Friday November 16, 2018

Study: Depression Can Be Cut by Ketamine

Ketamine, the drug can be helpful to cut off depression and suicidality

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A man in depression. Pixabay
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Recreational drug Ketamine is likely to have fast-acting benefits in treating symptoms of depression as well as reducing suicidal thoughts, say researchers, including one of an Indian-origin.

The findings of the trial, published in the American Journal of Psychiatry, showed use of Ketamine, also licensed as an anaesthetic, through a nasal spray, led to significant improvements in depressive symptoms and reduction in suicidal thoughts in the first 24 hours.

A woman in depression.
A woman suffering from depression.

Esketamine could be an important treatment to bridge the gap as it can help in the rapid treatment compared to the delayed effects of most common antidepressants, which take four to six weeks to become fully effective, said Jaskaran B. Singh, from the Janssen Research & Development in San Diego, US.

The results support nasal spray esketamine as a possible effective rapid treatment for depressive symptoms in patients assessed to be at imminent risk for suicide, the researchers noted.

For the study, a small group of participants randomly assigned to one of two groups – either receiving esketamine or placebo twice a week for four weeks, and found a significant improvement in depression scores and decreased suicidal ideation in the esketamine group compared to the placebo group at four hours and at 24 hours.

Also Read: Depression Can Negatively Impact Heart Patients

However, at 25 days, the effects had levelled out.

While there esketamine dependence or misuse was not observed in the trial, the researchers suggested for effective controls on the distribution and use of ketamine.

They argued that steps to control the use of ketamine would not be aimed at preventing its use for beneficial purposes but would allow for treatment to “continue to be available to those with need, while the population that is at-risk for abuse is protected from an epidemic of misuse.”  IANS

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Loneliness And Depression Can Be Linked to Social Media: Study

It is unclear if the depressing effects of social media will cross generational lines to older or younger people

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Social Media,
This photo taken March 22, 2018, shows apps for WhatsApp, Facebook, Instagram and other social networks on a smartphone. VOA

University of Pennsylvania researchers say that for the first time they have linked social media use to increases in depression and loneliness.

The idea that social media is anything but social when it comes to mental health has been talked about for years, but not many studies have managed to actually link the two.

To do that, Penn researchers, led by psychologist Melissa Hunt, designed a study that focused on Facebook, Snapchat and Instagram.

The results were published in the November issue of the Journal of Social and Clinical Psychology.

Social media. Offensive Speech
An iPhone with Twitter, Facebook and other apps, May 21, 2013. U.S. internet companies are taking a harder look at their policies that have promoted free expression around the world.. VOA

How study worked

The study was conducted with 143 participants, who before they began, completed a mood survey and sent along photos of their battery screens, showing how often they were using their phones to access social media.

“We set out to do a much more comprehensive, rigorous study that was also more ecologically valid,” Hunt said. That term, ecologically valid, means that the research attempts to mimic real life.

The study divided the participants into two groups: The first group was allowed to maintain their normal social media habits. The other, the control group, was restricted to 10 minutes per day on each of the three platforms: Facebook, Snapchat and Instagram.

The restrictions were put in place for three weeks and then the participants returned and were tested for outcomes such as fear of missing out (FOMO), anxiety, depression and loneliness.

Social Media
Chiara Valenzano, right, photographs her food as she has lunch with her friend Giulia Terranova at the ‘This is not a Sushi bar’ restaurant, in Milan, Italy, Oct. 16, 2018. At the restaurant, payment can be made according to the number of Instagram followers one has. VOA

Results of study

The results showed a very clear link between social media use and increased levels of depression and loneliness.

“Using less social media than you normally would leads to significant decreases in both depression and loneliness,” Hunt said. “These effects are particularly pronounced for folks who were more depressed when they came into the study.”

She calls her findings the “grand irony” of social media.

What is it about social media that’s just so depressing?

Hunt says that it’s two major things. The first is that social media invites what Hunt calls “downward social comparison.” When you’re online, it can sometimes seem that “everyone else is cooler and having more fun and included in more things and you’re left out,” she said. And that’s just generally demoralizing.

Social Media
The study was conducted with 143 participants, who before they began, completed a mood survey Pixabay

The second factor is a bit more nuanced.

“Time is a zero-sum game,” Hunt told VOA. “Every minute you spend online is a minute you are not doing your work or not meeting a friend for dinner or having a deep conversation with your roommate.”

And these real life activities are the ones that can bolster self-esteem and self worth, Hunt said.

What to learn

So what’s the takeaway?

social media
A girl uses her mobile phone in Jakarta, Indonesia, July 5, 2017. A researcher in Britain says her findings suggest young girls who are more active on social media have lower levels of well-being in their teens. VOA

People are on their devices, and that’s not going to change, she said. But as in life, a bit of moderation goes a long way.

“In general, I would say, put your phone down and be with the people in your life,” she added.

Also Read: Childhood Violence May Spur Puberty, Depression: Study

Hunt pointed out a few caveats to the study. First, it was done exclusively with 18- to 22-year-olds, and it is unclear if the depressing effects of social media will cross generational lines to older or younger people, Hunt said. But she expects her results should generalize at least for people through the age of 30.

Hunt says she is now beginning a study to gauge the emotional impact of dating apps. (VOA)