning five never seen before avatars including that of an event manager, pandit, chef, rapper and a fashion designer in the music video displaying an Indian wedding. The song will be available on all leading audio streaming services.
Joining him as the female lead singer is Payal Dev and the track is composed by Aditya Dev, produced by The Content Team. Highly celebrated Punit J Pathak has choreographed it. The video showcase real-time brides but also successfully brings out the show's core theme of fun, celebration and giving each bride the attention they deserve. While the show is visually mesmerizing, the rapper's newest wedding track is sure to get one swaying, making its way to the top of your playlist!
It's always a fun time working with Badshah and this song is nothing less than magic to the ears. Since we thoroughly enjoy this track ourselves, I am sure the audiences too will give it just the amount of love it deserves", said Singer Payal Dev. Neeraj Sharma, Founder and Principal producer of The Content Team said, "We at 'TCT' believe in coming up with creative solutions that bring audiences closer to the content. Buoyed by the recent successes of some of the prestigious singing reality shows in India, we have a fair understanding of what consumers are looking forward to in the music industry. We are thrilled to bring to you the biggest shaadi blockbuster of the year." (IANS/ MBI)
(Keywords: Punit J Pathak, Aditya Dev, Payal Dev, Badshah, king of Music, Yes To The Dress India, wedding song)
Rapper Cardi B has been named Playboy's first-ever creative director in residence. The 'WAP' hitmaker took to social media to share the news, which will see her become the very first person to be creative director in residence of the iconic brand, reports femalefirst.co.uk. Sharing the news on Instagram, she said: "Introducing the FIRST EVER Creative Director In Residence at the legendary @playboy, it's ME!!! Joining the @playboy family is a dream and I know y'all are going to love what we put together. "I'm startin this party right as the Founding Creative Director and a founding member of Centerfold the new creator-led platform from Playboy coming soon!! We're going to have soooooo much fun."
According to a press release obtained by People magazine, Cardi's role will involve providing "artistic direction" across the Playboy brand. | IANS
According to a press release obtained by People magazine, Cardi's role will involve providing "artistic direction" across the Playboy brand. The release stated: "Cardi will provide artistic direction across co-branded fashion and sexual wellness merchandise collections, digital editorial, experiential activations and more. "In addition, Cardi B will serve as the Founding Creative Director and a founding member of Playboy's upcoming creator-led platform, Centerfold."
According to People, Centerfold is expected to launch this month and will be Playboy's social content platform that will offer creators tools to directly interact with fans. In the release, 29-year-old Cardi said: "It is a dream come true to officially join the Playboy family. I can't believe this is real. For as long as I can remember, I've felt connected to Playboy. It's truly the original platform for uncensored creativity and I'm inspired by its incredible legacy of fighting for personal freedoms. I have so many ideas already - I can't wait! "I'm also excited to launch our new creator-led platform, Centerfold. Creators today deserve to express themselves freely and unfiltered. They deserve to feel safe in their creativity and sexuality. And they deserve to own their future. "This is what Centerfold is all about. For all those creators out there doing bold, revolutionary, truly culture-shifting things, come join me." (IANS/ MBI)
(Keywords: Instagram, WAP, residence, creative director, Playboy, Cardi B, Rapper)
As the Omicron variant threat looms, Google is reconsidering its plans to ask full-time employees to return to offices by January 10. According to an email from Google VP Chris Rackow, seen by CNBC, Google will not be requiring its employees to return to offices on January 10 as expected after all. The company has changed its return to work plans several times as the pandemic evolved.
In August, when the delta variant was a top concern, Google had announced plans for hybrid return-to-work till January 10, 2022. Rackow said in the email that full-time employees will wait until the new year to assess when US offices can safely return to a "stable, long-term working environment. "None of the US locations will adopt the hybrid working mandate on January 10 as planned," he added. Rackow said that Google will allow specific locations to decide their timelines for returning their respective local workforces to the office.
Apple is reportedly asking employees to return to offices starting February 1 as part of a hybrid work pilot who will be able to work remotely for four weeks a year. After the first US case of the Omicron Covid-19 variant was reported in California, the federal government was set to announce a bunch of measures to help counter the virus, including campaigns to increase vaccinations and booster shots, additional testing requirements for travellers entering the country from abroad and plans to make rapid at-home coronavirus testing free for more people. International travellers coming to the US will have to test within a day of departure, regardless of vaccination status, rather than the 72 hours currently required for vaccinated travellers, under new protocols early next week. The new testing rules will apply both to US citizens and foreign nationals entering the country. (IANS/ MBI)
(Keywords: Office, Google, Omicron variant, apple, january, employees)