Tuesday December 10, 2019

Exposure to Dim Light Escalates Breast Cancer’s Spread to Bones

X-ray images showed that mice exposed to a light or dim light cycle had much larger tumours and increased bone damage compared with mice kept in a standard light/dark cycle

0
//
Cancer
Cancer Ribbon. Pixabay

Exposure to dim light at night may contribute to spreading of breast cancer to bones, researchers have shown in an animal study.

When breast cancer spreads it often affects bones, cause severe pain and make them fragile. “To date no one has reported that exposure to dim light at night induces circadian disruption, which increases spread of bone metastatic breast cancer,” said Muralidharan Anbalagan, Assistant Professor, at Tulane University in New Orleans.

The findings were presented at ENDO 2019, the Endocrine Society’s annual meeting in New Orleans.

For the preliminary study, the team created a mouse model of bone metastatic breast cancer. They injected oestrogen receptor-positive human breast cancer cells, which have a low propensity to grow in bones, into the tibia (shinbone) of female mice.

Cancer patient
Cancer patient.

Like humans, mice produced a strong night-time circadian melatonin signal, shown to produce strong anti-cancer actions and for promoting sleep.

While one group of mice was kept in the light for 12 hours each day, the other group of three mice in the dark for 12 hours. Another group spent 12 hours in light, followed by 12 hours in dim light at night.

Also Read- Connecting to Free Wi-Fi can Expose your Data to Hackers

X-ray images showed that mice exposed to a light or dim light cycle had much larger tumours and increased bone damage compared with mice kept in a standard light/dark cycle, he noted.

“Our research identified the importance of an intact nocturnal circadian melatonin anti-cancer signal in suppressing bone-metastatic breast tumour growth,” Anbalagan said. (IANS)

Next Story

Here are Ways to Protect your Bones as you Age

Here's how to protect your bones as you age

0
Bones
Here are ways to take care of your bones and improve your bone health as you age. Lifetime Stock

The skeleton system of our body plays a vital role throughout our lifetime. It acts as pillar of support for our body’s framework and protects our vital organs. Additionally, bones help in storing minerals like calcium and phosphorous, as well as support the muscles for locomotion. From birth to old age our bones go through series of changes.

By the age of 30, the bone mass density reaches its peak. After which it tends to lose more bone mass than it is deposited. Osteoporosis is a frequently occurring condition developed by people as they grow old. In this condition, bones become weak and fragile. Consequently, it becomes difficult to heal a broken bone after an osteoporotic fracture.

According to statistics, adult population above the age of 50 tends to break their bones easily. Where it is seen, 1 in 2 women and 1 in 4 men fracture their bones due to osteoporosis. Hence, it is important to take care of our bones from young to old age.

Skeleton bones
By the age of 30, the bone mass density reaches its peak. Lifetime Stock

There are certain risk factors which may act as a catalyst for accelerating osteoporosis early. Lack of vitamin D and calcium in diet, lack of physical activity, being underweight, smoking and drinking, irregular hormonal levels and intake of certain medications are some common examples of risk factors.

The risk factors increase the vulnerability of osteoporosis as we age. Dr Harish Ghoota, Additional Director-Orthopaedics, Fortis Escorts Hospital, Faridabad shares the following steps to incorporate in your lifestyle to better bone health:

  • Incorporating food and drinks rich in calcium and vitamin D is a good step. For example, low-fat dairy, tofu, soy milk, green leafy vegetables, leguminous pulses, salmon and nuts are good sources for calcium. Exposing one’s body to sunlight for 10-15 minutes twice or thrice a week acts as a good source for vitamin D. Food products like fortified milk and cereals, salmon, tuna, shrimp and oysters are also good sources for vitamin
  •  Indulging in regular exercise for minimum half an hour keeps the muscles and bones strong. Strength building, weight training exercises and dancing are one of the best ways to keep fit and healthy bones
  • Avoid tobacco and alcohol abuse. According to medical advice, women should not consume more than one drink per day and men should not consume more than two drinks per day
  • With increasing age, regular bone density tests and health check-ups with doctors helps prevent excessive bone density loss.
    Exercise bones
    Exercising everyday is beneficial for your bones. Lifetime Stock

    Taking care of your bones from a young age becomes essential to prevent poor bone health. During childhood and adolescent years, bones rapidly grow. These form crucial years for developing good bone health. Proper balanced diet with increased intake of calcium rich foods and minimum one hour of physical exercise everyday helps to maintain good bone health. Additionally, adults after 30 years of age must integrate healthy lifestyle practices. These activities help to prevent poor bone health after the age of 30:

  • Exercising daily for 30 minutes least
  • Being cautious from falls or accidents
  • Going for regular check-ups
  • Regular bone density tests. Especially, after age of 50 with a fractured bone

Also Read- 6 DIY Home Decor Ideas and Tips for Indian Homes

  • Additional intake of calcium and vitamin D over the age of 50
  • Regular medication, if prescribed by doctor, for bone density
  • Periodic Dexa scan test for high risk or vulnerable patients. (IANS)