Saturday August 18, 2018

Diabetes would become a curable disease in the next few years, say researchers

0
//
104
Republish
Reprint

diabetes-777002_640

Washington: Although the way diabetics test their glucose levels has gone through dramatic changes over the past 50 years, there is still a long way to go, say researchers.

Earlier, the only way to assess diabetes control was by testing for the presence of sugar in a person’s urine, today there are numerous, far more accurate ways to test blood glucose levels.

There is a non-invasive A1C method which measures average blood glucose levels over a three-month period.

“This gives us a nice marker for showing whether a person is on the right road or not,” said Fred Whitehouse, division head emeritus at the Henry Ford Health System in Detroit.

“There has been a lot of change, most of it for the better. But what people want is a cure and we don’t have that yet”, he added.

“Despite the enormous growth in our understanding of diabetes and its complications, we are still only able to manage the disease,” noted Robert Ratner, Chief Scientific and Medical Officer for the American Diabetes Association.

The reason diabetes is a serious health problem is because of the complications.

“If there were no complications, diabetes would be like hypothyroidism and other easily managed diseases. You would take a tablet to replace the hormone and everything would be fine,” said Michael Brownlee from the Albert Einstein College of Medicine’s Diabetes Research Centre.

New treatments must provide optimal glucose and metabolic control without the risk of hypoglycemia and complications of diabetes should become historical memories.

Also, every person with diabetes needs to create a system for remembering and dealing with his or her own treatment.

“The next 50 years must elucidate the mechanisms by which both Type 1 and Type 2 diabetes occur, along with those critical steps at which we might intervene to prevent disease,” the authors emphasized during a special symposium held recently at the American Diabetes Association’s 75th scientific sessions. (IANS)

Click here for reuse options!
Copyright 2015 NewsGram

Next Story

Here’s How Mushrooms can Help in the Treatment of Diabetes

Managing glucose better has implications for diabetes, as well as other metabolic diseases

0
Mushrooms
How mushrooms can aid in diabetes treatment, Find out here. Pixabay

Eating white button mushrooms daily can act as a prebiotic by improving microbial community in the gut, which could then improve the regulation of glucose in the liver, a finding that could one day pave way for new diabetes treatments, say researchers.

In the study, feeding white button mushrooms to mice changed the composition of gut microbes — microbiota — to produce more short chain fatty acids, specifically propionate from succinate, according to Margherita T. Cantorna, Professor at Pennsylvania State University in the US.

Previous research has shown that succinate and propionate can change the expression of genes needed to manage glucose production, she said.

“Managing glucose better has implications for diabetes, as well as other metabolic diseases,” Cantorna noted.

The study, reported in the Journal of Functional Foods, used two types of mice who were fed about a daily serving size of the mushrooms. One group had microbiota, the other were germ-free.

Mushrooms
Mushrooms. Pixabay

Consuming the mushrooms set off a chain reaction among the gut bacteria, expanding the population of Prevotella — a bacteria that produces propionate and succinate.

These acids can change the expression of genes that are key to the pathway between the brain and the gut that helps manage the production of glucose, or gluconeogenesis.

You May Also Like to Read About New Model Developed to Trace Heart Disease Risk- New AI Model to Identify the Risk of Heart Disease in Indians

The mushrooms, in this case, serve as a prebiotic, which is a substance that feeds beneficial bacteria that are already existing in the gut. Probiotics are live beneficial bacteria that are introduced into the digestive system.

Beyond the possible beneficial benefits of mushrooms as a prebiotic, Cantorna said that this study also shows more evidence that there is a tight connection between diet and microbiota.

“It’s pretty clear that almost any change you make to the diet, changes the microbiota,” Cantorna added. (IANS)