Saturday September 21, 2019

MinION, device to cure urinary tract infection

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New York: Urinary tract infections could be treated more quickly and efficiently now, using a DNA sequencing device which is similar to the size of a USB stick, says a study.

“We found that this device, which is the size of a USB stick, could detect the bacteria in heavily infected urine – and provide its DNA sequence in just 12 hours. This is a quarter of the time needed for conventional microbiology,” said one of the researchers Justin O’Grady from University of East Anglia in England.

The new device called MinION detected bacteria from urine samples four times more quickly than traditional methods of culturing bacteria.

The new method can also detect antibiotic resistance – allowing patients to be treated more effectively, the researchers said.

“Swift results like these will make it possible to refine a patient’s treatment much earlier – and that is good for the patient, who gets the ‘right’ antibiotic,” O’Grady said.

“This technology is rapid and capable not only of identifying the bacteria in UTIs (urinary tract infections), but also detecting drug-resistance at the point of clinical need,” O’Grady noted.

Professor David Livermore from University of East Anglia’s Norwich Medical School explained that urinary tract infections are among the most common reasons for prescribing antibiotics.

“Antibiotics are vital, especially if bacteria has entered the bloodstream, and must be given urgently. But unfortunately it takes two days to grow the bacteria in the lab and test which antibiotics kill them,” Livermore noted.

As a result, doctors must prescribe a broad range antibiotics, targeting the bacteria most likely to be responsible, and then adjust treatment once the lab results come through, he pointed out.

“This ‘carpet-bombing’ approach represents poor antibiotic stewardship, and it is vital that we move beyond it. The way to do so lies in accelerating laboratory investigation, so that treatment can be refined earlier, benefitting the patient, who gets an effective antibiotic, and society, whose diminishing stock of antibiotics is better managed,” Livermore said.

The findings were presented at an international medical conference run jointly by the American Society for Microbiology’s Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC) and the International Society of Chemotherapy (ICC) at San Diego in the US.

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Salmonella Bacteria Found In MDH ‘Sambhar Masala’ In US

After the US Food and Drug Administration (FDA) detected the salmonella bacteria in the MDH brand 'sambar masala'

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salmonella, bacteria, MDH, masala, US, India
Dosa with Sambhar and other side dishes. Wikimedia Commons

After the US Food and Drug Administration (FDA) detected the salmonella bacteria in the MDH brand ‘sambar masala’, the company is withdrawing at least three lots of the product from the shelves.

Produced by R Pure Agro Specialities and distributed by the House Of Spices (India), the product was tested by the FDA through a certified laboratory and found positive for salmonella.

The recalled MDH sambar masala was distributed in northern California retail stores, House Of Spices (India) said in a statement.

salmonella, bacteria, MDH, masala, US, India
Salmonella bacteria found in MDH ‘Sambhar Masala’ sold in US. Wikimedia Commons

Consumption of food contaminated with salmonella can cause salmonellosis, one of the most common bacterial foodborne illnesses.

The most common symptoms of salmonellosis are diarrohea, abdominal cramps, and fever within 12 to 72 hours after eating the contaminated product.

The illness usually lasts four to seven days. Most people recover without treatment. In some persons, however, the diarrohea may be so severe that the patient requires hospitalisation.

ALSO READ: Nano and Microplastics Harming Drinking Water for Humans, Says Study

Older adults, infants, and persons with weakened immune systems are more likely to develop severe symptoms.

The recall was initiated after it the FDA discovered that the salmonella contaminated products were distributed.

“Consumers who have purchased the MDH SAMBAR MASALA, 3.5 oz (100g) are urged to return them to the place of purchase for a full refund,” House Of Spices said in the statement issued last week. (IANS)