Tuesday November 12, 2019

Children Prone To Disorder With Mothers Having Diabetes During Pregnancy

"This link of diabetes in children and youth with gestational diabetes in the mother has the potential to stimulate clinicians, parents, and children and youth themselves to consider the possibility of diabetes"

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The study showed that a child or teenager whose mother had gestational diabetes -- diabetes during pregnancy -- was nearly twice as likely to develop diabetes before the age of 22 years. Pixabay

Children and youths whose mothers had diabetes during their pregnancy are themselves at an increased risk of the disorder, say researchers, including one of Indian-origin.

The study showed that a child or teenager whose mother had gestational diabetes — diabetes during pregnancy — was nearly twice as likely to develop diabetes before the age of 22 years.

diabetes
According to World Health Organzation, diabetes can be treated and its consequences can be avoided or delayed with diet, physical activity, medication and regular screening and treatment for complications. Pixabay

The association was found in children from birth to the age of 22 years, from birth to 12 years, and from 12 to 22 years, said the study, published in Canadian Medical Association Journal.

“Although Type-1 and Type-2 diabetes in parents are well-established risk factors for diabetes, we show that gestational diabetes mellitus may be a risk indicator for diabetes in the mother’s children before age 22,” said Kaberi Dasgupta, clinician-scientist from the McGill University in Canada.

“This link of diabetes in children and youth with gestational diabetes in the mother has the potential to stimulate clinicians, parents, and children and youth themselves to consider the possibility of diabetes if offspring of a mother with gestational diabetes mellitus develop signs and symptoms such as frequent urination, abnormal thirst, weight loss or fatigue,” said Dasgupta.

diabetes
“Although Type-1 and Type-2 diabetes in parents are well-established risk factors for diabetes, we show that gestational diabetes mellitus may be a risk indicator for diabetes in the mother’s children before age 22,” Pixabay

Also Read: Collective Attention Span Among People Decreases Rapidly as of 24/7 News Availability
According to World Health Organzation, diabetes can be treated and its consequences can be avoided or delayed with diet, physical activity, medication and regular screening and treatment for complications.

For the study, the researchers included 73,180 mothers. (IANS)

Next Story

Impaired Liver Function During Pregnancy Leads To Obese Kids

Impaired liver function during pregnancy increases the risks of obesity in kids

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Impaired liver function during pregnancy may increase the risk of obesity in children. PIxabay

Impaired liver function during pregnancy may alter gut bacteria composition and increase the risk of obesity in children, according to a new study.

In a rodent of model of the most common liver disease in pregnancy, the composition of gut bacteria in offspring was altered and liver function impaired, particularly when they were fed a Western-style, high-fat diet.

“These findings further suggest that health during pregnancy can have long-term effects on children. In this case they suggest that gut microbiome alterations, may increase the risk of obesity in children, when fed a western style, high-fat diet, ” said study researcher Caroline Ovadia from King’s College London.

The most common liver disease in pregnancy, intrahepatic cholestasis (ICP), reduces the release of digestive fluid bile from the liver causing bile acids to build up in the blood, impairing liver function. This causes severe itching in the mother and increases risks of stillbirth and preterm birth for the baby.

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In a rodent of model of the most common liver disease in pregnancy, the composition of gut bacteria in offspring was altered and liver function impaired. Pixabay

Previous studies suggest that children of women with ICP are more likely to develop childhood obesity.

For the findings, the research team investigated how gut microbiota are affected in the offspring of a mouse model of ICP.

The results reported that the offspring had a different gut microbiome composition and liver function, particularly when fed a high-fat diet, which could contribute to impaired metabolism and increase risk of obesity.

The results suggest that mice born to mothers with ICP, or other liver diseases, may benefit from maintaining a healthy diet and should avoid fatty foods.

These findings also suggest that targeting microbiome composition with treatment strategies in pregnant women, such as using pre-biotics or pro-biotics, could help prevent the risk of child obesity.

Also Read- Parents With Only Child More Likely To Tackle Obese Kids

“Understanding changes in composition of the gut microbiome and their effects may provide new ways of diagnosing patients at particular risk of obesity before it occurs. We could then develop personalised medicine and target appropriate treatments to alter gut bacteria accordingly,” Ovadia added.

The study was presented at The Society for Endocrinology Annual Conference in the UK. (IANS)