Never miss a story

Get subscribed to our newsletter


×
Doctors can use direct whole genome sequencing to get information on drug resistance mutations in TB. Pixabay

Genetic diagnostic and drug discovery research firm MedGeneome Labs on Thursday claimed to have developed the first whole genomic sequencing-based test to detect drug-resistant mutation in tuberculosis (TB) bacteria.

“The breakthrough DNA test will enable a doctor to correctly prescribe the most effective drug to a TB patient without a time-consuming trial and error process,” said the city-based clinical data-driven Labs.


Announcing its foray into infectious disease testing in TB, central nervous system (CNS), systemic and eye infections, the company said India had the largest number of multi-drug resistant (MDR) TB cases.


A breakthrough DNA test will enable doctors to correctly prescribe the most effective medicine to a TB patient. Pixabay

“India has the largest number of MDR-TB cases. Our spit sequence can be a boon for TB patients, clinicians and healthcare agencies to achieve the sustainable development goal of eliminating TB by 2025,” Labs Chief Operating Officer V.L. Ramprasad told reporters here.

“The test is based on the whole-genome sequencing of mycobacterium tuberculosis (MTB), the TB causing bacteria, to assess the mutations in bacteria’s genome and allows a clinician to determine which drug will work for a patient,” he said.

Mumbai-based P.D. Hinduja Hospital and Medical Research Centre head Camilla Rodrigues said the test was validated with 100 samples recording 100 per cent sensitivity and 98.04 per cent specificity compared with line probe assay technology.


India had the largest number of multi-drug resistant (MDR) TB cases. Pixabay

“Of the 100 samples, 50 were tested in our hospital. The findings in the manuscript are under review for publication,” Rodrigues said on the occasion.

Noting that the process of analyzing the drug resistance was long, which is delaying early treatment for MDR-TB patient, Rodrigues said the current expertise allowed testing resistance only on 4 drugs, which makes the patient wait until testing on all possible drugs concluded.

Also Read: The Health Benefits of Testing Your Cortisol Levels

“Direct whole genome sequencing reveals information on drug resistance mutations for all anti-TB drugs in 10 days. Our testing will help to optimise the management of an MDR-TB patient”, she added. (IANS)


Popular

Photo by febri sym on Unsplash

Achieving soft, beautiful and happy skin is a dream for most of us or at least a long-pending item on our wish list.

Achieving soft, beautiful and happy skin is a dream for most of us or at least a long-pending item on our wish list. While there are lot of suggestions, a laundry list of do's and don'ts to follow, there are some basics that don't change. We have to understand that happy skin is a holistic process that requires one to work on building healthy habits combined with good skincare.

Here's a ready reckoner by ITC Fiama of tried and tested skincare habits that will serve as a reminder that skincare doesn't need to be complicated, it just needs to be consistent.


* Cleanse & Moisturise -- The first and the simplest step towards healthy skin is regular cleansing and moisturising, it is advisable to use a moisturizing body soap that ensures your skin gets the right nutrients and remains supple and nourished. A great product suited to this requirement is Fiama Gel Bathing Bar, which is enriched with nature's goodness. Fiama's bathing bars come in 5 variants and they help moisturize the skin making it appear soft, happy and bouncy.

Keep Reading Show less
Photo by Pixabay

It is true that street performances has been existing in India since ancient times. But, it was Philip Astley who brought the concept of circus in India in the 1880s. Interestingly, Astley is known as the father of modern circus.

Birth of the Great Indian Circus

Keep Reading Show less
Unsplash

API security testing is a process that checks API functions for security vulnerabilities.

By- Naman Rastogi

The first thing to understand about API security testing is that it is not a one-size-fits-all process. Testers must take into account the scope of the project, as well as the specific needs of developers and end-users. This article will provide you with some basic guidelines for an API security testing program. It will also outline some API security tests that you should consider including in your API testing process.

Keep reading... Show less