Saturday January 18, 2020

Diabetes During Pregnancy Spikes up the Risk in Kids Later

For the study, the researchers included 73,180 mothers

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pregnancy
The study showed that a child or teenager whose mother had gestational diabetes -- diabetes during pregnancy -- was nearly twice as likely to develop diabetes before the age of 22 years. Pixabay

Children and youths whose mothers had diabetes during their pregnancy are themselves at an increased risk of the disorder, say researchers, including one of Indian-origin.

The study showed that a child or teenager whose mother had gestational diabetes — diabetes during pregnancy — was nearly twice as likely to develop diabetes before the age of 22 years.

The association was found in children from birth to the age of 22 years, from birth to 12 years, and from 12 to 22 years, said the study, published in Canadian Medical Association Journal.

Diabetes
Representational image. Pixabay

“Although Type-1 and Type-2 diabetes in parents are well-established risk factors for diabetes, we show that gestational diabetes mellitus may be a risk indicator for diabetes in the mother’s children before age 22,” said Kaberi Dasgupta, clinician-scientist from the McGill University in Canada.

“This link of diabetes in children and youth with gestational diabetes in the mother has the potential to stimulate clinicians, parents, and children and youth themselves to consider the possibility of diabetes if offspring of a mother with gestational diabetes mellitus develop signs and symptoms such as frequent urination, abnormal thirst, weight loss or fatigue,” said Dasgupta.

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According to World Health Organzation, diabetes can be treated and its consequences can be avoided or delayed with diet, physical activity, medication and regular screening and treatment for complications.

For the study, the researchers included 73,180 mothers. (IANS)

Next Story

Air Pollution, Stress Associated with Thought Problems in Kids: Researchers

Stress likely leads to wide-ranging changes in, for example, epigenetic expression, cortisol, inflammation, and brain structure and function

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Pollution, pollutants, India, air pollution, WHO, diwali
Delhi air quality continues to be 'very poor'. VOA

Parents, please take note. Researchers have revealed that kids with elevated exposure to early life stress in the home and increased prenatal exposure to air pollution exhibited heightened symptoms of attention and thought problems.

Early life stress is common in youth from disadvantaged backgrounds who also often live in areas with greater exposure to air pollution, according to the study, published in the Journal of Child Psychology and Psychiatry.

“Prenatal exposure to polycyclic aromatic hydrocarbons, a neurotoxicant common in air pollution, seems to magnify or sustain the effects of early life social and economic stress on mental health in children,” said study first author David Pagliaccio from Columbia University in the US.

“Air pollutants are common in our environment, particularly in cities, and given socioeconomic inequities and environmental injustice, children growing up in disadvantaged circumstances are more likely to experience both life stress and exposure to neurotoxic chemicals,” said senior author Amy Margolis.

Air pollution has negative effects on physical health, and recent work has begun to also show the effects on mental health. Life stress, particularly in early life, is one of the best-known contributors to mental health problems.

This new study examined the combined effects of air pollution and early life stress on school-age children.

According to the researchers data were collected from the CCCEH Mothers and Newborns longitudinal birth cohort study in Northern Manhattan and the Bronx, which includes many participants who self-identify as African American or Dominican.

Mothers wore an air monitoring backpack during the third trimester of pregnancy to measure exposure to air pollutants in their daily lives.

Stress
Stress is increasingly becoming a dreaded phenomenon. Lifetime Stock

When their children were 5 years old, mothers reported on stress in their lives, including neighbourhood quality, material hardship, intimate partner violence, perceived stress, lack of social support, and general distress levels.

Mothers then reported on their child’s psychiatric symptoms at ages 5, 7, 9 and 11.

The combined effect of air pollution and early life stress was seen across several measures of thought and attention problems/ADHD at the age 11.

The effects were also linked to PAH-DNA adducts–a dose-sensitive marker of air pollution exposure.

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The researchers said that PAH and early life stress may serve as a “double hit” on shared biological pathways connected to attention and thought problems.

Stress likely leads to wide-ranging changes in, for example, epigenetic expression, cortisol, inflammation, and brain structure and function.

The mechanism underlying the effects of PAH is still being interrogated; however, alterations in brain structure and function represent possible shared mechanistic pathways, the study said. (IANS)